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The Effect of Metformin in Treatment of Adenomas in Patients with Familial Adenomatous Polyposis.

Park JJ, Kim BC, Hong SP, Seo Y, Lee HS, Park YS, Na SY, Park SC, Park J, Kim JH, Moon CM, Huh KC, Park SJ, Cheon JH, Kim WH, Kim TI. Park JJ, et al. Among authors: seo y. Cancer Prev Res (Phila). 2021 May;14(5):563-572. doi: 10.1158/1940-6207.CAPR-20-0580. Epub 2021 Jan 28. Cancer Prev Res (Phila). 2021. PMID: 33509804 Clinical Trial.

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Metformin and Niclosamide Synergistically Suppress Wnt and YAP in APC-Mutated Colorectal Cancer.

Kang HE, Seo Y, Yun JS, Song SH, Han D, Cho ES, Cho SB, Jeon Y, Lee H, Kim HS, Kang J, Yook JI, Kim NH, Kim TI. Kang HE, et al. Among authors: seo y. Cancers (Basel). 2021 Jul 9;13(14):3437. doi: 10.3390/cancers13143437. Cancers (Basel). 2021. PMID: 34298652 Free PMC article.

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IL-6 and IL-8, secreted by myofibroblasts in the tumor microenvironment, activate HES1 to expand the cancer stem cell population in early colorectal tumor.

Kim B, Seo Y, Kwon JH, Shin Y, Kim S, Park SJ, Park JJ, Cheon JH, Kim WH, Il Kim T. Kim B, et al. Among authors: seo y. Mol Carcinog. 2021 Mar;60(3):188-200. doi: 10.1002/mc.23283. Epub 2021 Feb 5. Mol Carcinog. 2021. PMID: 33544929

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TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.

Soo Lee N, Jin Chung H, Kim HJ, Yun Lee S, Ji JH, Seo Y, Hun Han S, Choi M, Yun M, Lee SG, Myung K, Kim Y, Chul Kang H, Kim H. Soo Lee N, et al. Among authors: seo y. Nat Commun. 2016 Jan 19;7:10463. doi: 10.1038/ncomms10463. Nat Commun. 2016. PMID: 26781088 Free PMC article.

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Metformin Suppresses Cancer Stem Cells through AMPK Activation and Inhibition of Protein Prenylation of the Mevalonate Pathway in Colorectal Cancer.

Seo Y, Kim J, Park SJ, Park JJ, Cheon JH, Kim WH, Kim TI. Seo Y, et al. Cancers (Basel). 2020 Sep 8;12(9):2554. doi: 10.3390/cancers12092554. Cancers (Basel). 2020. PMID: 32911743 Free PMC article.

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Ring finger protein 126 (RNF126) suppresses ionizing radiation-induced p53-binding protein 1 (53BP1) focus formation.

Lee NS, Chang HR, Kim S, Ji JH, Lee J, Lee HJ, Seo Y, Kang M, Han JS, Myung K, Kim Y, Kim H. Lee NS, et al. Among authors: seo y. J Biol Chem. 2018 Jan 12;293(2):588-598. doi: 10.1074/jbc.M116.765602. Epub 2017 Nov 22. J Biol Chem. 2018. PMID: 29167269 Free PMC article.

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Publisher Correction: Effects of metformin on colorectal cancer stem cells depend on alterations in glutamine metabolism.

Kim JH, Lee KJ, Seo Y, Kwon JH, Yoon JP, Kang JY, Lee HJ, Park SJ, Hong SP, Cheon JH, Kim WH, Il Kim T. Kim JH, et al. Among authors: seo y. Sci Rep. 2018 Aug 28;8(1):13111. doi: 10.1038/s41598-018-29895-5. Sci Rep. 2018. PMID: 30154414 Free PMC article.

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MRI assessment of glutamine uptake correlates with the distribution of glutamine transporters and cancer stem cell markers.

Seo Y, Kang J, Kim TI, Joo CG. Seo Y, et al. Sci Rep. 2022 Apr 1;12(1):5511. doi: 10.1038/s41598-022-09529-7. Sci Rep. 2022. PMID: 35365739 Free PMC article.

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Tumor-Suppressive Effect of Metformin via the Regulation of M2 Macrophages and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment of Colorectal Cancer.

Kang J, Lee D, Lee KJ, Yoon JE, Kwon JH, Seo Y, Kim J, Chang SY, Park J, Kang EA, Park SJ, Park JJ, Cheon JH, Kim TI. Kang J, et al. Among authors: seo y. Cancers (Basel). 2022 Jun 10;14(12):2881. doi: 10.3390/cancers14122881. Cancers (Basel). 2022. PMID: 35740547 Free PMC article.

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Effects of metformin on colorectal cancer stem cells depend on alterations in glutamine metabolism.

Kim JH, Lee KJ, Seo Y, Kwon JH, Yoon JP, Kang JY, Lee HJ, Park SJ, Hong SP, Cheon JH, Kim WH, Il Kim T. Kim JH, et al. Among authors: seo y. Sci Rep. 2018 Jan 11;8(1):409. doi: 10.1038/s41598-017-18762-4. Sci Rep. 2018. PMID: 29323154 Free PMC article.

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