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Peripheral administration of the N-terminal pro-opiomelanocortin fragment 1-28 to Pomc-/- mice reduces food intake and weight but does not affect adrenal growth or corticosterone production.
Coll AP, Fassnacht M, Klammer S, Hahner S, Schulte DM, Piper S, Tung YC, Challis BG, Weinstein Y, Allolio B, O'Rahilly S, Beuschlein F. Coll AP, et al. Among authors: weinstein y. J Endocrinol. 2006 Aug;190(2):515-25. doi: 10.1677/joe.1.06749. J Endocrinol. 2006. PMID: 16899584 Free PMC article.