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Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Wang X, Huang S, Zhang M, Su Y, Pan Z, Liang J, Xie X, Wang Q, Chen J, Zhou L, Luo X. Wang X, et al. J Ethnopharmacol. 2023 Feb 10;302(Pt B):115919. doi: 10.1016/j.jep.2022.115919. Epub 2022 Nov 7. J Ethnopharmacol. 2023. PMID: 36356716
ETHNOPHARMACOLOGICAL RELEVANCE: Gegen Qinlian decoction (GQD) is a traditional Chinese medicine derived from Treatise on febrile diseases and is clinically used for the treatment of acute ulcerative colitis (UC). ...
ETHNOPHARMACOLOGICAL RELEVANCE: Gegen Qinlian decoction (GQD) is a traditional Chinese medicine derived from Treatise on febrile dise …
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Wang Y, Zhang J, Zhang B, Lu M, Ma J, Liu Z, Huang J, Ma J, Yang X, Wang F, Tang X. Wang Y, et al. J Ethnopharmacol. 2023 Sep 15;313:116538. doi: 10.1016/j.jep.2023.116538. Epub 2023 Apr 21. J Ethnopharmacol. 2023. PMID: 37086872
ETHNOPHARMACOLOGICAL RELEVANCE: Modified Gegen Qinlian decoction (MGQD), which was first documented in Treatise on Febrile Disease, is recognized as a classic prescription to treat ulcerative colitis (UC). ...
ETHNOPHARMACOLOGICAL RELEVANCE: Modified Gegen Qinlian decoction (MGQD), which was first documented in Treatise on Febrile Disease, i …
Modified Gegen Qinlian decoction ameliorates DSS-induced chronic colitis in mice by restoring the intestinal mucus barrier and inhibiting the activation of gammadeltaT17 cells.
Ma J, Zhang J, Wang Y, Huang J, Yang X, Ma J, Liu Z, Wang F, Tang X. Ma J, et al. Phytomedicine. 2023 Mar;111:154660. doi: 10.1016/j.phymed.2023.154660. Epub 2023 Jan 12. Phytomedicine. 2023. PMID: 36681051 Free article.
BACKGROUND: Current therapeutics for ulcerative colitis (UC) have limitations. Classical Formula Gegen Qinlian decoction (GQD) is derived from Shang Han Lun and has a long history of treating gastrointestinal diseases such as diarrhea and UC. ...
BACKGROUND: Current therapeutics for ulcerative colitis (UC) have limitations. Classical Formula Gegen Qinlian decoction (GQD) is der …
Chinese Medicine in the Treatment of Ulcerative Colitis: The Mechanisms of Signaling Pathway Regulations.
Zheng S, Xue T, Wang B, Guo H, Liu Q. Zheng S, et al. Am J Chin Med. 2022;50(7):1781-1798. doi: 10.1142/S0192415X22500756. Epub 2022 Aug 11. Am J Chin Med. 2022. PMID: 35950375 Review.
Commonly used traditional Chinese medicines for the treatment of UC include Caulis Sargentodoxae, Flos Lonicerae, Fructus Cnidii, etc. Additionally, classic prescriptions such as Gegen Qinlian Formulae and Zuojin Pills can also be used to treat UC. To enrich the traditiona …
Commonly used traditional Chinese medicines for the treatment of UC include Caulis Sargentodoxae, Flos Lonicerae, Fructus Cnidii, etc. Addit …
Main active components of Jiawei Gegen Qinlian decoction protects against ulcerative colitis under different dietary environments in a gut microbiota-dependent manner.
Li Q, Cui Y, Xu B, Wang Y, Lv F, Li Z, Li H, Chen X, Peng X, Chen Y, Wu E, Qu D, Jian Y, Si H. Li Q, et al. Pharmacol Res. 2021 Aug;170:105694. doi: 10.1016/j.phrs.2021.105694. Epub 2021 Jun 2. Pharmacol Res. 2021. PMID: 34087350
At present, the effectiveness and mechanism of Jiawei Gegen Qinlian decoction against UC in different dietary environments are not clear. Here, the main active components of Jiawei Gegen Qinlian Decoction (PBM), were selected to construct a reasonable and effective …
At present, the effectiveness and mechanism of Jiawei Gegen Qinlian decoction against UC in different dietary environments are not cl …
Antidiabetic Effects of Gegen Qinlian Decoction via the Gut Microbiota Are Attributable to Its Key Ingredient Berberine.
Xu X, Gao Z, Yang F, Yang Y, Chen L, Han L, Zhao N, Xu J, Wang X, Ma Y, Shu L, Hu X, Lyu N, Pan Y, Zhu B, Zhao L, Tong X, Wang J. Xu X, et al. Genomics Proteomics Bioinformatics. 2020 Dec;18(6):721-736. doi: 10.1016/j.gpb.2019.09.007. Epub 2020 Dec 24. Genomics Proteomics Bioinformatics. 2020. PMID: 33359679 Free PMC article.
Gegen Qinlian Decoction (GQD), a traditional Chinese medicine (TCM) formula, has long been used for the treatment of common metabolic diseases, including type 2 diabetes mellitus. ...
Gegen Qinlian Decoction (GQD), a traditional Chinese medicine (TCM) formula, has long been used for the treatment of common metabolic …
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
Wang X, Quan J, Xiu C, Wang J, Zhang J. Wang X, et al. Chin Med. 2023 Aug 30;18(1):110. doi: 10.1186/s13020-023-00819-4. Chin Med. 2023. PMID: 37649073 Free PMC article.
BACKGROUND: Gegen Qinlian decoction (GQD) is a classic prescription for treating ulcerative colitis (UC) in traditional Chinese medicine. ...
BACKGROUND: Gegen Qinlian decoction (GQD) is a classic prescription for treating ulcerative colitis (UC) in traditional Chinese medic …
Based on Network Pharmacology to Explore the Molecular Targets and Mechanisms of Gegen Qinlian Decoction for the Treatment of Ulcerative Colitis.
Wei M, Li H, Li Q, Qiao Y, Ma Q, Xie R, Wang R, Liu Y, Wei C, Li B, Zheng C, Sun B, Yu B. Wei M, et al. Biomed Res Int. 2020 Nov 24;2020:5217405. doi: 10.1155/2020/5217405. eCollection 2020. Biomed Res Int. 2020. PMID: 33299870 Free PMC article.
BACKGROUND: Gegen Qinlian (GGQL) decoction is a common Chinese herbal compound for the treatment of ulcerative colitis (UC). ...
BACKGROUND: Gegen Qinlian (GGQL) decoction is a common Chinese herbal compound for the treatment of ulcerative colitis (UC). ...
Qinlian hongqu decoction ameliorates hyperlipidemia via the IRE1-alpha/IKKB-beta/NF-kappab signaling pathway: Network pharmacology and experimental validation.
Zhang Y, Guo Z, Wang J, Yue Y, Yang Y, Wen Y, Luo Y, Zhang X. Zhang Y, et al. J Ethnopharmacol. 2024 Jan 10;318(Pt A):116856. doi: 10.1016/j.jep.2023.116856. Epub 2023 Jul 3. J Ethnopharmacol. 2024. PMID: 37406747
ETHNOPHARMACOLOGICAL RELEVANCE: Qinlian Hongqu decoction (QLHQD) is a traditional Chinese medicine (TCM) formula. ...
ETHNOPHARMACOLOGICAL RELEVANCE: Qinlian Hongqu decoction (QLHQD) is a traditional Chinese medicine (TCM) formula. ...
Gegen Qinlian Decoction treatment of asymptomatic hyperuricemia by targeting circadian immune function.
Wang X, Liu X, Gao Q, Gu X, Zhang G, Sheng Z, Wu T, Su Z, Wang W, Ye M. Wang X, et al. Chin Med. 2023 Jun 27;18(1):77. doi: 10.1186/s13020-023-00775-z. Chin Med. 2023. PMID: 37370132 Free PMC article.
BACKGROUND: The Gegen Qinlian Decoction (GGQLD) is a renowned traditional Chinese medicinal formula that has been used for centuries to effectively treat asymptomatic Hyperuricemia (HUA). ...
BACKGROUND: The Gegen Qinlian Decoction (GGQLD) is a renowned traditional Chinese medicinal formula that has been used for centuries …
79 results