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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1930 1
1931 2
1942 1
1943 2
1945 9
1947 1
1948 1
1949 5
1950 1
1952 1
1959 3
1960 1
1962 3
1963 2
1964 1
1965 1
1967 4
1968 1
1969 1
1970 1
1971 4
1972 5
1973 4
1974 7
1975 3
1976 8
1977 5
1978 8
1979 9
1980 16
1981 9
1982 16
1983 15
1984 28
1985 27
1986 109
1987 127
1988 157
1989 175
1990 165
1991 192
1992 220
1993 223
1994 253
1995 226
1996 380
1997 474
1998 459
1999 570
2000 618
2001 683
2002 587
2003 703
2004 564
2005 671
2006 830
2007 915
2008 1107
2009 1185
2010 1327
2011 1412
2012 1568
2013 1849
2014 2277
2015 2547
2016 2660
2017 2784
2018 3096
2019 3251
2020 3983
2021 4347
2022 4938
2023 4699
2024 5471
2025 6292
2026 2103

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60,087 results

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The following term was not found in PubMed: uifei
Page 1
Exercise and hyperuricemia: an opinion article.
Zhang T, Liu W, Gao S. Zhang T, et al. Ann Med. 2024 Dec;56(1):2396075. doi: 10.1080/07853890.2024.2396075. Epub 2024 Aug 26. Ann Med. 2024. PMID: 39183708 Free PMC article.
Implementing a scientifically informed fitness diet in conjunction with appropriate exercise may decrease HUA. Unfortunately, there is currently a shortfall in exercise intervention trials for individuals suffering from HUA. ...This opinion article analyses the caus …
Implementing a scientifically informed fitness diet in conjunction with appropriate exercise may decrease HUA. Unfortunately, there i …
Gut microbiota dysbiosis in hyperuricaemia promotes renal injury through the activation of NLRP3 inflammasome.
Zhou X, Ji S, Chen L, Liu X, Deng Y, You Y, Wang M, He Q, Peng B, Yang Y, Chen X, Kwan HY, Zhou L, Chen J, Zhao X. Zhou X, et al. Microbiome. 2024 Jun 21;12(1):109. doi: 10.1186/s40168-024-01826-9. Microbiome. 2024. PMID: 38907332 Free PMC article.
However, the role and underlying mechanism of the gut microbiota in HUA-induced renal injury remain unknown. RESULTS: A HUA rat model was first established by knocking out the uricase (UOX). ...A metabolomic analysis showed evident accumulation of gut-derived uremic …
However, the role and underlying mechanism of the gut microbiota in HUA-induced renal injury remain unknown. RESULTS: A HUA ra …
Association between triglyceride glucose index and hyperuricemia: a new evidence from China and the United States.
Gou R, Dou D, Tian M, Chang X, Zhao Y, Meng X, Li G. Gou R, et al. Front Endocrinol (Lausanne). 2024 Jul 1;15:1403858. doi: 10.3389/fendo.2024.1403858. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 39010899 Free PMC article.
BACKGROUND: Hyperuricemia (HUA) is a glo\bal public health problem. The etiology of HUA is complex and efficient and accurate assessment metrics are still lacking when conducting large-scale epidemiologic screening. ...CONCLUSION: These findings suggest that TyG, Ty …
BACKGROUND: Hyperuricemia (HUA) is a glo\bal public health problem. The etiology of HUA is complex and efficient and accurate …
Gut microbiota remodeling: A promising therapeutic strategy to confront hyperuricemia and gout.
Wang Z, Li Y, Liao W, Huang J, Liu Y, Li Z, Tang J. Wang Z, et al. Front Cell Infect Microbiol. 2022 Aug 10;12:935723. doi: 10.3389/fcimb.2022.935723. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36034697 Free PMC article. Review.
Structural changes or imbalance in the gut microbiota could cause metabolic disorders and participate in the synthesis of purine-metabolizing enzymes and the release of inflammatory cytokines, which is closely related to the occurrence and development of the metabolic immune dise …
Structural changes or imbalance in the gut microbiota could cause metabolic disorders and participate in the synthesis of purine-metabolizin …
High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling.
Xie D, Zhao H, Lu J, He F, Liu W, Yu W, Wang Q, Hisatome I, Yamamoto T, Koyama H, Cheng J. Xie D, et al. Am J Physiol Endocrinol Metab. 2021 Jun 1;320(6):E1032-E1043. doi: 10.1152/ajpendo.00518.2020. Epub 2021 Apr 26. Am J Physiol Endocrinol Metab. 2021. PMID: 33900847 Free article.
Overexpression of the lipogenic enzymes fatty acid synthase and acetyl-CoA carboxylase 1 was via activation of JNK, which was blocked by the JNK inhibitor SP600125. HUA activated AP-1 to upregulate lipogenic gene expression via JNK activation. In addition, HUA cause …
Overexpression of the lipogenic enzymes fatty acid synthase and acetyl-CoA carboxylase 1 was via activation of JNK, which was blocked by the …
Elucidating the role of gut microbiota dysbiosis in hyperuricemia and gout: Insights and therapeutic strategies.
Singh AK, Durairajan SSK, Iyaswamy A, Williams LL. Singh AK, et al. World J Gastroenterol. 2024 Oct 28;30(40):4404-4410. doi: 10.3748/wjg.v30.i40.4404. World J Gastroenterol. 2024. PMID: 39494101 Free PMC article. Review.
Hyperuricemia (HUA) is a condition associated with a high concentration of uric acid (UA) in the bloodstream and can cause gout and chronic kidney disease. ...Some studies have suggested that changes in the composition, diversity, and activity of microbes play a key role i …
Hyperuricemia (HUA) is a condition associated with a high concentration of uric acid (UA) in the bloodstream and can cause gout and c …
Demographic, regional and temporal trends of hyperuricemia epidemics in mainland China from 2000 to 2019: a systematic review and meta-analysis.
Li Y, Shen Z, Zhu B, Zhang H, Zhang X, Ding X. Li Y, et al. Glob Health Action. 2021 Jan 1;14(1):1874652. doi: 10.1080/16549716.2021.1874652. Glob Health Action. 2021. PMID: 33475474 Free PMC article.
BACKGROUND: Hyperuricemia (HUA) is becoming a global public health problem and associated with multiple diseases. ...CONCLUSIONS: The last two decades witnessed the rapid growth prevalence of HUA in China. Early screening and personalized health education for HUA …
BACKGROUND: Hyperuricemia (HUA) is becoming a global public health problem and associated with multiple diseases. ...CONCLUSIONS: The …
Prevalence and Risk Factors of Hyperuricemia and Gout: A Cross-sectional Survey from 31 Provinces in Mainland China.
Song J, Jin C, Shan Z, Teng W, Li J. Song J, et al. J Transl Int Med. 2022 Jul 7;10(2):134-145. doi: 10.2478/jtim-2022-0031. eCollection 2022 Jun. J Transl Int Med. 2022. PMID: 35959454 Free PMC article.
BACKGROUND AND OBJETIVES: Hyperuricemia (HUA) and gout seriously influence patients' quality of life. The current study was performed to investigate the prevalence of HUA and gout and the related risk factors in Chinese adults. ...The prevalence of HUA in mal …
BACKGROUND AND OBJETIVES: Hyperuricemia (HUA) and gout seriously influence patients' quality of life. The current study was performed …
Prediction and causal inference of hyperuricemia using gut microbiota.
Miyajima Y, Karashima S, Mizoguchi R, Kawakami M, Ogura K, Ogai K, Koshida A, Ikagawa Y, Ami Y, Zhu Q, Tsujiguchi H, Hara A, Kurihara S, Arakawa H, Nakamura H, Tamai I, Nambo H, Okamoto S. Miyajima Y, et al. Sci Rep. 2024 Apr 30;14(1):9901. doi: 10.1038/s41598-024-60427-6. Sci Rep. 2024. PMID: 38688923 Free PMC article.
Prolonged HUA is often associated with hypertension, atherosclerosis, diabetes mellitus, and chronic kidney disease. ...We obtained GM data through 16S rRNA-based sequencing of the fecal samples, finding that alpha-diversity by Shannon index was significantly low in the …
Prolonged HUA is often associated with hypertension, atherosclerosis, diabetes mellitus, and chronic kidney disease. ...We obtained G …
Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.
Fu Y, Chen YS, Xia DY, Luo XD, Luo HT, Pan J, Ma WQ, Li JZ, Mo QY, Tu Q, Li MM, Zhao Y, Li Y, Huang YT, Chen ZX, Li ZJ, Bernard L, Dione M, Zhang YM, Miao K, Chen JY, Zhu SS, Ren J, Zhou LJ, Jiang XZ, Chen J, Lin ZP, Chen JP, Ye H, Cao QY, Zhu YW, Yang L, Wang X, Wang WC. Fu Y, et al. NPJ Biofilms Microbiomes. 2024 Mar 20;10(1):25. doi: 10.1038/s41522-024-00486-9. NPJ Biofilms Microbiomes. 2024. PMID: 38509085 Free PMC article.
In this study, we constructed a novel model of HUA in geese and investigated the mechanism by which Lactobacillus rhamnosus GG (LGG) could have beneficial effects on HUA. ...Our findings demonstrated the potential of a goose model of diet-induced HUA, and LGG …
In this study, we constructed a novel model of HUA in geese and investigated the mechanism by which Lactobacillus rhamnosus GG (LGG) …
60,087 results
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