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15 results

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Page 1
Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach.
Prakash M, Itoh Y, Fujiwara Y, Takahashi Y, Takada Y, Mellini P, Elboray EE, Terao M, Yamashita Y, Yamamoto C, Yamaguchi T, Kotoku M, Kitao Y, Singh R, Roy R, Obika S, Oba M, Wang DO, Suzuki T. Prakash M, et al. Among authors: kitao y. J Med Chem. 2021 Nov 11;64(21):15810-15824. doi: 10.1021/acs.jmedchem.1c01107. Epub 2021 Nov 3. J Med Chem. 2021. PMID: 34727689
Effect of matcha consumption on gut microbiota in healthy Japanese individuals: study protocol for a double-blind crossover interventional study.
Takegami M, Hamaguchi M, Miyoshi T, Munekawa C, Yoshimura T, Nakajima H, Kimura T, Okamura T, Hashimoto Y, Nakanishi N, Kitao Y, Kinoshita K, Fukui M. Takegami M, et al. Among authors: kitao y. J Clin Biochem Nutr. 2022 May;70(3):262-265. doi: 10.3164/jcbn.21-110. Epub 2021 Dec 3. J Clin Biochem Nutr. 2022. PMID: 35692672 Free PMC article.
Discovery of INT131: a selective PPARγ modulator that enhances insulin sensitivity.
Taygerly JP, McGee LR, Rubenstein SM, Houze JB, Cushing TD, Li Y, Motani A, Chen JL, Frankmoelle W, Ye G, Learned MR, Jaen J, Miao S, Timmermans PB, Thoolen M, Kearney P, Flygare J, Beckmann H, Weiszmann J, Lindstrom M, Walker N, Liu J, Biermann D, Wang Z, Hagiwara A, Iida T, Aramaki H, Kitao Y, Shinkai H, Furukawa N, Nishiu J, Nakamura M. Taygerly JP, et al. Among authors: kitao y. Bioorg Med Chem. 2013 Feb 15;21(4):979-92. doi: 10.1016/j.bmc.2012.11.058. Epub 2012 Dec 10. Bioorg Med Chem. 2013. PMID: 23294830
Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site.
Mellini P, Itoh Y, Elboray EE, Tsumoto H, Li Y, Suzuki M, Takahashi Y, Tojo T, Kurohara T, Miyake Y, Miura Y, Kitao Y, Kotoku M, Iida T, Suzuki T. Mellini P, et al. Among authors: kitao y. J Med Chem. 2019 Jun 27;62(12):5844-5862. doi: 10.1021/acs.jmedchem.9b00255. Epub 2019 Jun 12. J Med Chem. 2019. PMID: 31144814
15 results