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2019 3
2020 5
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Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways.
Mizunoe Y, Kobayashi M, Sudo Y, Watanabe S, Yasukawa H, Natori D, Hoshino A, Negishi A, Okita N, Komatsu M, Higami Y. Mizunoe Y, et al. Redox Biol. 2018 May;15:115-124. doi: 10.1016/j.redox.2017.09.007. Epub 2017 Sep 20. Redox Biol. 2018. PMID: 29241092 Free PMC article.
The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice.
Araki M, Nakagawa Y, Oishi A, Han SI, Wang Y, Kumagai K, Ohno H, Mizunoe Y, Iwasaki H, Sekiya M, Matsuzaka T, Shimano H. Araki M, et al. Among authors: mizunoe y. Int J Mol Sci. 2018 Jul 23;19(7):2148. doi: 10.3390/ijms19072148. Int J Mol Sci. 2018. PMID: 30041488 Free PMC article.
Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice.
Matsuzaka T, Kuba M, Koyasu S, Yamamoto Y, Motomura K, Arulmozhiraja S, Ohno H, Sharma R, Shimura T, Okajima Y, Han SI, Aita Y, Mizunoe Y, Osaki Y, Iwasaki H, Yatoh S, Suzuki H, Sone H, Takeuchi Y, Yahagi N, Miyamoto T, Sekiya M, Nakagawa Y, Ema M, Takahashi S, Tokiwa H, Shimano H. Matsuzaka T, et al. Among authors: mizunoe y. Hepatology. 2020 May;71(5):1609-1625. doi: 10.1002/hep.30953. Epub 2020 Feb 7. Hepatology. 2020. PMID: 31529722
Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome.
Mizunoe Y, Kobayashi M, Tagawa R, Nakagawa Y, Shimano H, Higami Y. Mizunoe Y, et al. Int J Mol Sci. 2019 Jul 27;20(15):3688. doi: 10.3390/ijms20153688. Int J Mol Sci. 2019. PMID: 31357643 Free PMC article. Review.
Taurine is an amino acid with the ability to activate autophagy in adipocytes.
Kaneko H, Kobayashi M, Mizunoe Y, Yoshida M, Yasukawa H, Hoshino S, Itagawa R, Furuichi T, Okita N, Sudo Y, Imae M, Higami Y. Kaneko H, et al. Among authors: mizunoe y. Amino Acids. 2018 May;50(5):527-535. doi: 10.1007/s00726-018-2550-6. Epub 2018 Mar 9. Amino Acids. 2018. PMID: 29523960
Tbx1 regulates inherited metabolic and myogenic abilities of progenitor cells derived from slow- and fast-type muscle.
Motohashi N, Uezumi A, Asakura A, Ikemoto-Uezumi M, Mori S, Mizunoe Y, Takashima R, Miyagoe-Suzuki Y, Takeda S, Shigemoto K. Motohashi N, et al. Among authors: mizunoe y. Cell Death Differ. 2019 Jun;26(6):1024-1036. doi: 10.1038/s41418-018-0186-4. Epub 2018 Aug 28. Cell Death Differ. 2019. PMID: 30154444 Free PMC article.
Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism.
Sharma R, Matsuzaka T, Kaushik MK, Sugasawa T, Ohno H, Wang Y, Motomura K, Shimura T, Okajima Y, Mizunoe Y, Ma Y, Saber ZM, Iwasaki H, Yatoh S, Suzuki H, Aita Y, Han SI, Takeuchi Y, Yahagi N, Miyamoto T, Sekiya M, Nakagawa Y, Shimano H. Sharma R, et al. Among authors: mizunoe y. Sci Rep. 2019 Mar 26;9(1):5169. doi: 10.1038/s41598-019-41631-1. Sci Rep. 2019. PMID: 30914769 Free PMC article.
Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice.
Mizunoe Y, Sudo Y, Okita N, Hiraoka H, Mikami K, Narahara T, Negishi A, Yoshida M, Higashibata R, Watanabe S, Kaneko H, Natori D, Furuichi T, Yasukawa H, Kobayashi M, Higami Y. Mizunoe Y, et al. Autophagy. 2017 Apr 3;13(4):642-653. doi: 10.1080/15548627.2016.1274850. Epub 2017 Jan 25. Autophagy. 2017. PMID: 28121218 Free PMC article.
Inhibitory effect of p53 on mitochondrial content and function during adipogenesis.
Okita N, Ishikawa N, Mizunoe Y, Oku M, Nagai W, Suzuki Y, Matsushima S, Mikami K, Okado H, Sasaki T, Higami Y. Okita N, et al. Among authors: mizunoe y. Biochem Biophys Res Commun. 2014 Mar 28;446(1):91-7. doi: 10.1016/j.bbrc.2014.02.059. Epub 2014 Feb 21. Biochem Biophys Res Commun. 2014. PMID: 24565844
Srebp-1c/Fgf21/Pgc-1α Axis Regulated by Leptin Signaling in Adipocytes-Possible Mechanism of Caloric Restriction-Associated Metabolic Remodeling of White Adipose Tissue.
Kobayashi M, Uta S, Otsubo M, Deguchi Y, Tagawa R, Mizunoe Y, Nakagawa Y, Shimano H, Higami Y. Kobayashi M, et al. Among authors: mizunoe y. Nutrients. 2020 Jul 10;12(7):2054. doi: 10.3390/nu12072054. Nutrients. 2020. PMID: 32664386 Free PMC article.
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