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1994 3
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1999 5
2000 2
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2005 7
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2007 6
2008 5
2009 6
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170 results

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Page 1
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, Feig C, Kultti A, Egeblad M, Fearon DT, Crawford JM, Clevers H, Park Y, Tuveson DA. Öhlund D, et al. J Exp Med. 2017 Mar 6;214(3):579-596. doi: 10.1084/jem.20162024. Epub 2017 Feb 23. J Exp Med. 2017. PMID: 28232471 Free PMC article.
Anti-Interleukin-31 Receptor A Antibody for Atopic Dermatitis.
Ruzicka T, Hanifin JM, Furue M, Pulka G, Mlynarczyk I, Wollenberg A, Galus R, Etoh T, Mihara R, Yoshida H, Stewart J, Kabashima K; XCIMA Study Group. Ruzicka T, et al. N Engl J Med. 2017 Mar 2;376(9):826-835. doi: 10.1056/NEJMoa1606490. N Engl J Med. 2017. PMID: 28249150 Free article. Clinical Trial.
At week 12, among the patients who received nemolizumab every 4 weeks, changes on the pruritus visual-analogue scale were -43.7% in the 0.1-mg group, -59.8% in the 0.5-mg group, and -63.1% in the 2.0-mg group, versus -20.9% in the placebo group (P<0.01 for all compariso …
At week 12, among the patients who received nemolizumab every 4 weeks, changes on the pruritus visual-analogue scale were -43.7% in the 0.1- …
Trends and Disparities in Cardiometabolic Health Among U.S. Adults, 1999-2018.
O'Hearn M, Lauren BN, Wong JB, Kim DD, Mozaffarian D. O'Hearn M, et al. J Am Coll Cardiol. 2022 Jul 12;80(2):138-151. doi: 10.1016/j.jacc.2022.04.046. J Am Coll Cardiol. 2022. PMID: 35798448 Free PMC article.
RESULTS: In 2017-2018, only 6.8% (95% CI: 5.4%-8.1%) of U.S. adults had optimal cardiometabolic health, declining from 1999-2000 (P trend = 0.02). Among components of cardiometabolic health, the largest declines were for adiposity (optimal levels: 33.8%-24.0%; poor levels: …
RESULTS: In 2017-2018, only 6.8% (95% CI: 5.4%-8.1%) of U.S. adults had optimal cardiometabolic health, declining from 1999-2000 (P t …
Mindfulness for pain, depression, anxiety, and quality of life in people with spinal cord injury: a systematic review.
Hearn JH, Cross A. Hearn JH, et al. BMC Neurol. 2020 Jan 21;20(1):32. doi: 10.1186/s12883-020-1619-5. BMC Neurol. 2020. PMID: 31964353 Free PMC article.
Two assessors appraised the studies and demonstrated good agreement (Cohen's k = .848, p < .001). RESULTS: Five papers met the inclusion criteria, and demonstrated a range of results of interventions delivered individually, in a group format, in person, and online. ...

Two assessors appraised the studies and demonstrated good agreement (Cohen's k = .848, p < .001). RESULTS: Five papers met the inc

Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial.
Flohr C, Rosala-Hallas A, Jones AP, Beattie P, Baron S, Browne F, Brown SJ, Gach JE, Greenblatt D, Hearn R, Hilger E, Esdaile B, Cork MJ, Howard E, Lovgren ML, August S, Ashoor F, Williamson PR, McPherson T, O'Kane D, Ravenscroft J, Shaw L, Sinha MD, Spowart C, Taams LS, Thomas BR, Wan M, Sach TH, Irvine AD; TREAT Trial Investigators. Flohr C, et al. Br J Dermatol. 2023 Nov 16;189(6):674-684. doi: 10.1093/bjd/ljad281. Br J Dermatol. 2023. PMID: 37722926 Free article. Clinical Trial.
CyA showed greater improvement in disease severity by 12 weeks [mean difference in o-SCORAD -5.69, 97.5% confidence interval (CI) -10.81 to -0.57 (P = 0.01)]. More participants achieved 50% improvement in o-SCORAD (o-SCORAD 50) at 12 weeks in the CyA arm vs. the MTX arm [o …
CyA showed greater improvement in disease severity by 12 weeks [mean difference in o-SCORAD -5.69, 97.5% confidence interval (CI) -10.81 to …
Incident type 2 diabetes attributable to suboptimal diet in 184 countries.
O'Hearn M, Lara-Castor L, Cudhea F, Miller V, Reedy J, Shi P, Zhang J, Wong JB, Economos CD, Micha R, Mozaffarian D; Global Dietary Database. O'Hearn M, et al. Nat Med. 2023 Apr;29(4):982-995. doi: 10.1038/s41591-023-02278-8. Epub 2023 Apr 17. Nat Med. 2023. PMID: 37069363 Free PMC article.
Stereotactic Body Radiation Therapy for Localized Prostate Cancer: A Systematic Review and Meta-Analysis of Over 6,000 Patients Treated On Prospective Studies.
Jackson WC, Silva J, Hartman HE, Dess RT, Kishan AU, Beeler WH, Gharzai LA, Jaworski EM, Mehra R, Hearn JWD, Morgan TM, Salami SS, Cooperberg MR, Mahal BA, Soni PD, Kaffenberger S, Nguyen PL, Desai N, Feng FY, Zumsteg ZS, Spratt DE. Jackson WC, et al. Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):778-789. doi: 10.1016/j.ijrobp.2019.03.051. Epub 2019 Apr 6. Int J Radiat Oncol Biol Phys. 2019. PMID: 30959121 Free PMC article.
Increasing dose of SBRT was associated with improved biochemical control (P = .018) but worse late grade 3 GU toxicity (P = .014). CONCLUSIONS: Prostate SBRT has substantial prospective evidence supporting its use, with favorable tumor control, patient-reported qual …
Increasing dose of SBRT was associated with improved biochemical control (P = .018) but worse late grade 3 GU toxicity (P = .0 …
A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema.
Fishman A, Martinez F, Naunheim K, Piantadosi S, Wise R, Ries A, Weinmann G, Wood DE; National Emphysema Treatment Trial Research Group. Fishman A, et al. N Engl J Med. 2003 May 22;348(21):2059-73. doi: 10.1056/NEJMoa030287. Epub 2003 May 20. N Engl J Med. 2003. PMID: 12759479 Free article. Clinical Trial.
RESULTS: Overall mortality was 0.11 death per person-year in both treatment groups (risk ratio for death in the surgery group, 1.01; P=0.90). After 24 months, exercise capacity had improved by more than 10 W in 15 percent of the patients in the surgery group, as compared w …
RESULTS: Overall mortality was 0.11 death per person-year in both treatment groups (risk ratio for death in the surgery group, 1.01; P
Presentation abstracts.
Rice L, Sung J, Keane K, Peterson E, Sosnoff J, Farkas G, Swartz A, Strath S, Gorgey A, Berg A, Gater D, Dyson-Hudson T, Malanga G, Cherian C, Michalec M, Kirshblum S, Miller C, Garlanger K, Kortes S, Schnorenberg A, Slavens B, Lee K, Potter-Baker K, Frost F, Plow E, Solinsky R, Wilson C, Henry CA, Lombard A, Maher M, Weir J, Saeed S, Cirnigliaro C, Specht A, Garbarini E, Augustine J, Forrest G, Bauman W, Wecht J, Maher M, Weir J, Lombard A, Saeed S, Kirshblum S, Bauman W, Wecht J, Hearn J, Razvi IS, Wilson C, Henry CA, Sikka S, Callender L, Bennett M, Robertson K, Driver S, Kline-Quiroz C, Donovan J, Botticello A, Arnold D, Latham N, Houlihan B, Bickmore T, Trinh H, Shamekhi A, Ellis T, LaVela SL, Burkhart E, Kale I, Bombardier C, Snoxell E, Knezevic S, Hong E, Asselin P, Cirnigliaro C, Kornfeld S, Gorman P, Forrest G, Bauman W, Spungen A, Farkas G, Berg A, Castillo C, Gater D, Cleveland C, Gabet J, Harrington A, Arenth P, Farkas G, Gorgey A, Dolbow D, Berg A, Gater D, Luther S, Finch D, Bouayad L, Cirnigliaro C, Donovan J, Forrest G, Gater D, Kopp M, Watzlawick R, Martus P, Failli V, Finkenstaedt F, Chen Y, DeVivo M, Dirnagl U, Schwab J MD, LiMonta J, Saeed S, Santiago T, Maher … See abstract for full author list ➔ Rice L, et al. J Spinal Cord Med. 2018 Sep;41(5):599-622. doi: 10.1080/10790268.2018.1498262. J Spinal Cord Med. 2018. PMID: 30132748 Free PMC article. No abstract available.
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
170 results