Similar articles for PMID: 18272495

Year	Number of Results
1994	1
1996	1
1997	1
1999	1
2000	2
2002	1
2003	1
2005	1
2006	4
2007	2
2008	8
2009	9
2010	9
2011	7
2012	9
2013	13
2014	14
2015	12
2016	3
2017	5
2018	9
2019	3
2020	3
2021	12
2022	4

1

Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn.

Mezo AR, McDonnell KA, Hehir CA, Low SC, Palombella VJ, Stattel JM, Kamphaus GD, Fraley C, Zhang Y, Dumont JA, Bitonti AJ. Mezo AR, et al. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2337-42. doi: 10.1073/pnas.0708960105. Epub 2008 Feb 12. Proc Natl Acad Sci U S A. 2008. PMID: 18272495 Free PMC article.

2

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity.

Abdiche YN, Yeung YA, Chaparro-Riggers J, Barman I, Strop P, Chin SM, Pham A, Bolton G, McDonough D, Lindquist K, Pons J, Rajpal A. Abdiche YN, et al. MAbs. 2015;7(2):331-43. doi: 10.1080/19420862.2015.1008353. MAbs. 2015. PMID: 25658443 Free PMC article.

3

Discovery and structure-activity relationships of small molecules that block the human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction.

Wang Z, Fraley C, Mezo AR. Wang Z, et al. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1253-6. doi: 10.1016/j.bmcl.2013.01.014. Epub 2013 Jan 11. Bioorg Med Chem Lett. 2013. PMID: 23375228

4

Qualification of a homogeneous cell-based neonatal Fc receptor (FcRn) binding assay and its application to studies on Fc functionality of IgG-based therapeutics.

Mathur A, Arora T, Liu L, Crouse-Zeineddini J, Mukku V. Mathur A, et al. J Immunol Methods. 2013 Apr 30;390(1-2):81-91. doi: 10.1016/j.jim.2013.01.011. Epub 2013 Feb 4. J Immunol Methods. 2013. PMID: 23384837

5

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.

Smith B, Kiessling A, Lledo-Garcia R, Dixon KL, Christodoulou L, Catley MC, Atherfold P, D'Hooghe LE, Finney H, Greenslade K, Hailu H, Kevorkian L, Lightwood D, Meier C, Munro R, Qureshi O, Sarkar K, Shaw SP, Tewari R, Turner A, Tyson K, West S, Shaw S, Brennan FR. Smith B, et al. MAbs. 2018 Oct;10(7):1111-1130. doi: 10.1080/19420862.2018.1505464. Epub 2018 Sep 12. MAbs. 2018. PMID: 30130439 Free PMC article.

6

Neonatal Fc receptor (FcRn): a novel target for therapeutic antibodies and antibody engineering.

Wang Y, Tian Z, Thirumalai D, Zhang X. Wang Y, et al. J Drug Target. 2014 May;22(4):269-78. doi: 10.3109/1061186X.2013.875030. Epub 2014 Jan 9. J Drug Target. 2014. PMID: 24404896 Review.

7

Characterization and screening of IgG binding to the neonatal Fc receptor.

Neuber T, Frese K, Jaehrling J, Jäger S, Daubert D, Felderer K, Linnemann M, Höhne A, Kaden S, Kölln J, Tiller T, Brocks B, Ostendorp R, Pabst S. Neuber T, et al. MAbs. 2014 Jul-Aug;6(4):928-42. doi: 10.4161/mabs.28744. Epub 2014 Apr 7. MAbs. 2014. PMID: 24802048 Free PMC article.

8

Structure-activity relationships of a peptide inhibitor of the human FcRn:human IgG interaction.

Mezo AR, McDonnell KA, Castro A, Fraley C. Mezo AR, et al. Bioorg Med Chem. 2008 Jun 15;16(12):6394-405. doi: 10.1016/j.bmc.2008.05.004. Epub 2008 May 6. Bioorg Med Chem. 2008. PMID: 18501614

9

Identification of human IgG1 variant with enhanced FcRn binding and without increased binding to rheumatoid factor autoantibody.

Maeda A, Iwayanagi Y, Haraya K, Tachibana T, Nakamura G, Nambu T, Esaki K, Hattori K, Igawa T. Maeda A, et al. MAbs. 2017 Jul;9(5):844-853. doi: 10.1080/19420862.2017.1314873. Epub 2017 Apr 7. MAbs. 2017. PMID: 28387635 Free PMC article.

10

Engineering human IgG1 affinity to human neonatal Fc receptor: impact of affinity improvement on pharmacokinetics in primates.

Yeung YA, Leabman MK, Marvin JS, Qiu J, Adams CW, Lien S, Starovasnik MA, Lowman HB. Yeung YA, et al. J Immunol. 2009 Jun 15;182(12):7663-71. doi: 10.4049/jimmunol.0804182. J Immunol. 2009. PMID: 19494290 Free article.

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