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1

Human umbilical cord plasma proteins revitalize hippocampal function in aged mice.

Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T. Castellano JM, et al. Among authors: Xie XS. Nature. 2017 Apr 27;544(7651):488-492. doi: 10.1038/nature22067. Epub 2017 Apr 19. Nature. 2017. PMID: 28424512 Free PMC article.

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2

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T. Villeda SA, et al. Among authors: Xie XS. Nature. 2011 Aug 31;477(7362):90-4. doi: 10.1038/nature10357. Nature. 2011. PMID: 21886162 Free PMC article.

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3

CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming.

Liu Y, Yu C, Daley TP, Wang F, Cao WS, Bhate S, Lin X, Still C 2nd, Liu H, Zhao D, Wang H, Xie XS, Ding S, Wong WH, Wernig M, Qi LS. Liu Y, et al. Among authors: Xie XS. Cell Stem Cell. 2018 Nov 1;23(5):758-771.e8. doi: 10.1016/j.stem.2018.09.003. Epub 2018 Oct 11. Cell Stem Cell. 2018. PMID: 30318302 Free PMC article.

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4

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.

Villeda SA, Plambeck KE, Middeldorp J, Castellano JM, Mosher KI, Luo J, Smith LK, Bieri G, Lin K, Berdnik D, Wabl R, Udeochu J, Wheatley EG, Zou B, Simmons DA, Xie XS, Longo FM, Wyss-Coray T. Villeda SA, et al. Among authors: Xie XS. Nat Med. 2014 Jun;20(6):659-63. doi: 10.1038/nm.3569. Epub 2014 May 4. Nat Med. 2014. PMID: 24793238 Free PMC article.

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5

Optimization of Optomotor Response-based Visual Function Assessment in Mice.

Shi C, Yuan X, Chang K, Cho KS, Xie XS, Chen DF, Luo G. Shi C, et al. Among authors: Xie XS. Sci Rep. 2018 Jun 26;8(1):9708. doi: 10.1038/s41598-018-27329-w. Sci Rep. 2018. PMID: 29946119 Free PMC article.

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6

The neuronal circuit between nociceptin/orphanin FQ and hypocretins/orexins coordinately modulates stress-induced analgesia and anxiety-related behavior.

Xie XS. Xie XS. Vitam Horm. 2015;97:295-321. doi: 10.1016/bs.vh.2014.11.004. Epub 2015 Jan 20. Vitam Horm. 2015. PMID: 25677777 Review.

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7

Analgesic Microneedle Patch for Neuropathic Pain Therapy.

Xie X, Pascual C, Lieu C, Oh S, Wang J, Zou B, Xie J, Li Z, Xie J, Yeomans DC, Wu MX, Xie XS. Xie X, et al. Among authors: Xie J, Xie J, Xie XS. ACS Nano. 2017 Jan 24;11(1):395-406. doi: 10.1021/acsnano.6b06104. Epub 2016 Dec 27. ACS Nano. 2017. PMID: 28001346 Free PMC article.

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8

Chronic intermittent nicotine delivery via lung alveolar region-targeted aerosol technology produces circadian pharmacokinetics in rats resembling human smokers.

Shao XM, Liu S, Lee ES, Fung D, Pei H, Liang J, Mudgway R, Zhang J, Feldman JL, Zhu Y, Louie S, Xie XS. Shao XM, et al. Among authors: Xie XS. J Appl Physiol (1985). 2018 Nov 1;125(5):1555-1562. doi: 10.1152/japplphysiol.00357.2018. Epub 2018 Sep 20. J Appl Physiol (1985). 2018. PMID: 30236046 Free PMC article.

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9

Direct activation of G-protein-gated inward rectifying K+ channels promotes nonrapid eye movement sleep.

Zou B, Cao WS, Guan Z, Xiao K, Pascual C, Xie J, Zhang J, Xie J, Kayser F, Lindsley CW, Weaver CD, Fang J, Xie XS. Zou B, et al. Among authors: Xie J, Xie J, Xie XS. Sleep. 2019 Mar 1;42(3):zsy244. doi: 10.1093/sleep/zsy244. Sleep. 2019. PMID: 30535004 Free PMC article.

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10

The Anti-Amyloid-β and Neuroprotective Properties of a Novel Tricyclic Pyrone Molecule.

Maezawa I, Zou B, Di Lucente J, Cao WS, Pascual C, Weerasekara S, Zhang M, Xie XS, Hua DH, Jin LW. Maezawa I, et al. Among authors: Xie XS. J Alzheimers Dis. 2017;58(2):559-574. doi: 10.3233/JAD-161175. J Alzheimers Dis. 2017. PMID: 28482635 Free PMC article.

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