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The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy.
Yang B, Zhang B, Cao Z, Xu X, Huo Z, Zhang P, Xiang S, Zhao Z, Lv C, Meng M, Zhang G, Dong L, Shi S, Yang L, Zhou Q. Yang B, et al. Among authors: huo z. Cell Death Differ. 2020 Aug;27(8):2433-2450. doi: 10.1038/s41418-020-0514-3. Epub 2020 Mar 6. Cell Death Differ. 2020. PMID: 32144382 Free PMC article.
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