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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 2
1971 3
1972 1
1973 13
1974 7
1975 14
1976 24
1977 16
1978 9
1979 26
1980 33
1981 31
1982 38
1983 50
1984 69
1985 54
1986 86
1987 52
1988 56
1989 54
1990 46
1991 30
1992 49
1993 45
1994 54
1995 45
1996 37
1997 40
1998 34
1999 45
2000 45
2001 46
2002 39
2003 35
2004 50
2005 47
2006 49
2007 64
2008 41
2009 48
2010 41
2011 55
2012 47
2013 46
2014 51
2015 66
2016 57
2017 69
2018 90
2019 75
2020 83
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2,107 results
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Page 1
Rediscovering trazodone for the treatment of major depressive disorder.
Fagiolini A, Comandini A, Catena Dell'Osso M, Kasper S. Fagiolini A, et al. CNS Drugs. 2012 Dec;26(12):1033-49. doi: 10.1007/s40263-012-0010-5. CNS Drugs. 2012. PMID: 23192413 Free PMC article. Review.
Trazodone is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). ...Recent focus has been placed on the development of a new prolonged-release once-a-day formulation of trazodone (TzCOAD), which
Trazodone is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs
Off-Label Trazodone Prescription: Evidence, Benefits and Risks.
Bossini L, Coluccia A, Casolaro I, Benbow J, Amodeo G, De Giorgi R, Fagiolini A. Bossini L, et al. Curr Pharm Des. 2015;21(23):3343-51. doi: 10.2174/1381612821666150619092236. Curr Pharm Des. 2015. PMID: 26088119 Review.
Other, not officially approved, uses of trazodone include: the treatment of bulimia, benzodiazepine and/or alcohol dependence or abuse, fibromyalgia, degenerative diseases of the central nervous system such as dementia and other organic disorders, schizophrenia, chronic pa …
Other, not officially approved, uses of trazodone include: the treatment of bulimia, benzodiazepine and/or alcohol dependence or abus …
A review of trazodone use in psychiatric and medical conditions.
Khouzam HR. Khouzam HR. Postgrad Med. 2017 Jan;129(1):140-148. doi: 10.1080/00325481.2017.1249265. Epub 2016 Oct 28. Postgrad Med. 2017. PMID: 27744763 Review.
Trazodone is an antidepressant that is FDA-approved for the treatment of depression. ...Despite trazodone's favorable effects in the treatment of FDA-unapproved psychiatric and medical conditions, large, randomized controlled clinical trials are still needed to conf
Trazodone is an antidepressant that is FDA-approved for the treatment of depression. ...Despite trazodone's favorable effects
Clinical guidance for the use of trazodone in major depressive disorder and concomitant conditions: pharmacology and clinical practice.
Cuomo A, Ballerini A, Bruni AC, Decina P, Di Sciascio G, Fiorentini A, Scaglione F, Vampini C, Fagiolini A. Cuomo A, et al. Riv Psichiatr. 2019 Jul-Aug;54(4):137-149. doi: 10.1708/3202.31796. Riv Psichiatr. 2019. PMID: 31379379 Review.
AIM: To provide a review of the clinically relevant evidence pertaining to the use of trazodone in major depressive disorder. METHODS: Medline and Cochrane Library searches were searched using the keywords 'trazodone' AND 'depression', to identify the most relevant …
AIM: To provide a review of the clinically relevant evidence pertaining to the use of trazodone in major depressive disorder. METHODS …
Trazodone.
Shin JJ, Saadabadi A. Shin JJ, et al. 2020 May 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–. StatPearls. 2020 Jan–. PMID: 29262060 Free Books & Documents. Review.
Trazodone is an FDA-approved antidepressant for treating major depressive disorders. ...Trazodone has also been used for post-traumatic stress disorder (PTSD) if the first-line treatment use of SSRIs does not show efficacy. ...
Trazodone is an FDA-approved antidepressant for treating major depressive disorders. ...Trazodone has also been used for post-
Effects of oral trazodone on echocardiographic and hemodynamic variables in healthy cats.
Fries RC, Kadotani S, Vitt JP, Schaeffer DJ. Fries RC, et al. J Feline Med Surg. 2019 Dec;21(12):1080-1085. doi: 10.1177/1098612X18814565. Epub 2018 Nov 30. J Feline Med Surg. 2019. PMID: 30499766
Mean echocardiographic and hemodynamic variables were calculated for pre- and post-trazodone examinations for each cat. Pre- and post-trazodone variables were analyzed with a paired t-test with significance set at P <0.05. ...There were no clinically significant …
Mean echocardiographic and hemodynamic variables were calculated for pre- and post-trazodone examinations for each cat. Pre- and post …
Effects of trazodone on behavioral signs of stress in hospitalized dogs.
Gilbert-Gregory SE, Stull JW, Rice MR, Herron ME. Gilbert-Gregory SE, et al. J Am Vet Med Assoc. 2016 Dec 1;249(11):1281-1291. doi: 10.2460/javma.249.11.1281. J Am Vet Med Assoc. 2016. PMID: 27875082 Clinical Trial.
OBJECTIVE To determine the effects of trazodone treatment on behavioral signs of stress in hospitalized dogs. ...Odds of reduced panting and reduced frenetic behaviors at time 2 for trazodone-treated dogs were > 2 times those for environmentally matched dogs. ...
OBJECTIVE To determine the effects of trazodone treatment on behavioral signs of stress in hospitalized dogs. ...Odds of reduced pant …
Pharmacokinetics, pharmacodynamics and clinical use of trazodone and its active metabolite m-chlorophenylpiperazine in the horse.
Davis JL, Schirmer J, Medlin E. Davis JL, et al. J Vet Pharmacol Ther. 2018 Jun;41(3):393-401. doi: 10.1111/jvp.12477. Epub 2018 Jan 14. J Vet Pharmacol Ther. 2018. PMID: 29333613 Free PMC article. Clinical Trial.
The aims of this study were to determine the pharmacokinetics of oral trazodone in experimental horses and to evaluate the effect of oral trazodone in clinical horses. Six experimental horses were administered trazodone at 7.5 or 10 mg/kg. Plasma concentratio …
The aims of this study were to determine the pharmacokinetics of oral trazodone in experimental horses and to evaluate the effect of …
Treatment of Alzheimer's Disease: Trazodone, Sleep, Serotonin, Norepinephrine, and Future Directions.
Ashford JW. Ashford JW. J Alzheimers Dis. 2019;67(3):923-930. doi: 10.3233/JAD-181106. J Alzheimers Dis. 2019. PMID: 30776014 Free PMC article.
For participants considered to have AD pathology, trazodone non-users declined at a rate 2.4 times greater than those taking trazodone for sleep over a 4-year period. ...If trazodone really does provide such a dramatic slowing in the development of dementia a …
For participants considered to have AD pathology, trazodone non-users declined at a rate 2.4 times greater than those taking trazo
Trazodone and Parkinsonism: The Link Strengthens.
Sarwar AI. Sarwar AI. Clin Neuropharmacol. 2018 May/Jun;41(3):106-108. doi: 10.1097/WNF.0000000000000278. Clin Neuropharmacol. 2018. PMID: 29634584
Trazodone, the most sedating atypical antidepressant, is widely used as an off-label hypnotic especially in the elderly. ...A secondary cause was suspected by his movement disorder neurologist that led to rapid withdrawal of trazodone and complete reversal of his sy
Trazodone, the most sedating atypical antidepressant, is widely used as an off-label hypnotic especially in the elderly. ...A seconda
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