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The following term was not found in PubMed: Ya-Chuan
Page 1
Did you mean yan chun bo (5 results)?
Animal models of atherosclerosis.
Kapourchali FR, Surendiran G, Chen L, Uitz E, Bahadori B, Moghadasian MH. Kapourchali FR, et al. World J Clin Cases. 2014 May 16;2(5):126-32. doi: 10.12998/wjcc.v2.i5.126. World J Clin Cases. 2014. PMID: 24868511 Free PMC article. Review.
This mouse model of hypercholesterolemia and atherosclerosis has been also used to investigate the impact of oxidative stress and inflammation on atherogenesis. Low density lipoprotein (LDL)-r-KO mice are a model of human familial hypercholesterolemia. However, unlike apo …
This mouse model of hypercholesterolemia and atherosclerosis has been also used to investigate the impact of oxidative stress and inflammati …
A reexamination of krill oil bioavailability studies.
Salem N Jr, Kuratko CN. Salem N Jr, et al. Lipids Health Dis. 2014 Aug 26;13:137. doi: 10.1186/1476-511X-13-137. Lipids Health Dis. 2014. PMID: 25156381 Free PMC article.
It has proven difficult to compare the bioavailability of krill oil (KO) vs. fish oil (FO) due to several of the characteristics of KO. These include the lower concentration of the active ingredients, eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DH …
It has proven difficult to compare the bioavailability of krill oil (KO) vs. fish oil (FO) due to several of the characteristics of …
Mice Lacking Gpr75 are Hypophagic and Thin.
Powell DR, Doree DD, DaCosta CM, Platt KA, Brommage R, Buhring L, Revelli JP, Shadoan MK. Powell DR, et al. Diabetes Metab Syndr Obes. 2022 Jan 5;15:45-58. doi: 10.2147/DMSO.S342799. eCollection 2022. Diabetes Metab Syndr Obes. 2022. PMID: 35023939 Free PMC article.
METHODS: Gpr75 KO mice were generated by homologous recombination. All studies compared female and male Gpr75 KO mice to their wild type (WT) littermates. ...RESULTS: In all 12 cohorts of adult female or male mice, Gpr75 KO mice had less body fat; pooled data …
METHODS: Gpr75 KO mice were generated by homologous recombination. All studies compared female and male Gpr75 KO mice to their …
Disruption of Mitochondrial Dynamics and Stasis Leads to Liver Injury and Tumorigenesis.
Ma X, Wei X, Niu M, Zhang C, Peng Z, Liu W, Yan J, Su X, Lu S, Cui W, Sesaki H, Zong WX, Ni HM, Ding WX. Ma X, et al. bioRxiv [Preprint]. 2025 Feb 12:2025.02.11.637688. doi: 10.1101/2025.02.11.637688. bioRxiv. 2025. PMID: 39990472 Free PMC article. Preprint.
METHODS: Dnm1l Flox/Flox ( Dnm1l (F/F) ), Mfn1 (F/F) and Mfn2 (F/F) mice were crossed with albumin-Cre mice to generate liver-specific Dnm1l knockout (L- Dnm1l KO), L- Mfn1 KO, L- Mfn2 KO, L- Mfn1, Mfn2 double KO (DKO), and L- Mfn1, Mfn2, Dnm1l triple …
METHODS: Dnm1l Flox/Flox ( Dnm1l (F/F) ), Mfn1 (F/F) and Mfn2 (F/F) mice were crossed with albumin-Cre mice to generate liver-specific Dnm1l …
Untargeted metabolomics uncovers metabolic dysregulation and tissue sensitivity in ACE2 knockout mice.
Zhao L, Yang W, Ji W, Pan Q, Yang J, Cao X. Zhao L, et al. Heliyon. 2024 Mar 8;10(6):e27472. doi: 10.1016/j.heliyon.2024.e27472. eCollection 2024 Mar 30. Heliyon. 2024. PMID: 38496880 Free PMC article.
The results showed significant alterations in metabolic profiling in ACE2 KO mice. We identified 275 and 168 serum metabolites differing significantly between WT and ACE2 KO mice fed on ND and HFD, respectively. ...Interestingly, DL-tryptophan, indole and Gly-Phe de …
The results showed significant alterations in metabolic profiling in ACE2 KO mice. We identified 275 and 168 serum metabolites differ …
Comprehensive knockout analysis of the RAB family small GTPases reveals an overlapping role of RAB2 and RAB14 in autophagosome maturation.
Haga K, Fukuda M. Haga K, et al. Autophagy. 2025 Jan;21(1):21-36. doi: 10.1080/15548627.2024.2374699. Epub 2024 Jul 10. Autophagy. 2025. PMID: 38953305
The results revealed clear alteration of the MAP1LC3/LC3-II level in only four rab-KO cells (rab1-KO, rab2-KO, rab7a-KO, and rab14-KO cells) and identified RAB14 as a new regulator of autophagy, specifically at the autophagosome maturation step. …
The results revealed clear alteration of the MAP1LC3/LC3-II level in only four rab-KO cells (rab1-KO, rab2-KO, rab7a- …
Endothelial-derived FABP4 constitutes the majority of basal circulating hormone and regulates lipolysis-driven insulin secretion.
Inouye KE, Prentice KJ, Lee A, Wang ZB, Dominguez-Gonzalez C, Chen MX, Riveros JK, Burak MF, Lee GY, Hotamışlıgil GS. Inouye KE, et al. JCI Insight. 2023 Jul 24;8(14):e164642. doi: 10.1172/jci.insight.164642. JCI Insight. 2023. PMID: 37279064 Free PMC article.
We generated mice with Fabp4 deletion in cells known to express the gene - adipocytes (Adipo-KO), endothelial cells (Endo-KO), myeloid cells (Myeloid-KO), and the whole body (Total-KO) - to examine the contribution of these cell types to basal and stim …
We generated mice with Fabp4 deletion in cells known to express the gene - adipocytes (Adipo-KO), endothelial cells (Endo-KO), …
Germline ablation achieved via CRISPR/Cas9 targeting of NANOS3 in bovine zygotes.
Mueller ML, McNabb BR, Owen JR, Hennig SL, Ledesma AV, Angove ML, Conley AJ, Ross PJ, Van Eenennaam AL. Mueller ML, et al. Front Genome Ed. 2023 Nov 27;5:1321243. doi: 10.3389/fgeed.2023.1321243. eCollection 2023. Front Genome Ed. 2023. PMID: 38089499 Free PMC article.
In NANOS3 KO fetal testes, PGCs were found to be completely eliminated by 41-day of fetal age. ...Additionally, a live, NANOS3 KO, germline-ablated heifer was produced. However, it was evident that the absence of germ cells in NANOS3 KO cattle compromised the …
In NANOS3 KO fetal testes, PGCs were found to be completely eliminated by 41-day of fetal age. ...Additionally, a live, NANOS3 KO …
The gut microbiotas with metabolites regulate the protective role of miR-30a-5p in myocardial infarction.
Wang R, Chen RL, Wu C, Zhang XC, Wu WY, Dai C, Wang Y, Li G. Wang R, et al. J Adv Res. 2024 Oct 21:S2090-1232(24)00472-7. doi: 10.1016/j.jare.2024.10.017. Online ahead of print. J Adv Res. 2024. PMID: 39442873 Free article.
KO exacerbated intestinal barrier structure deterioration and further downregulated the expression of Cloudin-1, Occludin, and ZO-1 in MI mice. 16S rDNA sequencing-analyzed gut microbiome of KO and WT mice found that KO mainly reduced g_Lactobacillus. ...Anal …
KO exacerbated intestinal barrier structure deterioration and further downregulated the expression of Cloudin-1, Occludin, and ZO-1 i …
Organ Correlation with Tryptophan Metabolism Obtained by Analyses of TDO-KO and QPRT-KO Mice.
Shibata K, Fukuwatari T. Shibata K, et al. Int J Tryptophan Res. 2016 Apr 28;9:1-7. doi: 10.4137/IJTR.S37984. eCollection 2016. Int J Tryptophan Res. 2016. PMID: 27147825 Free PMC article. Review.
The aim of this article is to report the organ-specific correlation with tryptophan (Trp) metabolism obtained by analyses of tryptophan 2,3-dioxygenase knockout (TDO-KO) and quinolinic acid phosphoribosyltransferase knockout (QPRT-KO) mice models. We found that TDO- …
The aim of this article is to report the organ-specific correlation with tryptophan (Trp) metabolism obtained by analyses of tryptophan 2,3- …
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