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1958 3
1959 1
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1962 1
1963 1
1964 4
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1966 7
1967 6
1968 6
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1970 4
1971 7
1972 7
1973 5
1974 7
1975 27
1976 32
1977 25
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1980 26
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1984 25
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1986 23
1987 35
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1989 51
1990 44
1991 49
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1995 72
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2003 105
2004 90
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2013 275
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Page 1
Subclinical hyperthyroidism in children.
Metwalley KA, Farghaly HS. Metwalley KA, et al. J Pediatr Endocrinol Metab. 2022 Dec 6;36(4):342-345. doi: 10.1515/jpem-2022-0534. Print 2023 Apr 25. J Pediatr Endocrinol Metab. 2022. PMID: 36473171 Review.
Depending on the degree of TSH suppression, SH could be defined as mild (TSH, 0.1-0.45 mU/L) or severe (TSH<0.1 mU/L). Patients with SH are often asymptomatic when symptoms are present, they are similar to the symptoms in patients with overt hyperth …
Depending on the degree of TSH suppression, SH could be defined as mild (TSH, 0.1-0.45 mU/L) or severe (TSH<0.1 mU/L …
Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage.
Sun ZW, Zhang L, Zhu SJ, Chen WC, Mei B. Sun ZW, et al. Neurosci Bull. 2010 Feb;26(1):8-16. doi: 10.1007/s12264-010-0813-7. Neurosci Bull. 2010. PMID: 20101268 Free PMC article.
OBJECTIVE: To investigate the mechanisms of excitotoxic effects of glutamate on human neuroblastoma SH-SY5Y cells. METHODS: SH-SY5Y cell viability was measured by MTT assay. Other damaged profile was detected by lactate dehydrogenase (LDH) release and by 4', 6-diami …
OBJECTIVE: To investigate the mechanisms of excitotoxic effects of glutamate on human neuroblastoma SH-SY5Y cells. METHODS: SH …
Endoplasmic reticulum stress regulates oxygen-glucose deprivation-induced parthanatos in human SH-SY5Y cells via improvement of intracellular ROS.
Wang HF, Wang ZQ, Ding Y, Piao MH, Feng CS, Chi GF, Luo YN, Ge PF. Wang HF, et al. CNS Neurosci Ther. 2018 Jan;24(1):29-38. doi: 10.1111/cns.12771. Epub 2017 Oct 16. CNS Neurosci Ther. 2018. PMID: 29045036 Free PMC article.
METHODS: we used oxygen-glucose deprivation (OGD) and human SH-SY5Y cells to simulate neuronal damage caused by ischemia. RESULTS: Oxygen-glucose deprivation induced time-dependent death in SH-SY5Y cells, which was accompanied with upregulation of PARP-1, accumulati …
METHODS: we used oxygen-glucose deprivation (OGD) and human SH-SY5Y cells to simulate neuronal damage caused by ischemia. RESULTS: Ox …
Liposomal Form of L-Dopa and SH-Sy5y Cell-Derived Exosomes Modulate the Tyrosine Hydroxylase/Dopamine Receptor D2 Signaling Pathway in Parkinson's Rat Models.
Zarrin P, Dehghani Ashkezari M, Seifati SM. Zarrin P, et al. J Mol Neurosci. 2021 Dec;71(12):2583-2592. doi: 10.1007/s12031-021-01853-3. Epub 2021 Jun 14. J Mol Neurosci. 2021. PMID: 34125397
This study aimed to evaluate the potential effects of exosomes released from SH-Sy5y cells and the liposomal form of L-dopa on Parkinson's rat models. Twenty-five male Wistar albino rats, in five groups, were included in this study. Parkinson's disease was induced t …
This study aimed to evaluate the potential effects of exosomes released from SH-Sy5y cells and the liposomal form of L-dopa on …
Exploring the therapeutic potential of Rab11: A comprehensive study on its effectiveness in alleviating rotenone-induced molecular pathogenesis of Parkinson's disease in SH-SY5Y cells and its synergistic application with L-DOPA in Drosophila models.
Rai P, Pandey SN, Roy JK. Rai P, et al. Int J Biol Macromol. 2024 Apr;263(Pt 1):130219. doi: 10.1016/j.ijbiomac.2024.130219. Epub 2024 Feb 16. Int J Biol Macromol. 2024. PMID: 38367785
Our study explored whether activating mitophagy triggers the unfolded protein response and ER stress pathway in SH-SY5Y human cells. We induced a PD-like state by exposing undifferentiated SH-SY5Y cells to rotenone, an established PD-inducing agent. ...It also provi …
Our study explored whether activating mitophagy triggers the unfolded protein response and ER stress pathway in SH-SY5Y human cells. …
Monocarboxylate Transporters 1 and 2 Are Responsible for L-Lactate Uptake in Differentiated Human Neuroblastoma SH-SY5Y Cells.
Sakuma T, Mukai Y, Yamaguchi A, Suganuma Y, Okamoto K, Furugen A, Narumi K, Ishikawa S, Saito Y, Kobayashi M. Sakuma T, et al. Biol Pharm Bull. 2024;47(4):764-770. doi: 10.1248/bpb.b23-00860. Biol Pharm Bull. 2024. PMID: 38569835 Free article.
L-Lactate uptake was measured using radiolabeled L-lactate, and the expression of MCT proteins was confirmed Western blotting. ...In this study, we demonstrated that MCT1 and 2 are major contributors to L-lactate transport in differentiated human neuroblastom …
L-Lactate uptake was measured using radiolabeled L-lactate, and the expression of MCT proteins was confirmed Western blotting. …
The Interactions Between Aligned Poly(L-Lactic Acid) Nanofibers and SH-SY5Y Cells In Vitro.
Yu Y, Meng D, Man L, Wang X. Yu Y, et al. J Nanosci Nanotechnol. 2016 Jun;16(6):6407-13. doi: 10.1166/jnn.2016.10883. J Nanosci Nanotechnol. 2016. PMID: 27427727
In this study, we explored the effects of electrospun Poly(L-Lactic Acid) (PLLA) aligned nanofibers on SH-SY5Y cells (a type of human neuroblastoma cell line) and specifically focused on the role of integrin in the PLLA aligned nanofiber-SH-SY5Y cell interact …
In this study, we explored the effects of electrospun Poly(L-Lactic Acid) (PLLA) aligned nanofibers on SH-SY5Y cells (a type o …
The effect of L-thyroxine treatment on ventricular dysfunction and pulmonary arterial stiffness in patients with subclinical hypothyroidism.
Çamci S, Yilmaz E, Yakarişik M. Çamci S, et al. Eur Rev Med Pharmacol Sci. 2022 Oct;26(19):7036-7045. doi: 10.26355/eurrev_202210_29887. Eur Rev Med Pharmacol Sci. 2022. PMID: 36263551 Free article.
RESULTS: The mean age of patients in the SH group was 44.1 9.4 years and 47.1% were women. Euthyroidism in SH patients was achieved with a mean daily L-thyroxine treatment of 59 g/day for a mean of 16.1 4.5 weeks. ...While PAS was 16.9 3.1 kHz/ms in the contr …
RESULTS: The mean age of patients in the SH group was 44.1 9.4 years and 47.1% were women. Euthyroidism in SH patients was ach …
Carnitine Protects against MPP(+)-Induced Neurotoxicity and Inflammation by Promoting Primary Ciliogenesis in SH-SY5Y Cells.
Bae JE, Kim JB, Jo DS, Park NY, Kim YH, Lee HJ, Kim SH, Kim SH, Son M, Kim P, Ryu HY, Lee WH, Ryoo ZY, Lee HS, Jung YK, Cho DH. Bae JE, et al. Cells. 2022 Sep 1;11(17):2722. doi: 10.3390/cells11172722. Cells. 2022. PMID: 36078130 Free PMC article.
Moreover, we performed fecal metabolite screening in order to identify several candidates for improving primary ciliogenesis, including L-carnitine and acetyl-L-carnitine. However, the role of carnitine in primary ciliogenesis has remained unclear. ...In this study, …
Moreover, we performed fecal metabolite screening in order to identify several candidates for improving primary ciliogenesis, including L …
Cathepsin L is involved in 6-hydroxydopamine induced apoptosis of SH-SY5Y neuroblastoma cells.
Xiang B, Fei X, Zhuang W, Fang Y, Qin Z, Liang Z. Xiang B, et al. Brain Res. 2011 Apr 28;1387:29-38. doi: 10.1016/j.brainres.2011.02.092. Epub 2011 Mar 5. Brain Res. 2011. PMID: 21382360
In this study we detected the changes in the expression of lysosomal cathepsin L in cellular models of PD. In human neuroblastoma SH-SY5Y cells, treatment with 6-hydroxydopamine caused an increase in cathepsin L immunoreactivity in the cytoplasm and an increa …
In this study we detected the changes in the expression of lysosomal cathepsin L in cellular models of PD. In human neuroblastoma …
10,620 results
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