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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1986 1
1989 3
1990 1
1991 1
1992 2
1993 2
1994 1
1995 2
1996 3
1998 3
1999 1
2000 6
2001 3
2002 10
2003 11
2004 6
2005 8
2006 9
2007 7
2008 13
2009 12
2010 13
2011 8
2012 17
2013 11
2014 25
2015 28
2016 30
2017 28
2018 26
2019 34
2020 51
2021 38
2022 46
2023 41
2024 9

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461 results

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Page 1
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies.
Galon J, Bruni D. Galon J, et al. Nat Rev Drug Discov. 2019 Mar;18(3):197-218. doi: 10.1038/s41573-018-0007-y. Nat Rev Drug Discov. 2019. PMID: 30610226 Review.
The impact of combination therapy on the immune response to convert an immune cold into a hot tumour will be discussed....
The impact of combination therapy on the immune response to convert an immune cold into a hot tumour will be discussed....
Applications of Digital PCR for Clinical Microbiology.
Kuypers J, Jerome KR. Kuypers J, et al. J Clin Microbiol. 2017 Jun;55(6):1621-1628. doi: 10.1128/JCM.00211-17. Epub 2017 Mar 15. J Clin Microbiol. 2017. PMID: 28298452 Free PMC article. Review.
Its advantages over quantitative PCR (qPCR), including absolute quantification without a standard curve, improved precision, improved accuracy in the presence of inhibitors, and more accurate quantitation when amplification efficiency is low, make dPCR the assay of choice for sev …
Its advantages over quantitative PCR (qPCR), including absolute quantification without a standard curve, improved precision, improved accura …
Alzheimer's disease associated with Down syndrome: a genetic form of dementia.
Fortea J, Zaman SH, Hartley S, Rafii MS, Head E, Carmona-Iragui M. Fortea J, et al. Lancet Neurol. 2021 Nov;20(11):930-942. doi: 10.1016/S1474-4422(21)00245-3. Lancet Neurol. 2021. PMID: 34687637 Free PMC article. Review.
Unprecedented research activity in Down syndrome is rapidly changing this bleak scenario that will translate into disease-modifying therapies that could benefit other populations....
Unprecedented research activity in Down syndrome is rapidly changing this bleak scenario that will translate into disease-modifying t …
Immunoscore and its introduction in clinical practice.
Galon J, Lanzi A. Galon J, et al. Q J Nucl Med Mol Imaging. 2020 Jun;64(2):152-161. doi: 10.23736/S1824-4785.20.03249-5. Epub 2020 Feb 27. Q J Nucl Med Mol Imaging. 2020. PMID: 32107902 Free article. Review.
In additional analyses, we showed the prognostic value of Immunoscore for stage II-IV CRC patients, as well as the predictive value of Immunoscore in stage III colon cancer patients. The Immunoscore may help predict and stratify patients who will benefit from adjuvant chem …
In additional analyses, we showed the prognostic value of Immunoscore for stage II-IV CRC patients, as well as the predictive value of Immun …
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease.
Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, Ping L, Duong DM, Epstein MP, McDade E, Barthélemy NR, Karch CM, Xiong C, Cruchaga C, Perrin RJ, Wingo AP, Wingo TS, Chhatwal JP, Day GS, Noble JM, Berman SB, Martins R, Graff-Radford NR, Schofield PR, Ikeuchi T, Mori H, Levin J, Farlow M, Lah JJ, Haass C, Jucker M, Morris JC, Benzinger TLS, Roberts BR, Bateman RJ, Fagan AM, Seyfried NT, Levey AI; Dominantly Inherited Alzheimer Network. Johnson ECB, et al. Nat Med. 2023 Aug;29(8):1979-1988. doi: 10.1038/s41591-023-02476-4. Epub 2023 Aug 7. Nat Med. 2023. PMID: 37550416 Free PMC article.
Our results highlight the multifaceted landscape of AD pathophysiology and its temporal evolution. Such knowledge will be critical for developing precision therapeutic interventions and biomarkers for AD beyond those associated with Abeta and tau....
Our results highlight the multifaceted landscape of AD pathophysiology and its temporal evolution. Such knowledge will be critical fo …
Leptomeningeal Metastases.
Graber JJ, Kesari S. Graber JJ, et al. Curr Treat Options Oncol. 2018 Jan 23;19(1):3. doi: 10.1007/s11864-018-0518-0. Curr Treat Options Oncol. 2018. PMID: 29362920 Review.
Options for intrathecal therapies are expanding, but physicians should be mindful that this is a passive delivery system that relies on normal CSF flow, so therapies will not penetrate bulky or parenchymal disease sites, especially in the presence of abnormal CSF flow. Whe …
Options for intrathecal therapies are expanding, but physicians should be mindful that this is a passive delivery system that relies on norm …
Primary aldosteronism.
Funder J. Funder J. Trends Cardiovasc Med. 2022 May;32(4):228-233. doi: 10.1016/j.tcm.2021.03.005. Epub 2021 Mar 26. Trends Cardiovasc Med. 2022. PMID: 33775861 Review.
In 1955 Dr Jerome Conn first documented primary aldosteronism (PA). Since then, screening, diagnosis and treatment have developed, in the process both refining and complicating management. ...The front-line actors need to be Internists/Primary Care Providers; the costs …
In 1955 Dr Jerome Conn first documented primary aldosteronism (PA). Since then, screening, diagnosis and treatment have developed, in …
Detection and Management of Amyloid-Related Imaging Abnormalities in Patients with Alzheimer's Disease Treated with Anti-Amyloid Beta Therapy.
Barakos J, Purcell D, Suhy J, Chalkias S, Burkett P, Marsica Grassi C, Castrillo-Viguera C, Rubino I, Vijverberg E. Barakos J, et al. J Prev Alzheimers Dis. 2022;9(2):211-220. doi: 10.14283/jpad.2022.21. J Prev Alzheimers Dis. 2022. PMID: 35542992 Review.
Given the availability of an anti-Abeta therapy, ARIA monitoring will now be implemented in routine clinical practice. The simple magnetic resonance imaging sequences used in clinical trials are likely sufficient for effective detection of cases. ...
Given the availability of an anti-Abeta therapy, ARIA monitoring will now be implemented in routine clinical practice. The simple mag …
L’immunothérapie dans les cancers ORL.
Reverdy T, Gau M, Karabajakian A, Neidhardt EM, Fayette J. Reverdy T, et al. Bull Cancer. 2018 Dec;105 Suppl 1:S35-S42. doi: 10.1016/S0007-4551(18)30388-6. Bull Cancer. 2018. PMID: 30595197 Review. French.
Multiple clinical studies are in progress in both palliative and curative intent, combined or not with other checkpoint inhibitor (anti-CTLA4) or other standard therapies (radiotherapy, chemotherapy). It is essential to define which patients will benefit from immunotherapy …
Multiple clinical studies are in progress in both palliative and curative intent, combined or not with other checkpoint inhibitor (anti-CTLA …
Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis.
Nissen SE, Yeomans ND, Solomon DH, Lüscher TF, Libby P, Husni ME, Graham DY, Borer JS, Wisniewski LM, Wolski KE, Wang Q, Menon V, Ruschitzka F, Gaffney M, Beckerman B, Berger MF, Bao W, Lincoff AM; PRECISION Trial Investigators. Nissen SE, et al. N Engl J Med. 2016 Dec 29;375(26):2519-29. doi: 10.1056/NEJMoa1611593. Epub 2016 Nov 13. N Engl J Med. 2016. PMID: 27959716 Free article. Clinical Trial.
461 results