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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 1
1966 1
1967 1
1968 4
1969 19
1970 24
1971 23
1972 31
1973 16
1974 31
1975 30
1976 25
1977 28
1978 29
1979 26
1980 33
1981 29
1982 45
1983 40
1984 40
1985 32
1986 39
1987 19
1988 35
1989 29
1990 28
1991 22
1992 29
1993 22
1994 25
1995 28
1996 29
1997 31
1998 23
1999 23
2000 30
2001 26
2002 30
2003 28
2004 34
2005 20
2006 24
2007 35
2008 26
2009 23
2010 27
2011 34
2012 30
2013 28
2014 24
2015 37
2016 28
2017 43
2018 35
2019 34
2020 40
2021 29
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1,493 results
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Page 1
Doxepin.
[No authors listed] [No authors listed] 2018 Jan 8. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2018 Jan 8. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643366 Free Books & Documents. Review.
Doxepin is a tricyclic antidepressant that widely used in the therapy of depression. Doxepin can cause mild and transient serum enzyme elevations but is a rare cause of clinically apparent acute cholestatic liver injury....
Doxepin is a tricyclic antidepressant that widely used in the therapy of depression. Doxepin can cause mild and transient seru
Doxepin.
[No authors listed] [No authors listed] 2021 Feb 15. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. 2021 Feb 15. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. PMID: 30000240 Free Books & Documents. Review.
Because of its sedating potential, active metabolite, presence in infant serum, two reports of adverse effects in breastfed infants, and only one report of use without apparent adverse reactions, doxepin is a poor choice and other agents are preferred, especially while nur …
Because of its sedating potential, active metabolite, presence in infant serum, two reports of adverse effects in breastfed infants, and onl …
Doxepin.
Almasi A, Meza CE. Almasi A, et al. 2021 Jul 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–. 2021 Jul 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–. PMID: 31194446 Free Books & Documents. Review.
Doxepin is a medication used in the treatment of major depressive disorder, anxiety, insomnia, as well as in the management of skin pruritus. ...This activity describes the indications, dosing, side effects, and contraindications for doxepin as a valuable agent in t
Doxepin is a medication used in the treatment of major depressive disorder, anxiety, insomnia, as well as in the management of skin p
A Review of Suvorexant, Doxepin, Ramelteon, and Tasimelteon for the Treatment of Insomnia in Geriatric Patients.
Edmonds C, Swanoski M. Edmonds C, et al. Consult Pharm. 2017 Mar 1;32(3):156-160. doi: 10.4140/TCP.n.2017.156. Consult Pharm. 2017. PMID: 28270270 Review.
Therapeutic alternatives approved by the Food and Drug Administration include suvorexant, doxepin, ramelteon, and tasimelteon, which have shown efficacy and safety in various studies. ...
Therapeutic alternatives approved by the Food and Drug Administration include suvorexant, doxepin, ramelteon, and tasimelteon, which …
Insomnia: Pharmacologic Therapy.
Matheson E, Hainer BL. Matheson E, et al. Am Fam Physician. 2017 Jul 1;96(1):29-35. Am Fam Physician. 2017. PMID: 28671376 Free article. Review.
Understanding the risks and benefits of insomnia medications is critical. Controlled-release melatonin and doxepin are recommended as first-line agents in older adults; the so-called z-drugs (zolpidem, eszopiclone, and zaleplon) should be reserved for use if the first-line …
Understanding the risks and benefits of insomnia medications is critical. Controlled-release melatonin and doxepin are recommended as …
Repurposing Doxepin to Ameliorate Steatosis and Hyperglycemia by Activating FAM3A Signaling Pathway.
Chen Z, Liu X, Luo Y, Wang J, Meng Y, Sun L, Chang Y, Cui Q, Yang J. Chen Z, et al. Diabetes. 2020 Jun;69(6):1126-1139. doi: 10.2337/db19-1038. Epub 2020 Apr 20. Diabetes. 2020. PMID: 32312868 Free PMC article.
Drug-repurposing methodology predicted that antidepressive drug doxepin was among the drugs that potentially activated FAM3A expression. ...Notably, doxepin failed to correct dysregulated glucose and lipid metabolism in FAM3A-deficient mice fed on high-fat diet. ...
Drug-repurposing methodology predicted that antidepressive drug doxepin was among the drugs that potentially activated FAM3A expressi …
Optimizing doxepin therapy in dermatology: introducing blood level monitoring and genotype testing.
Myers B, Reddy V, Chan S, Thibodeaux Q, Brownstone N, Koo J. Myers B, et al. J Dermatolog Treat. 2020 May 6:1-7. doi: 10.1080/09546634.2020.1762841. Online ahead of print. J Dermatolog Treat. 2020. PMID: 32347140
Doxepin, a tricyclic antidepressant, is the most efficacious antipruritic available to dermatologists; however its use is often suboptimal because of significant interindividual variability in doxepin plasma levels and clinical response between patients taking the s
Doxepin, a tricyclic antidepressant, is the most efficacious antipruritic available to dermatologists; however its use is often subop
Doxepin for insomnia: a systematic review of randomized placebo-controlled trials.
Yeung WF, Chung KF, Yung KP, Ng TH. Yeung WF, et al. Sleep Med Rev. 2015 Feb;19:75-83. doi: 10.1016/j.smrv.2014.06.001. Epub 2014 Jun 19. Sleep Med Rev. 2015. PMID: 25047681 Review.
A total of nine randomized placebo-controlled trials were analyzed. Six studies were on doxepin 1-6 mg/d, two on doxepin 25-300 mg/d, and one on ramelteon 8 mg and doxepin 3 mg combined. ...We concluded that low-dose doxepin for 1-2 nights appeared to …
A total of nine randomized placebo-controlled trials were analyzed. Six studies were on doxepin 1-6 mg/d, two on doxepin 25-30 …
Doxepin in children and adolescents with symptoms of insomnia: a single-center experience.
Shah YD, Stringel V, Pavkovic I, Kothare SV. Shah YD, et al. J Clin Sleep Med. 2020 May 15;16(5):743-747. doi: 10.5664/jcsm.8338. Epub 2020 Feb 7. J Clin Sleep Med. 2020. PMID: 32029069 Free PMC article.
The objective of this study was to evaluate the efficacy and tolerability of doxepin in pediatric patients. METHODS: This is a retrospective single-center chart review of children and adolescents (2-17 years of age) whose sleep failed to improve with behavioral interventio …
The objective of this study was to evaluate the efficacy and tolerability of doxepin in pediatric patients. METHODS: This is a retros …
Low-dose doxepin: in the treatment of insomnia.
Weber J, Siddiqui MA, Wagstaff AJ, McCormack PL. Weber J, et al. CNS Drugs. 2010 Aug;24(8):713-20. doi: 10.2165/11200810-000000000-00000. CNS Drugs. 2010. PMID: 20658801 Review.
Symptom control was maintained for up to 12 weeks of low-dose doxepin administration and there was no evidence of physical dependence or worsening insomnia after doxepin withdrawal. ...Oral, low-dose doxepin was generally well tolerated in clinical trials....
Symptom control was maintained for up to 12 weeks of low-dose doxepin administration and there was no evidence of physical dependence …
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