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Modulators of 14-3-3 Protein-Protein Interactions.
Stevers LM, Sijbesma E, Botta M, MacKintosh C, Obsil T, Landrieu I, Cau Y, Wilson AJ, Karawajczyk A, Eickhoff J, Davis J, Hann M, O'Mahony G, Doveston RG, Brunsveld L, Ottmann C. Stevers LM, et al. Among authors: cau y. J Med Chem. 2018 May 10;61(9):3755-3778. doi: 10.1021/acs.jmedchem.7b00574. Epub 2017 Oct 19. J Med Chem. 2018. PMID: 28968506 Free PMC article. Review.
Structure, Function, Involvement in Diseases and Targeting of 14-3-3 Proteins: An Update.
Cau Y, Valensin D, Mori M, Draghi S, Botta M. Cau Y, et al. Curr Med Chem. 2018;25(1):5-21. doi: 10.2174/0929867324666170426095015. Curr Med Chem. 2018. PMID: 28462702 Review.
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction.
D'Agostino I, Giacchello I, Nannetti G, Fallacara AL, Deodato D, Musumeci F, Grossi G, Palù G, Cau Y, Trist IM, Loregian A, Schenone S, Botta M. D'Agostino I, et al. Among authors: cau y. Eur J Med Chem. 2018 Sep 5;157:743-758. doi: 10.1016/j.ejmech.2018.08.032. Epub 2018 Aug 13. Eur J Med Chem. 2018. PMID: 30142611
Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02.
Iralde-Lorente L, Cau Y, Clementi L, Franci L, Tassone G, Valensin D, Mori M, Angelucci A, Chiariello M, Botta M. Iralde-Lorente L, et al. Among authors: cau y. J Enzyme Inhib Med Chem. 2019 Dec;34(1):657-664. doi: 10.1080/14756366.2019.1574779. J Enzyme Inhib Med Chem. 2019. PMID: 30727786
Mycobacterial carbonic anhydrase inhibition with phenolic acids and esters: kinetic and computational investigations.
Cau Y, Mori M, Supuran CT, Botta M. Cau Y, et al. Org Biomol Chem. 2016 Sep 21;14(35):8322-30. doi: 10.1039/c6ob01477a. Epub 2016 Aug 17. Org Biomol Chem. 2016. PMID: 27530867
Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII.
Cau Y, Vullo D, Mori M, Dreassi E, Supuran CT, Botta M. Cau Y, et al. Molecules. 2017 Dec 22;23(1):17. doi: 10.3390/molecules23010017. Molecules. 2017. PMID: 29271882 Free PMC article.
Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing.
Mori M, Cau Y, Vignaroli G, Laurenzana I, Caivano A, Vullo D, Supuran CT, Botta M. Mori M, et al. Among authors: cau y. ACS Chem Biol. 2015 Sep 18;10(9):1964-9. doi: 10.1021/acschembio.5b00337. Epub 2015 Jul 1. ACS Chem Biol. 2015. PMID: 26121309
Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction.
Iralde-Lorente L, Tassone G, Clementi L, Franci L, Munier CC, Cau Y, Mori M, Chiariello M, Angelucci A, Perry MWD, Pozzi C, Mangani S, Botta M. Iralde-Lorente L, et al. Among authors: cau y. ACS Chem Biol. 2020 Apr 17;15(4):1026-1035. doi: 10.1021/acschembio.0c00039. Epub 2020 Mar 20. ACS Chem Biol. 2020. PMID: 32142251
Molecular insights to the bioactive form of BV02, a reference inhibitor of 14-3-3σ protein-protein interactions.
Valensin D, Cau Y, Calandro P, Vignaroli G, Dello Iacono L, Chiariello M, Mori M, Botta M. Valensin D, et al. Among authors: cau y. Bioorg Med Chem Lett. 2016 Feb 1;26(3):894-898. doi: 10.1016/j.bmcl.2015.12.066. Epub 2015 Dec 21. Bioorg Med Chem Lett. 2016. PMID: 26774582
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions.
Cau Y, Fiorillo A, Mori M, Ilari A, Botta M, Lalle M. Cau Y, et al. J Chem Inf Model. 2015 Dec 28;55(12):2611-22. doi: 10.1021/acs.jcim.5b00452. Epub 2015 Nov 19. J Chem Inf Model. 2015. PMID: 26551337
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