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Page 1
Showing results for aiming geng
Search for Zaiming Geng instead (1 results)
Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy.
Li Q, Geng S, Luo H, Wang W, Mo YQ, Luo Q, Wang L, Song GB, Sheng JP, Xu B. Li Q, et al. Signal Transduct Target Ther. 2024 Oct 7;9(1):266. doi: 10.1038/s41392-024-01953-7. Signal Transduct Target Ther. 2024. PMID: 39370455 Free PMC article. Review.
In summary, our review captures the dynamic interplay between aberrant signaling in CRC pathogenesis and the concerted efforts to counteract these changes through targeted therapeutic strategies, ultimately aiming to pave the way for improved prognosis and personalized tre …
In summary, our review captures the dynamic interplay between aberrant signaling in CRC pathogenesis and the concerted efforts to counteract …
Precision treatment in advanced hepatocellular carcinoma.
Yang X, Yang C, Zhang S, Geng H, Zhu AX, Bernards R, Qin W, Fan J, Wang C, Gao Q. Yang X, et al. Cancer Cell. 2024 Feb 12;42(2):180-197. doi: 10.1016/j.ccell.2024.01.007. Cancer Cell. 2024. PMID: 38350421 Free article. Review.
This approach utilizes the unique molecular characteristics of individual patient to personalize treatment modalities, aiming to maximize therapeutic efficacy while minimizing side effects. Although precision treatment has shown significant success in multiple cancer types …
This approach utilizes the unique molecular characteristics of individual patient to personalize treatment modalities, aiming to maxi …
Mitochondrial quality control in human health and disease.
Liu BH, Xu CZ, Liu Y, Lu ZL, Fu TL, Li GR, Deng Y, Luo GQ, Ding S, Li N, Geng Q. Liu BH, et al. Mil Med Res. 2024 May 29;11(1):32. doi: 10.1186/s40779-024-00536-5. Mil Med Res. 2024. PMID: 38812059 Free PMC article. Review.
We also discuss agonists or antagonists targeting MQC, aiming to explore potential therapeutic and research prospects by enhancing MQC to stabilize mitochondrial function....
We also discuss agonists or antagonists targeting MQC, aiming to explore potential therapeutic and research prospects by enhancing MQ …
Association between different stages of cardiovascular-kidney-metabolic syndrome and the risk of all-cause mortality.
Li N, Li Y, Cui L, Shu R, Song H, Wang J, Chen S, Liu B, Shi H, Gao H, Huang T, Gao X, Geng T, Wu S. Li N, et al. Atherosclerosis. 2024 Oct;397:118585. doi: 10.1016/j.atherosclerosis.2024.118585. Epub 2024 Aug 30. Atherosclerosis. 2024. PMID: 39255681
However, the association between different stages of CKM syndrome and the risk of all-cause mortality remains unclear. This study aimed to evaluate the association between different stages of CKM syndrome and risk of all-cause mortality. ...The study emphasized the need fo …
However, the association between different stages of CKM syndrome and the risk of all-cause mortality remains unclear. This study aimed …
Genotypic and phenotypic characterization of Chinese patients with osteogenesis imperfecta.
Li L, Mao B, Li S, Xiao J, Wang H, Zhang J, Ren X, Wang Y, Wu Y, Cao Y, Lu C, Gao J, You Y, Zhao F, Geng X, Xiao Y, Jiang C, Ye Y, Yang T, Zhao X, Zhang X. Li L, et al. Hum Mutat. 2019 May;40(5):588-600. doi: 10.1002/humu.23718. Epub 2019 Feb 25. Hum Mutat. 2019. PMID: 30715774
This study presents a clinical characterization and mutation analysis of 668 patients, aiming to establish the mutation spectrum and to elucidate genotype-phenotype correlations in Chinese OI patients. ...
This study presents a clinical characterization and mutation analysis of 668 patients, aiming to establish the mutation spectrum and …
Mast Cells Initiate Type 2 Inflammation through Tryptase Released by MRGPRX2/MRGPRB2 Activation in Atopic Dermatitis.
Jia T, Che D, Zheng Y, Zhang H, Li Y, Zhou T, Peng B, Du X, Zhu L, An J, Geng S. Jia T, et al. J Invest Dermatol. 2024 Jan;144(1):53-62.e2. doi: 10.1016/j.jid.2023.06.201. Epub 2023 Jul 22. J Invest Dermatol. 2024. PMID: 37482287 Free article.
However, the role of MRGPRX2 in AD and the development of type 2 inflammation is not yet clear. This study aimed to define the role of MRGPRX2 in type 2 inflammation development and cytokine release in AD by determining its levels in patients with AD and healthy controls. …
However, the role of MRGPRX2 in AD and the development of type 2 inflammation is not yet clear. This study aimed to define the role o …
TRPA1 aggravates osteoclastogenesis and osteoporosis through activating endoplasmic reticulum stress mediated by SRXN1.
Zhu P, Tao H, Chen K, Chu M, Wang Q, Yang X, Zhou J, Yang H, Geng D. Zhu P, et al. Cell Death Dis. 2024 Aug 27;15(8):624. doi: 10.1038/s41419-024-07018-5. Cell Death Dis. 2024. PMID: 39191723 Free PMC article.
However, little research has focused on TRPA1 function in OP. As a result, this study aimed to explore the TRPA1 characteristics and its potential therapeutic function during osteoclastogenesis. ...
However, little research has focused on TRPA1 function in OP. As a result, this study aimed to explore the TRPA1 characteristics and …
GameBus on FHIR.
Geng C, Khanshan A, van Gorp P. Geng C, et al. Stud Health Technol Inform. 2024 Aug 22;316:1312-1313. doi: 10.3233/SHTI240653. Stud Health Technol Inform. 2024. PMID: 39176622
This study showcases the integration of a FHIR layer into GameBus, a gamified health platform, aiming to enhance its interoperability. Traditionally, GameBus has relied on proprietary data schemas and REST APIs, which restricted data exchange with other platforms. ...
This study showcases the integration of a FHIR layer into GameBus, a gamified health platform, aiming to enhance its interoperability …
[Skin mechanomedicine].
Geng SM, Hu JH, Zhao Q, Feng YQ, Wang X, Liu H, Xu F. Geng SM, et al. Zhonghua Yi Xue Za Zhi. 2025 Feb 18;105(7):489-496. doi: 10.3760/cma.j.cn112137-20240623-01393. Zhonghua Yi Xue Za Zhi. 2025. PMID: 39956624 Chinese.
Meanwhile, in-depth exploration was conducted on the potential application of mechanical factors in the diagnosis and treatment of skin diseases, aiming to provide new research perspectives and solutions for the diagnosis and treatment of skin diseases....
Meanwhile, in-depth exploration was conducted on the potential application of mechanical factors in the diagnosis and treatment of skin dise …
Gut microbiome dysregulation in noninfectious uveitis.
Liu M, Geng J, Liu T, Liu X. Liu M, et al. Front Immunol. 2025 Jul 29;16:1614304. doi: 10.3389/fimmu.2025.1614304. eCollection 2025. Front Immunol. 2025. PMID: 40799652 Free PMC article. Review.
Furthermore, possible therapeutic measures are discussed, including probiotics, prebiotics, dietary modifications, antibiotic interventions, as well as fecal microbial transplantation, aiming to exert beneficial effects on NIU progression by reshaping the gut microbial com …
Furthermore, possible therapeutic measures are discussed, including probiotics, prebiotics, dietary modifications, antibiotic interventions, …
2,576 results