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Page 1
Familial Cerebral Cavernous Malformations: Pathophysiology, Genetics, Biomarkers, and Treatment Perspectives.
Fontes-Dantas FL, da Fontoura Galvão G, Cunha AM, de Sena Murteira Pinheiro P, Morandi V, de Souza JM. Fontes-Dantas FL, et al. J Neurochem. 2026 Jan;170(1):e70342. doi: 10.1111/jnc.70342. J Neurochem. 2026. PMID: 41486746 Free PMC article. Review.
Complementing imaging, emerging circulating biomarkers, including inflammatory cytokines and plasma microRNAs associated with mutation status, may improve individualized risk stratification. This primer synthesizes current knowledge on FCCM pathophysiology, genetics, diagn …
Complementing imaging, emerging circulating biomarkers, including inflammatory cytokines and plasma microRNAs associated with mutation statu …
Thiopurine-methyltransferase variants in inflammatory bowel disease: prevalence and toxicity in Brazilian patients.
Carvalho AT, Esberard BC, Fróes RS, Rapozo DC, Grinman AB, Simão TA, Santos JC, Carneiro AJ, Ribeiro-Pinto LF, de Souza HS. Carvalho AT, et al. World J Gastroenterol. 2014 Mar 28;20(12):3327-34. doi: 10.3748/wjg.v20.i12.3327. World J Gastroenterol. 2014. PMID: 24696613 Free PMC article.
We analyzed the presence of major TPMT genetic variants (TPMT 2, 3A, 3C) in IBD patients by means of a specific allele and RFLP-PCR. Genomic DNA was isolated from peripheral blood leukocytes by proteinase-K/Sodium Dodecyl Sulfate digestion and phenol-chloroform extraction. …
We analyzed the presence of major TPMT genetic variants (TPMT 2, 3A, 3C) in IBD patients by means of a specific allele and RFLP-PCR. Genomic …
New isoforms of human mitochondrial transcription factor A detected in normal and tumoral cells.
De Virgilio C, Pousis C, Bruno S, Gadaleta G. De Virgilio C, et al. Mitochondrion. 2011 Mar;11(2):287-95. doi: 10.1016/j.mito.2010.10.009. Epub 2010 Nov 19. Mitochondrion. 2011. PMID: 21081181
Novel alternatively spliced variants of the human mitochondrial transcription factor A predicted by the computational tool ASPic were experimentally validated in different normal and tumoral human tissues by RT-PCR and DNA sequencing. The comparison between the 5'UTR lengt …
Novel alternatively spliced variants of the human mitochondrial transcription factor A predicted by the computational tool ASPic were experi …
Cloning of the sea urchin mitochondrial RNA polymerase and reconstitution of the transcription termination system.
Polosa PL, Deceglie S, Falkenberg M, Roberti M, Di Ponzio B, Gadaleta MN, Cantatore P. Polosa PL, et al. Nucleic Acids Res. 2007;35(7):2413-27. doi: 10.1093/nar/gkm159. Epub 2007 Mar 28. Nucleic Acids Res. 2007. PMID: 17392338 Free PMC article.
To investigate transcription termination in sea urchin mitochondria, we cloned the mitochondrial RNA polymerase (mtRNAP) of Paracentrotus lividus and used a recombinant form of the enzyme in a reconstituted transcription system, in the presence of the DNA-binding protein m …
To investigate transcription termination in sea urchin mitochondria, we cloned the mitochondrial RNA polymerase (mtRNAP) of Paracentrotus li …
Localization of abasic sites and single-strand breaks in mitochondrial DNA from brain of aged rat, treated or not with caloric restriction diet.
Lezza AM, Fallacara FP, Pesce V, Leeuwenburgh C, Cantatore P, Gadaleta MN. Lezza AM, et al. Neurochem Res. 2008 Dec;33(12):2609-14. doi: 10.1007/s11064-008-9866-7. Epub 2008 Oct 23. Neurochem Res. 2008. PMID: 18946734
According to the "mitochondrial theory of aging" the lifelong accumulation of various kinds of damage to mitochondrial DNA (mtDNA) has been related to the age-dependent mitochondrial bioenergetic dysfunction. ...
According to the "mitochondrial theory of aging" the lifelong accumulation of various kinds of damage to mitochondrial DNA (mtDNA) ha …
A multicenter study of confirmed COVID-19 cases: preliminary data on 2690 pediatric patients in Argentina during the first year of the pandemic.
Gentile Á, Juárez MDV, Romero Bollón L, Cancellara AD, Pasinovich M, Brizuela M, Euliarte C, Ensinck GN, Russ C, Saraceni L, Tapponier G, Villa Nova S, Falaschi A, Garnero A, Melonari P, Bellone L, Gaiano A, Pebe Florian V, Bogdanowicz E, Areso MS; Red de Pediatría COVID-19. Gentile Á, et al. Arch Argent Pediatr. 2022 Apr;120(2):80-88. doi: 10.5546/aap.2022.eng.80. Epub 2021 Dec 3. Arch Argent Pediatr. 2022. PMID: 35338811 Free article. English, Spanish.
A convective polymerase chain reaction (CPCR) coupled with NALF immunoassays as a rapid detection strategy for Listeria monocytogenes in pork meat.
López AMF, Rosas RIA, Cervera VF, Ramírez RR, Lerma AGV, Almanza AFC, Soto EUC. López AMF, et al. J Microbiol Methods. 2025 Sep;236:107209. doi: 10.1016/j.mimet.2025.107209. Epub 2025 Aug 4. J Microbiol Methods. 2025. PMID: 40754009
A specific amplification was obtained with a correctly designed primer, showing amplification only where the L. monocytogenes DNA was used. No amplification was obtained with other pathogens, including Listeria innocua and Listeria ivanovii. ...Samples MC6, MC28, MC …
A specific amplification was obtained with a correctly designed primer, showing amplification only where the L. monocytogenes DNA …