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Year Number of Results
1985 1
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2005 1
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2013 2
2014 1
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2016 2
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35 results

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Page 1
Lung adenocarcinoma promotion by air pollutants.
Hill W, Lim EL, Weeden CE, Lee C, Augustine M, Chen K, Kuan FC, Marongiu F, Evans EJ Jr, Moore DA, Rodrigues FS, Pich O, Bakker B, Cha H, Myers R, van Maldegem F, Boumelha J, Veeriah S, Rowan A, Naceur-Lombardelli C, Karasaki T, Sivakumar M, De S, Caswell DR, Nagano A, Black JRM, Martínez-Ruiz C, Ryu MH, Huff RD, Li S, Favé MJ, Magness A, Suárez-Bonnet A, Priestnall SL, Lüchtenborg M, Lavelle K, Pethick J, Hardy S, McRonald FE, Lin MH, Troccoli CI, Ghosh M, Miller YE, Merrick DT, Keith RL, Al Bakir M, Bailey C, Hill MS, Saal LH, Chen Y, George AM, Abbosh C, Kanu N, Lee SH, McGranahan N, Berg CD, Sasieni P, Houlston R, Turnbull C, Lam S, Awadalla P, Grönroos E, Downward J, Jacks T, Carlsten C, Malanchi I, Hackshaw A, Litchfield K; TRACERx Consortium; DeGregori J, Jamal-Hanjani M, Swanton C. Hill W, et al. Nature. 2023 Apr;616(7955):159-167. doi: 10.1038/s41586-023-05874-3. Epub 2023 Apr 5. Nature. 2023. PMID: 37020004 Free PMC article.
Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors.
Musiani D, Yücel H, Vallette M, Angrisani A, El Botty R, Ouine B, Schintu N, Adams C, Chevalier M, Heloise D, El Marjou A, Nemazanyy I, Regairaz M, Marangoni E, Fachinetti D, Ceccaldi R. Musiani D, et al. Mol Cell. 2025 Mar 20;85(6):1072-1084.e10. doi: 10.1016/j.molcel.2025.01.031. Epub 2025 Feb 25. Mol Cell. 2025. PMID: 40010343 Free article.
We found that the interplay between the two major uracil DNA glycosylases UNG and SMUG1 is regulated by nuclear nicotinamide adenine dinucleotide (NAD(+)), which maintains UNG at replication forks (RFs) and restrains SMUG1 chromatin binding. ...Our findings open up …
We found that the interplay between the two major uracil DNA glycosylases UNG and SMUG1 is regulated by nuclear nicotinamide adenine …
Conflict of Interest Disclosures.
[No authors listed] [No authors listed] Global Spine J. 2025 May;15(2_suppl):793S-822S. doi: 10.1177/21925682251336882. Epub 2025 May 21. Global Spine J. 2025. PMID: 40397527 Free PMC article. No abstract available.
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Pan X, AbdulJabbar K, Coelho-Lima J, Grapa AI, Zhang H, Cheung AHK, Baena J, Karasaki T, Wilson CR, Sereno M, Veeriah S, Aitken SJ, Hackshaw A, Nicholson AG, Jamal-Hanjani M; TRACERx Consortium; Swanton C, Yuan Y, Le Quesne J, Moore DA. Pan X, et al. Nat Cancer. 2024 Feb;5(2):347-363. doi: 10.1038/s43018-023-00694-w. Epub 2024 Jan 10. Nat Cancer. 2024. PMID: 38200244 Free PMC article.
Chemoproteogenomic stratification of the missense variant cysteinome.
Desai H, Andrews KH, Bergersen KV, Ofori S, Yu F, Shikwana F, Arbing MA, Boatner LM, Villanueva M, Ung N, Reed EF, Nesvizhskii AI, Backus KM. Desai H, et al. Nat Commun. 2024 Oct 28;15(1):9284. doi: 10.1038/s41467-024-53520-x. Nat Commun. 2024. PMID: 39468056 Free PMC article.
Programmable DNA pyrimidine base editing via engineered uracil-DNA glycosylase.
Yi Z, Zhang X, Wei X, Li J, Ren J, Zhang X, Zhang Y, Tang H, Chang X, Yu Y, Wei W. Yi Z, et al. Nat Commun. 2024 Jul 30;15(1):6397. doi: 10.1038/s41467-024-50012-w. Nat Commun. 2024. PMID: 39080265 Free PMC article.
In this study, we successfully achieve base editing of both cytidine and thymine by leveraging the translesion DNA synthesis pathway through the engineering of uracil-DNA glycosylase (UNG). Employing structure-based rational design, exploration of homologous proteins, and …
In this study, we successfully achieve base editing of both cytidine and thymine by leveraging the translesion DNA synthesis pathway through …
Machine learning derived retinal pigment score from ophthalmic imaging shows ethnicity is not biology.
Rajesh AE, Olvera-Barrios A, Warwick AN, Wu Y, Stuart KV, Biradar MI, Ung CY, Khawaja AP, Luben R, Foster PJ, Cleland CR, Makupa WU, Denniston AK, Burton MJ, Bastawrous A, Keane PA, Chia MA, Turner AW, Lee CS, Tufail A, Lee AY, Egan C; UK Biobank Eye and Vision Consortium. Rajesh AE, et al. Nat Commun. 2025 Jan 2;16(1):60. doi: 10.1038/s41467-024-55198-7. Nat Commun. 2025. PMID: 39746957 Free PMC article.
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma.
Biswas D, Liu YH, Herrero J, Wu Y, Moore DA, Karasaki T, Grigoriadis K, Lu WT, Veeriah S, Naceur-Lombardelli C, Magno N, Ward S, Frankell AM, Hill MS, Colliver E, de Carné Trécesson S, East P, Malhi A, Snell DM, O'Neill O, Leonce D, Mattsson J, Lindberg A, Micke P, Moldvay J, Megyesfalvi Z, Dome B, Fillinger J, Nicod J, Downward J, Szallasi Z; TRACERx Consortium; Hackshaw A, Jamal-Hanjani M, Kanu N, Birkbak NJ, Swanton C. Biswas D, et al. Nat Cancer. 2025 Jan;6(1):86-101. doi: 10.1038/s43018-024-00883-1. Epub 2025 Jan 9. Nat Cancer. 2025. PMID: 39789179 Free PMC article.
35 results