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49 results

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Page 1
The importance of sleep regularity: a consensus statement of the National Sleep Foundation sleep timing and variability panel.
Sletten TL, Weaver MD, Foster RG, Gozal D, Klerman EB, Rajaratnam SMW, Roenneberg T, Takahashi JS, Turek FW, Vitiello MV, Young MW, Czeisler CA. Sletten TL, et al. Sleep Health. 2023 Dec;9(6):801-820. doi: 10.1016/j.sleh.2023.07.016. Epub 2023 Sep 7. Sleep Health. 2023. PMID: 37684151
Panelists achieved consensus on each question: (1) is daily regularity in sleep timing important for (a) health or (b) performance? and (2) when sleep is of insufficient duration during the week (or work days), is catch-up sleep on weekends (or non-work days) important for …
Panelists achieved consensus on each question: (1) is daily regularity in sleep timing important for (a) health or (b) performance? a …
Neutralizing IFNgamma improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies.
Manni S, Del Bufalo F, Merli P, Silvestris DA, Guercio M, Caruso S, Reddel S, Iaffaldano L, Pezzella M, Di Cecca S, Sinibaldi M, Ottaviani A, Quadraccia MC, Aurigemma M, Sarcinelli A, Ciccone R, Abbaszadeh Z, Ceccarelli M, De Vito R, Lodi MC, Cefalo MG, Mastronuzzi A, De Angelis B, Locatelli F, Quintarelli C. Manni S, et al. Nat Commun. 2023 Jun 9;14(1):3423. doi: 10.1038/s41467-023-38723-y. Nat Commun. 2023. PMID: 37296093 Free PMC article.
Chimeric antigen receptor T (CAR-T) cell therapy may achieve long-lasting remission in patients with B-cell malignancies not responding to conventional therapies. However, potentially severe and hard-to-manage side effects, including cytokine release syndrome (CRS), neurot …
Chimeric antigen receptor T (CAR-T) cell therapy may achieve long-lasting remission in patients with B-cell malignancies not respondi …
Comparison of ezetimibe and atorvastatin versus atorvastatin alone on short-term major adverse cardiac events after percutaneous coronary intervention, a double-blind placebo-controlled randomized clinical trial.
Farshidi H, Bijani B, Sobhani SA, Dastsouz F, Abbaszadeh S. Farshidi H, et al. Trials. 2025 Mar 28;26(1):108. doi: 10.1186/s13063-025-08817-7. Trials. 2025. PMID: 40148971 Free PMC article. Clinical Trial.
Patients were randomly divided into two groups either to receive ezetimibe and atorvastatin (group A) or atorvastatin alone (group B). Patients were followed for 1 month for major cardiovascular events and drug side effects. ...Three (2.7%) patients in group A and 1 patien …
Patients were randomly divided into two groups either to receive ezetimibe and atorvastatin (group A) or atorvastatin alone (group B) …
IL-10-producing B cells play important role in the pathogenesis of recurrent pregnancy loss.
Danaii S, Ghorbani F, Ahmadi M, Abbaszadeh H, Koushaeian L, Soltani-Zangbar MS, Mehdizadeh A, Hojjat-Farsangi M, Kafil HS, Aghebati-Maleki L, Yousefi M. Danaii S, et al. Int Immunopharmacol. 2020 Oct;87:106806. doi: 10.1016/j.intimp.2020.106806. Epub 2020 Jul 18. Int Immunopharmacol. 2020. PMID: 32693358
Then, the frequency of IL-10(+) CD19(+) B cells was found out using flow cytometry. Enzyme-linked immunosorbent assay (ELISA) was used to assess the levels of IL-10 in supernatant medium and serum of stimulated B cells, as well as those of several serum autoantibodi …
Then, the frequency of IL-10(+) CD19(+) B cells was found out using flow cytometry. Enzyme-linked immunosorbent assay (ELISA) was use …
Strategy to prevent epitope masking in CAR.CD19+ B-cell leukemia blasts.
Quintarelli C, Guercio M, Manni S, Boffa I, Sinibaldi M, Di Cecca S, Caruso S, Abbaszadeh Z, Camera A, Cembrola B, Ciccone R, Orfao A, Martin-Martin L, Gutierrez-Herrero S, Herrero-Garcia M, Cazzaniga G, Nunes V, Songia S, Marcatili P, Marin FI, Ruella M, Bertaina V, Vinti L, Del Bufalo F, Algeri M, Merli P, De Angelis B, Locatelli F. Quintarelli C, et al. J Immunother Cancer. 2021 Jun;9(6):e001514. doi: 10.1136/jitc-2020-001514. J Immunother Cancer. 2021. PMID: 34135100 Free PMC article.
Chimeric antigen receptor T-cells (CAR T-cells) for the treatment of relapsing/refractory B-cell precursor acute lymphoblastic leukemia have led to exciting clinical results. ...DPs were deeply characterized by flow cytometry and molecular biology for Ig-rearrangements, sh …
Chimeric antigen receptor T-cells (CAR T-cells) for the treatment of relapsing/refractory B-cell precursor acute lymphoblastic leukem …
The effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on the cognitive and motor functions in rodents: A systematic review and meta-analysis.
Narmashiri A, Abbaszadeh M, Ghazizadeh A. Narmashiri A, et al. Neurosci Biobehav Rev. 2022 Sep;140:104792. doi: 10.1016/j.neubiorev.2022.104792. Epub 2022 Jul 22. Neurosci Biobehav Rev. 2022. PMID: 35872230
Memory and motor deficits are commonly identified in Parkinson's disease (PD). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is transformed to MPP+ via monoamine oxidase B (MAOB), which causes oxidative stress and destroys dopaminergic (DA) neurons in substantia nigr …
Memory and motor deficits are commonly identified in Parkinson's disease (PD). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is transf …
Antioxidant and anticancer potentials of edible flowers: where do we stand?
Fakhri S, Tomas M, Capanoglu E, Hussain Y, Abbaszadeh F, Lu B, Hu X, Wu J, Zou L, Smeriglio A, Simal-Gandara J, Cao H, Xiao J, Khan H. Fakhri S, et al. Crit Rev Food Sci Nutr. 2022;62(31):8589-8645. doi: 10.1080/10408398.2021.1931022. Epub 2021 Jun 7. Crit Rev Food Sci Nutr. 2022. PMID: 34096420 Review.
As the interconnected pathways to oxidative stress, inflammatory mediators, including tumor necrosis factor (TNF)-alpha, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB), interleukins (ILs) as well as apoptotic pathways such as Bcl-2-associated X …
As the interconnected pathways to oxidative stress, inflammatory mediators, including tumor necrosis factor (TNF)-alpha, nuclear factor kapp …
Inclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies.
Guercio M, Manni S, Boffa I, Caruso S, Di Cecca S, Sinibaldi M, Abbaszadeh Z, Camera A, Ciccone R, Polito VA, Ferrandino F, Reddel S, Catanoso ML, Bocceri E, Del Bufalo F, Algeri M, De Angelis B, Quintarelli C, Locatelli F. Guercio M, et al. Front Immunol. 2021 Oct 19;12:755639. doi: 10.3389/fimmu.2021.755639. eCollection 2021. Front Immunol. 2021. PMID: 34737753 Free PMC article.
T cells engineered with chimeric antigen receptor (CAR-T cells) are an effective treatment in patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia or B-cell non-Hodgkin lymphoma. Despite the reported exciting clinical results, the CAR-T ce …
T cells engineered with chimeric antigen receptor (CAR-T cells) are an effective treatment in patients with relapsed/refractory B-cel …
Effects of dimethyl itaconate on expressions of NGFI-A and NGFI-B and inflammatory cytokines in the spinal cord in the formalin test.
Rahimi K, Abbaszadeh M, Bakhtazad S, Ghotbeddin Z. Rahimi K, et al. Brain Commun. 2024 Nov 11;6(6):fcae397. doi: 10.1093/braincomms/fcae397. eCollection 2024. Brain Commun. 2024. PMID: 39568551 Free PMC article.
We evaluated the impact of DMI on the spinal cords NGFI-A and NGFI-B expressions and inflammatory and anti-inflammatory cytokines [interleukin-1 beta (IL-1beta), tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) and interleukin-10 (IL-10)]. ...Through our rese …
We evaluated the impact of DMI on the spinal cords NGFI-A and NGFI-B expressions and inflammatory and anti-inflammatory cytokines [in …
49 results