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Randomized non-comparative phase II trial of nivolumab plus paclitaxel in subjects with recurrent/metastatic head and neck squamous cell carcinoma unable for cisplatin-based chemotherapy. NIVOTAX TTCC study.
Docampo LI, Basté N, Oliva M, Carral A, Pérez Segura P, Medina-Colmenero A, Cirauqui B, Arrazubi V, Martínez Trufero J, Gutiérrez Calderón V, García Castaño A, Rubió-Casadevall J, Del Barco E, Basterretxea L, Bruixola G, Cabellos RÁ, Flor MJ, Braña I, Caballero J, Martínez J, Lambea J, Perez-Martin X, Montalbán C, Duran M, Mesia R; TTCC (Grupo Español de Tratamiento deTumores de Cabeza y Cuello). Docampo LI, et al. Eur J Cancer. 2026 Jun 18;241:116775. doi: 10.1016/j.ejca.2026.116775. Epub 2026 May 6. Eur J Cancer. 2026. PMID: 42107346 Free article. Clinical Trial.
BACKGROUND: Patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) who are ineligible for cisplatin have limited treatment options, and the role of chemoimmunotherapy in this population remains unexplored. METHODS: NIVOTAX was a randomized, …
BACKGROUND: Patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) who are ineligible for cisplatin …
Pulsed wind-driven control of phytoplankton biomass at a groundwater-enriched nearshore environment.
Basterretxea G, Font-Muñoz JS, Kane M, Regaudie-de-Gioux A, Satta CT, Tuval I. Basterretxea G, et al. Sci Total Environ. 2024 Dec 10;955:177123. doi: 10.1016/j.scitotenv.2024.177123. Epub 2024 Oct 21. Sci Total Environ. 2024. PMID: 39442725 Free article.
Chl near the shoreline was markedly higher than offshore (3.55 1.29 and 0.68 0.27 mg m(-3) respectively) but recurrently fluctuated in the afternoon to up to >7 mg m(-3). ...
Chl near the shoreline was markedly higher than offshore (3.55 1.29 and 0.68 0.27 mg m(-3) respectively) but recurrently fluctuat …
Experimental and Numerical Modeling of Aerosol Delivery for Preterm Infants.
Aramendia I, Fernandez-Gamiz U, Lopez-Arraiza A, Rey-Santano C, Mielgo V, Basterretxea FJ, Sancho J, Gomez-Solaetxe MA. Aramendia I, et al. Int J Environ Res Public Health. 2018 Feb 28;15(3):423. doi: 10.3390/ijerph15030423. Int J Environ Res Public Health. 2018. PMID: 29495619 Free PMC article.
In the case of FC75, the cumulative mass fraction for particles above 10 m was considerable higher with a driving pressure of 5 bar. These numerical models could be a helpful tool to assist parametric studies of new non-invasive devices for the treatment of RDS in preterm …
In the case of FC75, the cumulative mass fraction for particles above 10 m was considerable higher with a driving pressure of 5 bar. …
Undertreatment and overtreatment in older patients treated with chemotherapy.
Feliu J, Espinosa E, Basterretxea L, Paredero I, Llabrés E, Jiménez-Munárriz B, Antonio-Rebollo M, Losada B, Pinto A, Gironés R, Custodio AB, Muñoz MDM, Gómez-Mediavilla J, Torregrosa MD, Soler G, Cruz P, Higuera O, Molina-Garrido MJ. Feliu J, et al. J Geriatr Oncol. 2021 Apr;12(3):381-387. doi: 10.1016/j.jgo.2020.10.010. Epub 2020 Oct 24. J Geriatr Oncol. 2021. PMID: 33109485
Enantioselective Ring-Opening Polymerization of rac-Lactide Dictated by Densely Substituted Amino Acids.
Sanchez-Sanchez A, Rivilla I, Agirre M, Basterretxea A, Etxeberria A, Veloso A, Sardon H, Mecerreyes D, Cossío FP. Sanchez-Sanchez A, et al. J Am Chem Soc. 2017 Apr 5;139(13):4805-4814. doi: 10.1021/jacs.6b13080. Epub 2017 Mar 22. J Am Chem Soc. 2017. PMID: 28272877
Both diastereoisomers not only showed the ability to synthesize enriched isotactic polylactide with a P(m) higher than 0.90 at room temperature but also were able to preferentially promote the polymerization of one of the isomers (l or d) with respect to the other. ...
Both diastereoisomers not only showed the ability to synthesize enriched isotactic polylactide with a P(m) higher than 0.90 at room t …
Experimental Evaluation of Perfluorocarbon Aerosol Generation with Two Novel Nebulizer Prototypes.
Aramendia I, Fernandez-Gamiz U, Lopez-Arraiza A, Rey-Santano C, Mielgo V, Basterretxea FJ, Sancho J, Gomez-Solaetxe MA. Aramendia I, et al. Pharmaceutics. 2019 Jan 5;11(1):19. doi: 10.3390/pharmaceutics11010019. Pharmaceutics. 2019. PMID: 30621300 Free PMC article.
The results showed that both prototypes produced heterodisperse aerosols with Da mean values in all cases below 5 m. The initial experiments with distilled water showed MMAD values lower than 9 m and up to 15 m with prototype 1 and prototype 2, respectivel …
The results showed that both prototypes produced heterodisperse aerosols with Da mean values in all cases below 5 m. The initial exp …
Development and Validation of an Early Mortality Risk Score for Older Patients Treated with Chemotherapy for Cancer.
Feliu J, Pinto A, Basterretxea L, López-San Vicente B, Paredero I, Llabrés E, Jiménez-Munárriz B, Antonio-Rebollo M, Losada B, Espinosa E, Gironés R, Custodio AB, Muñoz MDM, Díaz-Almirón M, Gómez-Mediavilla J, Torregrosa MD, Soler G, Cruz P, Higuera O, González-Montalvo JI, Molina-Garrido MJ. Feliu J, et al. J Clin Med. 2021 Apr 10;10(8):1615. doi: 10.3390/jcm10081615. J Clin Med. 2021. PMID: 33920250 Free PMC article.

Results: In the training cohort, the independent predictors of 6-month mortality were metastatic stage (OR 4.8, 95% CI [2.4-9.6]), ECOG-PS 2 (OR 2.3, 95% CI [1.1-5.2]), ADL 5 (OR 1.7, 95% CI [1.1-3.5]), serum albumin levels 3.5 g/dL (OR 3.4, 95% CI [1.7-6.6]), BMI < 23 kg/

…
Results: In the training cohort, the independent predictors of 6-month mortality were metastatic stage (OR 4.8, 95% CI [2.4-9.6]), ECOG-PS 2 …
Settlement and post-settlement survival rates of the white seabream (Diplodus sargus) in the western Mediterranean Sea.
Cuadros A, Basterretxea G, Cardona L, Cheminée A, Hidalgo M, Moranta J. Cuadros A, et al. PLoS One. 2018 Jan 11;13(1):e0190278. doi: 10.1371/journal.pone.0190278. eCollection 2018. PLoS One. 2018. PMID: 29324758 Free PMC article.
The settlement period extended from early May to late June and maximum juvenile densities at the sampling sites varied between 5 and 11 ind. m-1 with maximum values observed in late May simultaneously occurring in the two coasts. ...
The settlement period extended from early May to late June and maximum juvenile densities at the sampling sites varied between 5 and 11 ind. …
In vitro surfactant and perfluorocarbon aerosol deposition in a neonatal physical model of the upper conducting airways.
Goikoetxea E, Murgia X, Serna-Grande P, Valls-i-Soler A, Rey-Santano C, Rivas A, Antón R, Basterretxea FJ, Miñambres L, Méndez E, Lopez-Arraiza A, Larrabe-Barrena JL, Gomez-Solaetxe MA. Goikoetxea E, et al. PLoS One. 2014 Sep 11;9(9):e106835. doi: 10.1371/journal.pone.0106835. eCollection 2014. PLoS One. 2014. PMID: 25211475 Free PMC article.
RESULTS: The nebulization system produced relatively large amounts of aerosol ranging between 0.3 0.0 ml/min for surfactant at a driving pressure of 4 bar, and 2.0 0.1 ml/min for distilled water (H2Od) at 6 bar, with MMADs between 2.61 0.1 m for PFD at 7 bar and 10.18 0.4 …
RESULTS: The nebulization system produced relatively large amounts of aerosol ranging between 0.3 0.0 ml/min for surfactant at a driving pre …