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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1951 2
1962 2
1963 1
1964 2
1965 1
1966 1
1967 3
1968 2
1969 1
1971 1
1973 5
1974 3
1975 3
1976 2
1977 6
1978 1
1979 8
1980 5
1981 2
1982 3
1983 7
1984 7
1985 5
1986 3
1987 2
1988 14
1989 10
1990 10
1991 6
1992 17
1993 19
1994 13
1995 19
1996 12
1997 23
1998 13
1999 18
2000 17
2001 20
2002 16
2003 12
2004 17
2005 16
2006 13
2007 13
2008 22
2009 23
2010 16
2011 21
2012 19
2013 27
2014 33
2015 27
2016 41
2017 29
2018 29
2019 35
2020 40
2021 32
2022 29
2023 33
2024 13

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784 results

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Page 1
RNA granules: functional compartments or incidental condensates?
Putnam A, Thomas L, Seydoux G. Putnam A, et al. Genes Dev. 2023 May 1;37(9-10):354-376. doi: 10.1101/gad.350518.123. Epub 2023 May 3. Genes Dev. 2023. PMID: 37137715 Free PMC article. Review.
RNA granules are mesoscale assemblies that form in the absence of limiting membranes. RNA granules contain factors for RNA biogenesis and turnover and are often assumed to represent specialized compartments for RNA biochemistry. ...
RNA granules are mesoscale assemblies that form in the absence of limiting membranes. RNA granules contain factors for RNA bio …
G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.
Kedersha N, Panas MD, Achorn CA, Lyons S, Tisdale S, Hickman T, Thomas M, Lieberman J, McInerney GM, Ivanov P, Anderson P. Kedersha N, et al. J Cell Biol. 2016 Mar 28;212(7):845-60. doi: 10.1083/jcb.201508028. J Cell Biol. 2016. PMID: 27022092 Free PMC article.
Mammalian stress granules (SGs) contain stalled translation preinitiation complexes that are assembled into discrete granules by specific RNA-binding proteins such as G3BP. ...
Mammalian stress granules (SGs) contain stalled translation preinitiation complexes that are assembled into discrete granules …
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G; Genomics England Research Consortium; de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. Prentzell MT, et al. Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25. Cell. 2021. PMID: 33497611 Free PMC article.
Ras GTPase-activating protein-binding proteins 1 and 2 (G3BP1 and G3BP2, respectively) are widely recognized as core components of stress granules (SGs). We report that G3BPs reside at the cytoplasmic surface of lysosomes. ...
Ras GTPase-activating protein-binding proteins 1 and 2 (G3BP1 and G3BP2, respectively) are widely recognized as core components of stress …
Mast Cell Biology at Molecular Level: a Comprehensive Review.
Elieh Ali Komi D, Wöhrl S, Bielory L. Elieh Ali Komi D, et al. Clin Rev Allergy Immunol. 2020 Jun;58(3):342-365. doi: 10.1007/s12016-019-08769-2. Clin Rev Allergy Immunol. 2020. PMID: 31828527 Review.
Mast cells (MCs) are portions of the innate and adaptive immune system derived from bone marrow (BM) progenitors that are rich in cytoplasmic granules. MC maturation, phenotype, and function are determined by their microenvironment. ...The final consequence of such …
Mast cells (MCs) are portions of the innate and adaptive immune system derived from bone marrow (BM) progenitors that are rich in cytopla …
Stress Granules Determine the Development of Obesity-Associated Pancreatic Cancer.
Fonteneau G, Redding A, Hoag-Lee H, Sim ES, Heinrich S, Gaida MM, Grabocka E. Fonteneau G, et al. Cancer Discov. 2022 Aug 5;12(8):1984-2005. doi: 10.1158/2159-8290.CD-21-1672. Cancer Discov. 2022. PMID: 35674408 Free PMC article.
Previous work has identified the phase-separation organelles, stress granules (SG), as mutant KRAS-dependent mediators of stress adaptation. ...
Previous work has identified the phase-separation organelles, stress granules (SG), as mutant KRAS-dependent mediators of stress adap …
CSF-to-dura gateways.
Thomas JL, Benveniste H. Thomas JL, et al. J Exp Med. 2023 Feb 6;220(2):e20221719. doi: 10.1084/jem.20221719. Epub 2022 Dec 6. J Exp Med. 2023. PMID: 36472584 Free PMC article.
Postmortem microstructural studies together with in vivo magnetic resonance imaging show that human arachnoid granulations are porous channels that serve as transient filtration conduits for cerebrospinal fluid to flow directly into dural interstitial tissue, but not into …
Postmortem microstructural studies together with in vivo magnetic resonance imaging show that human arachnoid granulations are porous …
Lsm7 phase-separated condensates trigger stress granule formation.
Lindström M, Chen L, Jiang S, Zhang D, Gao Y, Zheng J, Hao X, Yang X, Kabbinale A, Thoma J, Metzger LC, Zhang DY, Zhu X, Liu H, Gustafsson CM, Burmann BM, Winderickx J, Sunnerhagen P, Liu B. Lindström M, et al. Nat Commun. 2022 Jun 28;13(1):3701. doi: 10.1038/s41467-022-31282-8. Nat Commun. 2022. PMID: 35764627 Free PMC article.
Stress granules (SGs) are non-membranous organelles facilitating stress responses and linking the pathology of age-related diseases. ...
Stress granules (SGs) are non-membranous organelles facilitating stress responses and linking the pathology of age-related diseases. …
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Mackenzie IR, Nicholson AM, Sarkar M, Messing J, Purice MD, Pottier C, Annu K, Baker M, Perkerson RB, Kurti A, Matchett BJ, Mittag T, Temirov J, Hsiung GR, Krieger C, Murray ME, Kato M, Fryer JD, Petrucelli L, Zinman L, Weintraub S, Mesulam M, Keith J, Zivkovic SA, Hirsch-Reinshagen V, Roos RP, Züchner S, Graff-Radford NR, Petersen RC, Caselli RJ, Wszolek ZK, Finger E, Lippa C, Lacomis D, Stewart H, Dickson DW, Kim HJ, Rogaeva E, Bigio E, Boylan KB, Taylor JP, Rademakers R. Mackenzie IR, et al. Neuron. 2017 Aug 16;95(4):808-816.e9. doi: 10.1016/j.neuron.2017.07.025. Neuron. 2017. PMID: 28817800 Free PMC article.
TIA1 mutations significantly increased the propensity of TIA1 protein to undergo phase transition. In live cells, TIA1 mutations delayed stress granule (SG) disassembly and promoted the accumulation of non-dynamic SGs that harbored TDP-43. ...
TIA1 mutations significantly increased the propensity of TIA1 protein to undergo phase transition. In live cells, TIA1 mutations delayed str …
Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation.
Wang C, Duan Y, Duan G, Wang Q, Zhang K, Deng X, Qian B, Gu J, Ma Z, Zhang S, Guo L, Liu C, Fang Y. Wang C, et al. Mol Cell. 2020 Aug 6;79(3):443-458.e7. doi: 10.1016/j.molcel.2020.06.019. Epub 2020 Jul 9. Mol Cell. 2020. PMID: 32649883 Free article.
Finally, we discover that the ALS-associated mutation D169G impairs the NEAT1-mediated TDP-43 LLPS and NB assembly, causing excessive cytoplasmic translocation of TDP-43 to form stress granules, which become phosphorylated TDP-43 cytoplasmic foci upon prolong …
Finally, we discover that the ALS-associated mutation D169G impairs the NEAT1-mediated TDP-43 LLPS and NB assembly, causing excessive cyt …
Factors contributing to the potency of CD8+ T cells.
Sykulev Y. Sykulev Y. Trends Immunol. 2023 Sep;44(9):693-700. doi: 10.1016/j.it.2023.07.005. Epub 2023 Aug 7. Trends Immunol. 2023. PMID: 37558570 Review.
Here, I contemplate the molecular mechanisms controlling the sensitivity and kinetics of granule-mediated CD8(+) T cell cytolytic responses. I posit that the clustering of MHC-I molecules and T cell receptors (TCRs) on the cell surface, as well as the contribution of the C …
Here, I contemplate the molecular mechanisms controlling the sensitivity and kinetics of granule-mediated CD8(+) T cell cytolytic res …
784 results