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The following term was not found in PubMed: gxuelong
Page 1
Showing results for gxuelong fu
Search for Xuelong Fu instead (1 results)
ERRATUM.
Furutani A, Sowa Y, Fujiwara H, Otsuji E, Sakai T. Furutani A, et al. Oncol Res. 2016 Jan 21;23(1):87. doi: 10.3727/096504016X14514194509664. Oncol Res. 2016. PMID: 29021025 Free PMC article.
Histone deacetylase (HDAC) inhibitors have been shown to enhance the effects of 5-fluorouracil (5-FU) against various cancer cells; however, no report has shown that an HDAC inhibitor may enhance the effects of 5-FU with radiation. Therefore, we investigated whether …
Histone deacetylase (HDAC) inhibitors have been shown to enhance the effects of 5-fluorouracil (5-FU) against various cancer cells; h …
5-FU Cardiotoxicity: Vasospasm, Myocarditis, and Sudden Death.
More LA, Lane S, Asnani A. More LA, et al. Curr Cardiol Rep. 2021 Feb 3;23(3):17. doi: 10.1007/s11886-021-01441-2. Curr Cardiol Rep. 2021. PMID: 33537861 Review.
PURPOSE OF REVIEW: 5-fluorouracil (5-FU) is one of the most common causes of cardiotoxicity associated with chemotherapy. ...Here we summarize the mechanistic and clinical data available to guide clinicians in caring for patients with suspected 5-FU cardiotoxicity. …
PURPOSE OF REVIEW: 5-fluorouracil (5-FU) is one of the most common causes of cardiotoxicity associated with chemotherapy. ...Here we …
Therapeutic drug monitoring of 5-fluorouracil.
Lee JJ, Beumer JH, Chu E. Lee JJ, et al. Cancer Chemother Pharmacol. 2016 Sep;78(3):447-64. doi: 10.1007/s00280-016-3054-2. Epub 2016 May 23. Cancer Chemother Pharmacol. 2016. PMID: 27217046 Free PMC article. Review.
However, it is now well established that BSA-based 5-FU dosing is correlated with a wide variation of 5-FU systemic exposure. Pharmacokinetic (PK) studies of 5-FU systemic exposure have shown a wide range of interpatient variation of 5-FU plasma drug l …
However, it is now well established that BSA-based 5-FU dosing is correlated with a wide variation of 5-FU systemic exposure. …
Low miR-224-5p in exosomes confers colorectal cancer 5-FU resistance by upregulating S100A4.
Yan YY, Deng ZF, Wu XT, Lu Y, Zhu ZY, Wen Q, Zhang W, Zhang HY, Chen XZ, Wu YS, He XB, Ma ZA, Li JS, Bi H, Zhang JY. Yan YY, et al. Drug Resist Updat. 2025 Mar;79:101211. doi: 10.1016/j.drup.2025.101211. Epub 2025 Feb 6. Drug Resist Updat. 2025. PMID: 39956015
This study aimed to identify molecular markers that mediate 5-fluorouracil (5-FU) resistance in colorectal cancer (CRC). Exosomes from 5-FU resistant CRC cells (HCT-15/FU) significantly enhanced the resistance to 5-FU and the malignant properties of HC …
This study aimed to identify molecular markers that mediate 5-fluorouracil (5-FU) resistance in colorectal cancer (CRC). Exosomes fro …
5-Fluorouracil-induced exacerbation of rosacea.
Haddock ES, Cohen PR. Haddock ES, et al. Dermatol Online J. 2016 Nov 15;22(11):13030/qt9n4377w6. Dermatol Online J. 2016. PMID: 28329576 Free article. Review.
Albeit rarely, exacerbation of rosacea by topical 5-FU treatment has been described when 5-FU was introduced as a topical treatment for actinic keratosis.Conclusion Topical 5-FU has been associated with several adverse cutaneous events, including accentuation …
Albeit rarely, exacerbation of rosacea by topical 5-FU treatment has been described when 5-FU was introduced as a topical trea …
Review of 5-FU resistance mechanisms in colorectal cancer: clinical significance of attenuated on-target effects.
Gmeiner WH, Okechukwu CC. Gmeiner WH, et al. Cancer Drug Resist. 2023 Apr 29;6(2):257-272. doi: 10.20517/cdr.2022.136. eCollection 2023. Cancer Drug Resist. 2023. PMID: 37457133 Free PMC article. Review.
The causes of 5-FU resistance are multi-factorial, and besides DNA mismatch repair deficiency (MMR-D), there are no widely accepted criteria for determining which CRC patients are not likely to be responsive to 5-FU-based therapy. Thus, there is a need to systematic …
The causes of 5-FU resistance are multi-factorial, and besides DNA mismatch repair deficiency (MMR-D), there are no widely accepted c …
Bio-based Carbon dots Loaded with 5-Fu: A Multifunctional drug Delivery System.
Feng B, Li N, Bi Y, Kong F, Wang Z, Tan S. Feng B, et al. J Fluoresc. 2024 Jul;34(4):1683-1692. doi: 10.1007/s10895-023-03385-y. Epub 2023 Aug 18. J Fluoresc. 2024. PMID: 37594586
The results also showed that AMP-CDs@5-Fu could be used to reduce the toxicity of 5-Fu while significantly improving the anticancer ability. In vitro hemolysis and anticancer assays showed that AMP-CDs@5-Fu could significantly improve the anticancer ability w …
The results also showed that AMP-CDs@5-Fu could be used to reduce the toxicity of 5-Fu while significantly improving the antic …
5-Fluorouracil-related Cardiotoxicity with Coronary Vasospasms.
Faheem B, Kania B, Ashkar H, Bondili L, Maroules M. Faheem B, et al. J Community Hosp Intern Med Perspect. 2022 Sep 9;12(5):71-74. doi: 10.55729/2000-9666.1094. eCollection 2022. J Community Hosp Intern Med Perspect. 2022. PMID: 36262502 Free PMC article.
Management of cardiotoxic adverse effects includes discontinuing 5-FU therapy if the patient can tolerate an alternative regimen or initiating prophylactic antianginal treatments with very close monitoring of the patient while they receive 5-FU therapy. Here, we des …
Management of cardiotoxic adverse effects includes discontinuing 5-FU therapy if the patient can tolerate an alternative regimen or i …
How can we best monitor 5-FU administration to maximize benefit to risk ratio?
Goirand F, Lemaitre F, Launay M, Tron C, Chatelut E, Boyer JC, Bardou M, Schmitt A. Goirand F, et al. Expert Opin Drug Metab Toxicol. 2018 Dec;14(12):1303-1313. doi: 10.1080/17425255.2018.1550484. Epub 2018 Nov 23. Expert Opin Drug Metab Toxicol. 2018. PMID: 30451549 Free article. Review.
5-Fluorouracil (5-FU) is currently used as a chemotherapy in several cancers such as head-and-neck (H&N) and colorectal cancers. 5-FU dosing is traditionally based on body surface area (BSA), but this strategy is usually associated with severe toxicities. 5-F …
5-Fluorouracil (5-FU) is currently used as a chemotherapy in several cancers such as head-and-neck (H&N) and colorectal cancers. …
SPOCK1 silencing decreases 5-FU resistance through PRRX1 in colorectal cancer.
Qu YL, Liu XL, Zhao SY, Zhai XF. Qu YL, et al. Pathol Res Pract. 2022 Jun;234:153895. doi: 10.1016/j.prp.2022.153895. Epub 2022 Apr 12. Pathol Res Pract. 2022. PMID: 35462225
However, the relationship between development of resistance to 5-FU and SPOCK1 remain unclear. In this study, we established two 5-fluorouracil (5-FU)-resistant CRC cell lines, HCT116/FU and LOVO/FU, and found that SPOCK1 is upregulated in 5-FU- …
However, the relationship between development of resistance to 5-FU and SPOCK1 remain unclear. In this study, we established two 5-fl …
234,604 results
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