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1

Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery.

Cukras C, Wiley HE, Jeffrey BG, Sen HN, Turriff A, Zeng Y, Vijayasarathy C, Marangoni D, Ziccardi L, Kjellstrom S, Park TK, Hiriyanna S, Wright JF, Colosi P, Wu Z, Bush RA, Wei LL, Sieving PA. Cukras C, et al. Among authors: Wu Z. Mol Ther. 2018 Sep 5;26(9):2282-2294. doi: 10.1016/j.ymthe.2018.05.025. Epub 2018 Jul 7. Mol Ther. 2018. PMID: 30196853 Free PMC article. Clinical Trial.

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2

Use of AAV Vectors for CRISPR-Mediated In Vivo Genome Editing in the Retina.

Yu W, Wu Z. Yu W, et al. Among authors: Wu Z. Methods Mol Biol. 2019;1950:123-139. doi: 10.1007/978-1-4939-9139-6_7. Methods Mol Biol. 2019. PMID: 30783971 Free PMC article.

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3

Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice.

Yu W, Mookherjee S, Chaitankar V, Hiriyanna S, Kim JW, Brooks M, Ataeijannati Y, Sun X, Dong L, Li T, Swaroop A, Wu Z. Yu W, et al. Among authors: Wu Z. Nat Commun. 2017 Mar 14;8:14716. doi: 10.1038/ncomms14716. Nat Commun. 2017. PMID: 28291770 Free PMC article.

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4

A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration.

Mookherjee S, Chen HY, Isgrig K, Yu W, Hiriyanna S, Levron R, Li T, Colosi P, Chien W, Swaroop A, Wu Z. Mookherjee S, et al. Among authors: Wu Z. Cell Rep. 2018 Oct 16;25(3):611-623.e6. doi: 10.1016/j.celrep.2018.09.043. Cell Rep. 2018. PMID: 30332642 Free PMC article.

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5

Molecular codes for cell type specification in Brn3 retinal ganglion cells.

Sajgo S, Ghinia MG, Brooks M, Kretschmer F, Chuang K, Hiriyanna S, Wu Z, Popescu O, Badea TC. Sajgo S, et al. Among authors: Wu Z. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E3974-E3983. doi: 10.1073/pnas.1618551114. Epub 2017 May 2. Proc Natl Acad Sci U S A. 2017. PMID: 28465430 Free PMC article.

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6

Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations.

Sun X, Park JH, Gumerson J, Wu Z, Swaroop A, Qian H, Roll-Mecak A, Li T. Sun X, et al. Among authors: Wu Z. Proc Natl Acad Sci U S A. 2016 May 24;113(21):E2925-34. doi: 10.1073/pnas.1523201113. Epub 2016 May 9. Proc Natl Acad Sci U S A. 2016. PMID: 27162334 Free PMC article.

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7

Preclinical Dose-Escalation Study of Intravitreal AAV-RS1 Gene Therapy in a Mouse Model of X-linked Retinoschisis: Dose-Dependent Expression and Improved Retinal Structure and Function.

Bush RA, Zeng Y, Colosi P, Kjellstrom S, Hiriyanna S, Vijayasarathy C, Santos M, Li J, Wu Z, Sieving PA. Bush RA, et al. Among authors: Wu Z. Hum Gene Ther. 2016 May;27(5):376-89. doi: 10.1089/hum.2015.142. Hum Gene Ther. 2016. PMID: 27036983 Free PMC article.

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8

Influence of the built environment of Nanjing's Urban Community on the leisure physical activity of the elderly: an empirical study.

Wu ZJ, Song Y, Wang HL, Zhang F, Li FH, Wang ZY. Wu ZJ, et al. BMC Public Health. 2019 Nov 6;19(1):1459. doi: 10.1186/s12889-019-7643-y. BMC Public Health. 2019. PMID: 31694592 Free PMC article.

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9

Some physicochemical aspects of water-soluble mineral flotation.

Wu Z, Wang X, Liu H, Zhang H, Miller JD. Wu Z, et al. Adv Colloid Interface Sci. 2016 Sep;235:190-200. doi: 10.1016/j.cis.2016.06.005. Epub 2016 Jun 10. Adv Colloid Interface Sci. 2016. PMID: 27346329 Review.

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10

In Vivo Applications of CRISPR-Based Genome Editing in the Retina.

Yu W, Wu Z. Yu W, et al. Among authors: Wu Z. Front Cell Dev Biol. 2018 May 14;6:53. doi: 10.3389/fcell.2018.00053. eCollection 2018. Front Cell Dev Biol. 2018. PMID: 29868583 Free PMC article. Review.

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