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Concurrent initiation of tirzepatide and biologics improves patient-reported outcomes in obese psoriatic arthritis: a propensity score-matched study.
Venerito V, Lopalco G, Colaprico C, Catamerò D, Cacciapaglia F, Iannone F. Venerito V, et al. RMD Open. 2026 Jul 30;12(3):e006830. doi: 10.1136/rmdopen-2026-006830. RMD Open. 2026. PMID: 42532547 Free PMC article.
The tirzepatide group showed greater BMI reduction (-2.9 2.0 vs +0.4 1.2 kg/m2, p<0.001) and lower CRP (4.2 3.8 vs 7.7 3.0 mg/L, p<0.001). PsAID-12 PASS was achieved by 48% vs 21% (OR 3.44, 95% CI 1.38 to 8.63, p=0.009), HAQ 0.5 by 42% vs 18% (OR …
The tirzepatide group showed greater BMI reduction (-2.9 2.0 vs +0.4 1.2 kg/m2, p<0.001) and lower CRP (4.2 3.8 vs 7.7 3.0 mg/L …
Correlation of Serum Amyloid-A Levels, Clinical Manifestations, Treatment, and Disease Activity in Patients with Behçet's Disease.
Sota J, Vitale A, Rigante D, Orlando I, Lucherini OM, Simpatico A, Lopalco G, Franceschini R, Galeazzi M, Frediani B, Fabiani C, Tosi GM, Cantarini L. Sota J, et al. Isr Med Assoc J. 2018 Aug;20(8):517-521. Isr Med Assoc J. 2018. PMID: 30084580 Free article.

RESULTS: No association was identified between SAA levels and BD disease activity (Spearman's rho = 0.085, P = 0.411). A significant difference was found in the mean BDCAF score between patients presenting with SAA levels < 200 mg/L and those with SAA levels >

…
RESULTS: No association was identified between SAA levels and BD disease activity (Spearman's rho = 0.085, P = 0.411). A significant …
Risk of acute arterial and venous thromboembolic events in eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome).
Bettiol A, Sinico RA, Schiavon F, Monti S, Bozzolo EP, Franceschini F, Govoni M, Lunardi C, Guida G, Lopalco G, Paolazzi G, Vacca A, Gregorini G, Leccese P, Piga M, Conti F, Fraticelli P, Quartuccio L, Alberici F, Salvarani C, Bettio S, Negrini S, Selmi C, Sciascia S, Moroni G, Colla L, Manno C, Urban ML, Vannacci A, Pozzi MR, Fabbrini P, Polti S, Felicetti M, Marchi MR, Padoan R, Delvino P, Caporali R, Montecucco C, Dagna L, Cariddi A, Toniati P, Tamanini S, Furini F, Bortoluzzi A, Tinazzi E, Delfino L, Badiu I, Rolla G, Venerito V, Iannone F, Berti A, Bortolotti R, Racanelli V, Jeannin G, Padula A, Cauli A, Priori R, Gabrielli A, Bond M, Tedesco M, Pazzola G, Tomietto P, Pellecchio M, Marvisi C, Maritati F, Palmisano A, Dejaco C, Willeit J, Kiechl S, Olivotto I, Willeit P, Prisco D, Vaglio A, Emmi G; Italian EGPA Consortium. Bettiol A, et al. Eur Respir J. 2021 May 6;57(5):2004158. doi: 10.1183/13993003.04158-2020. Print 2021 May. Eur Respir J. 2021. PMID: 33833031 Free article. No abstract available.
A snapshot of subcutaneous infliximab uses in inflammatory rheumatic diseases: a multicentric Italian study.
Gentileschi S, Gaggiano C, Placido F, Terribili R, Cometi L, Lopalco G, Dipietrangelo G, Cozzi G, Padoan R, Bixio R, Parisi S, Ditto MC, Lepri G, Fabiani C, Cantarini L, Iannone F, Ramonda R, Frediani B, Guiducci S. Gentileschi S, et al. Ther Adv Musculoskelet Dis. 2026 Apr 26;18:1759720X261442376. doi: 10.1177/1759720X261442376. eCollection 2026. Ther Adv Musculoskelet Dis. 2026. PMID: 42080127 Free PMC article.
DRRs were higher in switchers versus de novo initiators (p = 0.038), also controlling for baseline activity and loading protocol (hazard ratio = 0.25 [95% confidence interval: 0.075-0.848], p = 0.026). De novo patients without induction had lower DRRs (p = 0. …
DRRs were higher in switchers versus de novo initiators (p = 0.038), also controlling for baseline activity and loading protocol (haz …
Stability Assessment of Compounded Niaprazine Oral Solutions to Support an Evidence-Based Beyond-Use Date.
Lopalco A, Martínez-Alonso B, Cortellino M, Annese C, Barbarossa A, Mirgaldi C, Sanrocco A, Antonacci S, Fontana S, Lopedota AA, Denora N. Lopalco A, et al. Pharmaceutics. 2026 Aug 14;18(8):1006. doi: 10.3390/pharmaceutics18081006. Pharmaceutics. 2026. PMID: 42654123 Free PMC article.
Results: Niaprazine concentrations in the syrup remained within pharmacopeial acceptance limits ( 10%) at all temperatures, although a decrease was observed under accelerated conditions (40 C). pH remained stable ( 0.5-unit variation) and the formulation stayed clear and homogen …
Results: Niaprazine concentrations in the syrup remained within pharmacopeial acceptance limits ( 10%) at all temperatures, although a decre …
Transferrin Functionalized Liposomes Loading Dopamine HCl: Development and Permeability Studies across an In Vitro Model of Human Blood-Brain Barrier.
Lopalco A, Cutrignelli A, Denora N, Lopedota A, Franco M, Laquintana V. Lopalco A, et al. Nanomaterials (Basel). 2018 Mar 20;8(3):178. doi: 10.3390/nano8030178. Nanomaterials (Basel). 2018. PMID: 29558440 Free PMC article.
Their stability and drug release kinetics were also evaluated. The apparent permeability (P(e)) values of encapsulated dopamine in functionalized and unfunctionalized liposomes showed that transferrin functionalized nanocarriers could represent appealing non-toxic candidat …
Their stability and drug release kinetics were also evaluated. The apparent permeability (P(e)) values of encapsulated dopamine in fu …