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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 1
2000 1
2001 1
2004 6
2005 67
2006 91
2007 102
2008 135
2009 119
2010 144
2011 142
2012 173
2013 232
2014 328
2015 357
2016 437
2017 401
2018 472
2019 473
2020 563
2021 584
2022 587
2023 581
2024 5

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5,237 results

Results by year

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Page 1
High performance plasma amyloid-β biomarkers for Alzheimer's disease.
Nakamura A, Kaneko N, Villemagne VL, Kato T, Doecke J, Doré V, Fowler C, Li QX, Martins R, Rowe C, Tomita T, Matsuzaki K, Ishii K, Ishii K, Arahata Y, Iwamoto S, Ito K, Tanaka K, Masters CL, Yanagisawa K. Nakamura A, et al. Nature. 2018 Feb 8;554(7691):249-254. doi: 10.1038/nature25456. Epub 2018 Jan 31. Nature. 2018. PMID: 29420472
To facilitate clinical trials of disease-modifying therapies for Alzheimer's disease, which are expected to be most efficacious at the earliest and mildest stages of the disease, supportive biomarker information is necessary. ...Both data sets i …
To facilitate clinical trials of disease-modifying therapies for Alzheimer's disease, which are expected to be m …
Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly.
McNeil JJ, Wolfe R, Woods RL, Tonkin AM, Donnan GA, Nelson MR, Reid CM, Lockery JE, Kirpach B, Storey E, Shah RC, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Johnston CI, Ryan J, Radziszewska B, Jelinek M, Malik M, Eaton CB, Brauer D, Cloud G, Wood EM, Mahady SE, Satterfield S, Grimm R, Murray AM; ASPREE Investigator Group. McNeil JJ, et al. N Engl J Med. 2018 Oct 18;379(16):1509-1518. doi: 10.1056/NEJMoa1805819. Epub 2018 Sep 16. N Engl J Med. 2018. PMID: 30221597 Free PMC article. Clinical Trial.
METHODS: From 2010 through 2014, we enrolled community-dwelling men and women in Australia and the United States who were 70 years of age or older (or 65 years of age among blacks and Hispanics in the United States) and did not have cardiovascular disease, dementia, …
METHODS: From 2010 through 2014, we enrolled community-dwelling men and women in Australia and the United States who were 70 years of …
A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation.
Grubman A, Chew G, Ouyang JF, Sun G, Choo XY, McLean C, Simmons RK, Buckberry S, Vargas-Landin DB, Poppe D, Pflueger J, Lister R, Rackham OJL, Petretto E, Polo JM. Grubman A, et al. Nat Neurosci. 2019 Dec;22(12):2087-2097. doi: 10.1038/s41593-019-0539-4. Nat Neurosci. 2019. PMID: 31768052
We detail cell-type-specific gene expression patterns, unveiling how transcriptional changes in specific cell subpopulations are associated with Alzheimer's disease. We report that the Alzheimer's disease risk gene APOE is specifically re …
We detail cell-type-specific gene expression patterns, unveiling how transcriptional changes in specific cell subpopulations are associated …
Deep Intronic FGF14 GAA Repeat Expansion in Late-Onset Cerebellar Ataxia.
Pellerin D, Danzi MC, Wilke C, Renaud M, Fazal S, Dicaire MJ, Scriba CK, Ashton C, Yanick C, Beijer D, Rebelo A, Rocca C, Jaunmuktane Z, Sonnen JA, Larivière R, Genís D, Molina Porcel L, Choquet K, Sakalla R, Provost S, Robertson R, Allard-Chamard X, Tétreault M, Reiling SJ, Nagy S, Nishadham V, Purushottam M, Vengalil S, Bardhan M, Nalini A, Chen Z, Mathieu J, Massie R, Chalk CH, Lafontaine AL, Evoy F, Rioux MF, Ragoussis J, Boycott KM, Dubé MP, Duquette A, Houlden H, Ravenscroft G, Laing NG, Lamont PJ, Saporta MA, Schüle R, Schöls L, La Piana R, Synofzik M, Zuchner S, Brais B. Pellerin D, et al. N Engl J Med. 2023 Jan 12;388(2):128-141. doi: 10.1056/NEJMoa2207406. Epub 2022 Dec 14. N Engl J Med. 2023. PMID: 36516086 Free PMC article.
We then tested for association between the repeat expansion and disease in two independent case-control series - one French Canadian (66 patients and 209 controls) and the other German (228 patients and 199 controls). ...RESULTS: In the six French Canadian patients, we ide …
We then tested for association between the repeat expansion and disease in two independent case-control series - one French Canadian …
MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study.
Hosking DE, Eramudugolla R, Cherbuin N, Anstey KJ. Hosking DE, et al. Alzheimers Dement. 2019 Apr;15(4):581-589. doi: 10.1016/j.jalz.2018.12.011. Epub 2019 Feb 28. Alzheimers Dement. 2019. PMID: 30826160 Review.
METHODS: We investigated MIND and Mediterranean diet relations with 12-year incidence of Alzheimer's disease/Vascular dementia (National Institute of Neurological Disorders criteria) and mild cognitive impairment (Winbald criteria) in the Personality and Tota …
METHODS: We investigated MIND and Mediterranean diet relations with 12-year incidence of Alzheimer's disease/Vascular d …
Dementia.
Taylor ME, Close JCT. Taylor ME, et al. Handb Clin Neurol. 2018;159:303-321. doi: 10.1016/B978-0-444-63916-5.00019-7. Handb Clin Neurol. 2018. PMID: 30482323 Review.
Dementia is a syndrome seen most commonly in older people and characterized by a decline in cognitive performance which impacts on the person's ability to function. There are approximately 47 million people worldwide with dementia and there are 10 million new cases every y …
Dementia is a syndrome seen most commonly in older people and characterized by a decline in cognitive performance which impacts on the perso …
Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's disease.
Chatterjee P, Pedrini S, Ashton NJ, Tegg M, Goozee K, Singh AK, Karikari TK, Simrén J, Vanmechelen E, Armstrong NJ, Hone E, Asih PR, Taddei K, Doré V, Villemagne VL, Sohrabi HR, Zetterberg H, Masters CL, Blennow K, Martins RN. Chatterjee P, et al. Alzheimers Dement. 2022 Jun;18(6):1141-1154. doi: 10.1002/alz.12447. Epub 2021 Sep 8. Alzheimers Dement. 2022. PMID: 34494715
INTRODUCTION: This study involved a parallel comparison of the diagnostic and longitudinal monitoring potential of plasma glial fibrillary acidic protein (GFAP), total tau (t-tau), phosphorylated tau (p-tau181 and p-tau231), and neurofilament light (NFL) in preclinical Alzheim …
INTRODUCTION: This study involved a parallel comparison of the diagnostic and longitudinal monitoring potential of plasma glial fibrillary a …
Development and validation of an interpretable deep learning framework for Alzheimer's disease classification.
Qiu S, Joshi PS, Miller MI, Xue C, Zhou X, Karjadi C, Chang GH, Joshi AS, Dwyer B, Zhu S, Kaku M, Zhou Y, Alderazi YJ, Swaminathan A, Kedar S, Saint-Hilaire MH, Auerbach SH, Yuan J, Sartor EA, Au R, Kolachalama VB. Qiu S, et al. Brain. 2020 Jun 1;143(6):1920-1933. doi: 10.1093/brain/awaa137. Brain. 2020. PMID: 32357201 Free PMC article.
Alzheimer's disease is the primary cause of dementia worldwide, with an increasing morbidity burden that may outstrip diagnosis and management capacity as the population ages. ...The model was trained using clinically diagnosed Alzheimer's di …
Alzheimer's disease is the primary cause of dementia worldwide, with an increasing morbidity burden that may outstrip d …
Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services-part 2 of 6.
Ranson JM, Rittman T, Hayat S, Brayne C, Jessen F, Blennow K, van Duijn C, Barkhof F, Tang E, Mummery CJ, Stephan BCM, Altomare D, Frisoni GB, Ribaldi F, Molinuevo JL, Scheltens P, Llewellyn DJ; European Task Force for Brain Health Services. Ranson JM, et al. Alzheimers Res Ther. 2021 Oct 11;13(1):169. doi: 10.1186/s13195-021-00895-4. Alzheimers Res Ther. 2021. PMID: 34635138 Free PMC article. Review.
These services will complement existing memory clinics by targeting cognitively unimpaired individuals, where the focus is on risk profiling and personalized risk reduction interventions rather than diagnosing and treating late-stage disease. In this article, we review key …
These services will complement existing memory clinics by targeting cognitively unimpaired individuals, where the focus is on risk profiling …
Effect of Aspirin on All-Cause Mortality in the Healthy Elderly.
McNeil JJ, Nelson MR, Woods RL, Lockery JE, Wolfe R, Reid CM, Kirpach B, Shah RC, Ives DG, Storey E, Ryan J, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Radziszewska B, Grimm R, Murray AM; ASPREE Investigator Group. McNeil JJ, et al. N Engl J Med. 2018 Oct 18;379(16):1519-1528. doi: 10.1056/NEJMoa1803955. Epub 2018 Sep 16. N Engl J Med. 2018. PMID: 30221595 Free PMC article. Clinical Trial.
METHODS: From 2010 through 2014, we enrolled community-dwelling persons in Australia and the United States who were 70 years of age or older (or 65 years of age among blacks and Hispanics in the United States) and did not have cardiovascular disease, dementia, or di …
METHODS: From 2010 through 2014, we enrolled community-dwelling persons in Australia and the United States who were 70 years of age o …
5,237 results