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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 10
2003 20
2004 24
2005 24
2006 26
2007 38
2008 31
2009 30
2010 40
2011 41
2012 43
2013 48
2014 82
2015 81
2016 71
2017 63
2018 76
2019 98
2020 74
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813 results
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Page 1
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C; Alzheimer’s Disease Neuroimaging Initiative, Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. Shi Y, et al. Nature. 2017 Sep 28;549(7673):523-527. doi: 10.1038/nature24016. Epub 2017 Sep 20. Nature. 2017. PMID: 28959956 Free PMC article.
LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.
Sheng W, LaFleur MW, Nguyen TH, Chen S, Chakravarthy A, Conway JR, Li Y, Chen H, Yang H, Hsu PH, Van Allen EM, Freeman GJ, De Carvalho DD, He HH, Sharpe AH, Shi Y. Sheng W, et al. Among authors: shi y. Cell. 2018 Jul 26;174(3):549-563.e19. doi: 10.1016/j.cell.2018.05.052. Epub 2018 Jun 21. Cell. 2018. PMID: 29937226 Free PMC article.
RNA m6A methylation regulates the ultraviolet-induced DNA damage response.
Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, Hsu PH, Zou L, Jambhekar A, He C, Shi Y. Xiang Y, et al. Among authors: shi y. Nature. 2017 Mar 23;543(7646):573-576. doi: 10.1038/nature21671. Epub 2017 Mar 15. Nature. 2017. PMID: 28297716 Free PMC article.
N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation.
Ma H, Wang X, Cai J, Dai Q, Natchiar SK, Lv R, Chen K, Lu Z, Chen H, Shi YG, Lan F, Fan J, Klaholz BP, Pan T, Shi Y, He C. Ma H, et al. Among authors: shi y. Nat Chem Biol. 2019 Jan;15(1):88-94. doi: 10.1038/s41589-018-0184-3. Epub 2018 Dec 10. Nat Chem Biol. 2019. PMID: 30531910 Free PMC article.
Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.
Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, Bernstein BE, Alani R, Golub TR, Cole PA, Filbin MG, Shi Y. Anastas JN, et al. Among authors: shi y. Cancer Cell. 2019 Nov 11;36(5):528-544.e10. doi: 10.1016/j.ccell.2019.09.005. Epub 2019 Oct 17. Cancer Cell. 2019. PMID: 31631026
Smart cancer nanomedicine.
van der Meel R, Sulheim E, Shi Y, Kiessling F, Mulder WJM, Lammers T. van der Meel R, et al. Among authors: shi y. Nat Nanotechnol. 2019 Nov;14(11):1007-1017. doi: 10.1038/s41565-019-0567-y. Epub 2019 Nov 6. Nat Nanotechnol. 2019. PMID: 31695150 Free PMC article.
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.
Wu D, Hu D, Chen H, Shi G, Fetahu IS, Wu F, Rabidou K, Fang R, Tan L, Xu S, Liu H, Argueta C, Zhang L, Mao F, Yan G, Chen J, Dong Z, Lv R, Xu Y, Wang M, Ye Y, Zhang S, Duquette D, Geng S, Yin C, Lian CG, Murphy GF, Adler GK, Garg R, Lynch L, Yang P, Li Y, Lan F, Fan J, Shi Y, Shi YG. Wu D, et al. Among authors: shi y. Nature. 2018 Jul;559(7715):637-641. doi: 10.1038/s41586-018-0350-5. Epub 2018 Jul 18. Nature. 2018. PMID: 30022161 Free PMC article.
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model.
Shi Y, Manis M, Long J, Wang K, Sullivan PM, Remolina Serrano J, Hoyle R, Holtzman DM. Shi Y, et al. J Exp Med. 2019 Nov 4;216(11):2546-2561. doi: 10.1084/jem.20190980. Epub 2019 Oct 10. J Exp Med. 2019. PMID: 31601677 Free PMC article.
PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.
Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. Zhang J, et al. Among authors: shi y. Cancer Discov. 2019 Sep;9(9):1306-1323. doi: 10.1158/2159-8290.CD-18-0083. Epub 2019 Jun 19. Cancer Discov. 2019. PMID: 31217297 Free PMC article.
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