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An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.
Chu H, Shuai H, Qiao J, Yoon C, Zhang G, Hou Y, Xia X, Wang L, Deng X, Wang Y, Li Q, Du L, Liu Y, Zhou M, Wong HT, Liu H, Hu B, Chen Y, Fang Z, Xia Z, Chai Y, Shi J, Wang Y, Zhu T, Zhang H, Yuan S, Zhou J, Chan J, Yuen KY, Xu C, Lei J, Yang S. Chu H, et al. Among authors: fang z. Res Sq [Preprint]. 2024 Nov 21:rs.3.rs-5454588. doi: 10.21203/rs.3.rs-5454588/v1. Res Sq. 2024. Update in: Nat Commun. 2025 Jul 16;16(1):6541. doi: 10.1038/s41467-025-60832-z. PMID: 39606435 Free PMC article. Updated. Preprint.
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.
Shuai H, Qiao J, Yoon C, Zhang G, Hou Y, Xia X, Wang L, Deng X, Wang Y, Li Q, Du L, Liu Y, Zhou M, Wong HT, Hu J, Liu H, Hu B, Wang D, Su J, Pan Y, Ye Y, Chen Y, Fang Z, Xia Z, Chai Y, Shi J, Wang Y, Zhu T, Zhang H, Yuan S, Zhou J, Chan JF, Yuen KY, Xu C, Lei J, Yang S, Chu H. Shuai H, et al. Among authors: fang z. Nat Commun. 2025 Jul 16;16(1):6541. doi: 10.1038/s41467-025-60832-z. Nat Commun. 2025. PMID: 40670362 Free PMC article.
411 results