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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2002 3
2003 10
2004 3
2005 4
2006 17
2007 24
2008 32
2009 38
2010 39
2011 56
2012 52
2013 73
2014 51
2015 72
2016 52
2017 50
2018 53
2019 92
2020 85
2021 96
2022 115
2023 110
2024 109
2025 84

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1,173 results

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Page 1
Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Ma T, Tian X, Zhang B, Li M, Wang Y, Yang C, Wu J, Wei X, Qu Q, Yu Y, Long S, Feng JW, Li C, Zhang C, Xie C, Wu Y, Xu Z, Chen J, Yu Y, Huang X, He Y, Yao L, Zhang L, Zhu M, Wang W, Wang ZC, Zhang M, Bao Y, Jia W, Lin SY, Ye Z, Piao HL, Deng X, Zhang CS, Lin SC. Ma T, et al. Among authors: yu y. Nature. 2022 Mar;603(7899):159-165. doi: 10.1038/s41586-022-04431-8. Epub 2022 Feb 23. Nature. 2022. PMID: 35197629 Free PMC article.
Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing.
Qu Q, Chen Y, Wang Y, Wang W, Long S, Yang HY, Wu J, Li M, Tian X, Wei X, Liu YH, Xu S, Xiong J, Yang C, Wu Z, Huang X, Xie C, Wu Y, Xu Z, Zhang C, Zhang B, Feng JW, Chen J, Feng Y, Fang H, Lin L, Xie ZK, Sun B, Tian H, Yu Y, Piao HL, Xie XS, Deng X, Zhang CS, Lin SC. Qu Q, et al. Among authors: yu y. Nature. 2025 Jul;643(8070):201-209. doi: 10.1038/s41586-024-08348-2. Epub 2024 Dec 18. Nature. 2025. PMID: 39695235 Free PMC article.
AMPK-PDZD8-GLS1 axis mediates calorie restriction-induced lifespan extension.
Li M, Wang Y, Wei X, Cai WF, Liu YH, Wu J, Chen Y, Xiong J, Cui LF, Zhu M, Zhang C, Lin L, Yu Y, Piao HL, Lin SC, Zhang CS. Li M, et al. Among authors: yu y. Cell Res. 2024 Nov;34(11):806-809. doi: 10.1038/s41422-024-01021-3. Epub 2024 Sep 19. Cell Res. 2024. PMID: 39300254 Free PMC article. No abstract available.
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling.
Mendiola AS, Yan Z, Dixit K, Johnson JR, Bouhaddou M, Meyer-Franke A, Shin MG, Yong Y, Agrawal A, MacDonald E, Muthukumar G, Pearce C, Arun N, Cabriga B, Meza-Acevedo R, Alzamora MDPS, Zamvil SS, Pico AR, Ryu JK, Krogan NJ, Akassoglou K. Mendiola AS, et al. Among authors: yong y. Nat Immunol. 2023 Jul;24(7):1173-1187. doi: 10.1038/s41590-023-01522-0. Epub 2023 Jun 8. Nat Immunol. 2023. PMID: 37291385 Free PMC article.
Establishment of porcine and human expanded potential stem cells.
Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Chen ACH, Eckersley-Maslin MA, Ahmad S, Lee YL, Kobayashi T, Ryan D, Zhong J, Zhu J, Wu J, Lan G, Petkov S, Yang J, Antunes L, Campos LS, Fu B, Wang S, Yong Y, Wang X, Xue SG, Ge L, Liu Z, Huang Y, Nie T, Li P, Wu D, Pei D, Zhang Y, Lu L, Yang F, Kimber SJ, Reik W, Zou X, Shang Z, Lai L, Surani A, Tam PPL, Ahmed A, Yeung WSB, Teichmann SA, Niemann H, Liu P. Gao X, et al. Among authors: yong y. Nat Cell Biol. 2019 Jun;21(6):687-699. doi: 10.1038/s41556-019-0333-2. Epub 2019 Jun 3. Nat Cell Biol. 2019. PMID: 31160711 Free PMC article.
Hydrogel-Based Flexible Electronics.
Hu L, Chee PL, Sugiarto S, Yu Y, Shi C, Yan R, Yao Z, Shi X, Zhi J, Kai D, Yu HD, Huang W. Hu L, et al. Among authors: yu y. Adv Mater. 2023 Apr;35(14):e2205326. doi: 10.1002/adma.202205326. Epub 2023 Feb 22. Adv Mater. 2023. PMID: 36037508 Review.
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Zhang CS, Li M, Wang Y, Li X, Zong Y, Long S, Zhang M, Feng JW, Wei X, Liu YH, Zhang B, Wu J, Zhang C, Lian W, Ma T, Tian X, Qu Q, Yu Y, Xiong J, Liu DT, Wu Z, Zhu M, Xie C, Wu Y, Xu Z, Yang C, Chen J, Huang G, He Q, Huang X, Zhang L, Sun X, Liu Q, Ghafoor A, Gui F, Zheng K, Wang W, Wang ZC, Yu Y, Zhao Q, Lin SY, Wang ZX, Piao HL, Deng X, Lin SC. Zhang CS, et al. Among authors: yu y. Nat Metab. 2022 Oct;4(10):1369-1401. doi: 10.1038/s42255-022-00640-7. Epub 2022 Oct 10. Nat Metab. 2022. PMID: 36217034 Free PMC article.
Axonal spheroids in neurodegeneration.
Yong Y, Hunter-Chang S, Stepanova E, Deppmann C. Yong Y, et al. Mol Cell Neurosci. 2021 Dec;117:103679. doi: 10.1016/j.mcn.2021.103679. Epub 2021 Oct 19. Mol Cell Neurosci. 2021. PMID: 34678457 Free PMC article. Review.
1,173 results