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The following term was not found in PubMed: zirian
Page 1
Showing results for zirian fu
Search for Zitian Fu instead (3 results)
Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells.
Yang C, Song J, Hwang S, Choi J, Song G, Lim W. Yang C, et al. Redox Biol. 2021 Nov;47:102144. doi: 10.1016/j.redox.2021.102144. Epub 2021 Sep 21. Redox Biol. 2021. PMID: 34562873 Free PMC article.
Although effective drugs have been developed, including 5-fluorouracil (5-FU), advanced colorectal cancer (CRC) shows low therapeutic sensitivity resulting from the development of 5-FU resistance. ...Among them, we found that apigenin enhanced the inhibitory effect …
Although effective drugs have been developed, including 5-fluorouracil (5-FU), advanced colorectal cancer (CRC) shows low therapeutic …
ERRATUM.
Furutani A, Sowa Y, Fujiwara H, Otsuji E, Sakai T. Furutani A, et al. Oncol Res. 2016 Jan 21;23(1):87. doi: 10.3727/096504016X14514194509664. Oncol Res. 2016. PMID: 29021025 Free PMC article.
Histone deacetylase (HDAC) inhibitors have been shown to enhance the effects of 5-fluorouracil (5-FU) against various cancer cells; however, no report has shown that an HDAC inhibitor may enhance the effects of 5-FU with radiation. Therefore, we investigated whether …
Histone deacetylase (HDAC) inhibitors have been shown to enhance the effects of 5-fluorouracil (5-FU) against various cancer cells; h …
Low miR-224-5p in exosomes confers colorectal cancer 5-FU resistance by upregulating S100A4.
Yan YY, Deng ZF, Wu XT, Lu Y, Zhu ZY, Wen Q, Zhang W, Zhang HY, Chen XZ, Wu YS, He XB, Ma ZA, Li JS, Bi H, Zhang JY. Yan YY, et al. Drug Resist Updat. 2025 Mar;79:101211. doi: 10.1016/j.drup.2025.101211. Epub 2025 Feb 6. Drug Resist Updat. 2025. PMID: 39956015
This study aimed to identify molecular markers that mediate 5-fluorouracil (5-FU) resistance in colorectal cancer (CRC). Exosomes from 5-FU resistant CRC cells (HCT-15/FU) significantly enhanced the resistance to 5-FU and the malignant properties of HC …
This study aimed to identify molecular markers that mediate 5-fluorouracil (5-FU) resistance in colorectal cancer (CRC). Exosomes fro …
5-FU Cardiotoxicity: Vasospasm, Myocarditis, and Sudden Death.
More LA, Lane S, Asnani A. More LA, et al. Curr Cardiol Rep. 2021 Feb 3;23(3):17. doi: 10.1007/s11886-021-01441-2. Curr Cardiol Rep. 2021. PMID: 33537861 Review.
PURPOSE OF REVIEW: 5-fluorouracil (5-FU) is one of the most common causes of cardiotoxicity associated with chemotherapy. ...Here we summarize the mechanistic and clinical data available to guide clinicians in caring for patients with suspected 5-FU cardiotoxicity. …
PURPOSE OF REVIEW: 5-fluorouracil (5-FU) is one of the most common causes of cardiotoxicity associated with chemotherapy. ...Here we …
Therapeutic drug monitoring of 5-fluorouracil.
Lee JJ, Beumer JH, Chu E. Lee JJ, et al. Cancer Chemother Pharmacol. 2016 Sep;78(3):447-64. doi: 10.1007/s00280-016-3054-2. Epub 2016 May 23. Cancer Chemother Pharmacol. 2016. PMID: 27217046 Free PMC article. Review.
However, it is now well established that BSA-based 5-FU dosing is correlated with a wide variation of 5-FU systemic exposure. Pharmacokinetic (PK) studies of 5-FU systemic exposure have shown a wide range of interpatient variation of 5-FU plasma drug l …
However, it is now well established that BSA-based 5-FU dosing is correlated with a wide variation of 5-FU systemic exposure. …
Review of 5-FU resistance mechanisms in colorectal cancer: clinical significance of attenuated on-target effects.
Gmeiner WH, Okechukwu CC. Gmeiner WH, et al. Cancer Drug Resist. 2023 Apr 29;6(2):257-272. doi: 10.20517/cdr.2022.136. eCollection 2023. Cancer Drug Resist. 2023. PMID: 37457133 Free PMC article. Review.
The causes of 5-FU resistance are multi-factorial, and besides DNA mismatch repair deficiency (MMR-D), there are no widely accepted criteria for determining which CRC patients are not likely to be responsive to 5-FU-based therapy. Thus, there is a need to systematic …
The causes of 5-FU resistance are multi-factorial, and besides DNA mismatch repair deficiency (MMR-D), there are no widely accepted c …
GLI2-HRD1 axis facilitates 5-FU resistance in gastric cancer cells by regulating ubiquitination degradation of UCK2.
Xue C, Zhang X, Yu W, Lin H, Zhang J, Liu J, Weng Z, Ouyang M, Lin X. Xue C, et al. Transl Oncol. 2025 Aug;58:102423. doi: 10.1016/j.tranon.2025.102423. Epub 2025 May 24. Transl Oncol. 2025. PMID: 40414119 Free PMC article.
5-Fluorouracil (5-FU) is a primary chemotherapeutic agent for treating gastric cancer (GC), yet resistance to 5-FU frequently limits its effectiveness and contributes to poor patient outcomes. ...Functional assays demonstrated that lowering UCK2 or increasing HRD1 e …
5-Fluorouracil (5-FU) is a primary chemotherapeutic agent for treating gastric cancer (GC), yet resistance to 5-FU frequently …
[Distinguishment of XU Qiu-fu's thirteen ghost points].
Xiong RH, Zhang SJ. Xiong RH, et al. Zhongguo Zhen Jiu. 2023 Jun 12;43(6):709-14. doi: 10.13703/j.0255-2930.20220504-k0006. Zhongguo Zhen Jiu. 2023. PMID: 37313567 Chinese.
In addition to the well-known thirteen ghost points in Qianjin Fang (Important Formulas worth a Thousand Gold Pieces), "XU Qiu-fu's thirteen ghost points" is recorded in other medical books. The contents of "XU Qiu-fu's thirteen ghost points" are not exactly same am …
In addition to the well-known thirteen ghost points in Qianjin Fang (Important Formulas worth a Thousand Gold Pieces), "XU Qiu-fu's t …
Should we still be using bolus 5-FU prior to infusional regimens in gastrointestinal cancers? A practical review.
Amorim LC, Peixoto RD. Amorim LC, et al. Int Cancer Conf J. 2021 Nov 24;11(1):2-5. doi: 10.1007/s13691-021-00526-7. eCollection 2022 Jan. Int Cancer Conf J. 2021. PMID: 35127313 Free PMC article. Review.
The true clinical value of bolus 5-FU right before infusional regimens remains to be determined since no randomized trials have addressed this issue. This manuscript aims to review the history of 5-FU, its mechanism of action and the data exploring the role of bolus …
The true clinical value of bolus 5-FU right before infusional regimens remains to be determined since no randomized trials have addre …
5-Fluorouracil-induced exacerbation of rosacea.
Haddock ES, Cohen PR. Haddock ES, et al. Dermatol Online J. 2016 Nov 15;22(11):13030/qt9n4377w6. Dermatol Online J. 2016. PMID: 28329576 Free article. Review.
Albeit rarely, exacerbation of rosacea by topical 5-FU treatment has been described when 5-FU was introduced as a topical treatment for actinic keratosis.Conclusion Topical 5-FU has been associated with several adverse cutaneous events, including accentuation …
Albeit rarely, exacerbation of rosacea by topical 5-FU treatment has been described when 5-FU was introduced as a topical trea …
221,633 results
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