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Multiple modes of action of hydrophobic amines and their guanidine analogues on ASIC1a.
Shteinikov VY, Barygin OI, Gmiro VE, Tikhonov DB. Shteinikov VY, et al. Eur J Pharmacol. 2019 Feb 5;844:183-194. doi: 10.1016/j.ejphar.2018.12.024. Epub 2018 Dec 14. Eur J Pharmacol. 2019. PMID: 30557561
Hydrophobic monoamines containing only a hydrophobic/aromatic moiety and protonated amino group are a recently described class of acid-sensing ion channel (ASIC) modulators. Intensive studies have revealed a number of active compounds including endogenous amines and pharma …
Hydrophobic monoamines containing only a hydrophobic/aromatic moiety and protonated amino group are a recently described class of acid-sensi …
Hydrophobic Amines and Their Guanidine Analogues Modulate Activation and Desensitization of ASIC3.
Shteinikov VY, Potapieva NN, Gmiro VE, Tikhonov DB. Shteinikov VY, et al. Int J Mol Sci. 2019 Apr 6;20(7):1713. doi: 10.3390/ijms20071713. Int J Mol Sci. 2019. PMID: 30959896 Free PMC article.
Acid-sensing ion channel 3 (ASIC3) is an important member of the acid-sensing ion channels family, which is widely expressed in the peripheral nervous system and contributes to pain sensation. ...
Acid-sensing ion channel 3 (ASIC3) is an important member of the acid-sensing ion channels family, which is widely expressed i …