Chikungunya virus arthritis in adult wild-type mice.
Gardner J, Anraku I, Le TT, Larcher T, Major L, Roques P, Schroder WA, Higgs S, Suhrbier A.
Gardner J, et al. Among authors: major l.
J Virol. 2010 Aug;84(16):8021-32. doi: 10.1128/JVI.02603-09. Epub 2010 Jun 2.
J Virol. 2010.
PMID: 20519386
Free PMC article.
IFN-alpha treatment was able to prevent arthritis only if given before infection, suggesting that IFN-alpha is not a viable therapy. Prior infection with Ross River virus, a related arthrogenic alphavirus, and anti-Ross River virus antibodies protected mice against chikung …
IFN-alpha treatment was able to prevent arthritis only if given before infection, suggesting that IFN-alpha is not a viable therapy. …