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2013 1
2014 12
2015 2
2022 0
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Page 1
Autocatalytic activity and substrate specificity of the pestivirus N-terminal protease Npro.
Gottipati K, Acholi S, Ruggli N, Choi KH. Gottipati K, et al. Virology. 2014 Mar;452-453:303-9. doi: 10.1016/j.virol.2014.01.026. Epub 2014 Feb 19. Virology. 2014. PMID: 24606708 Free article.
Once released, N(pro) blocks the hosts interferon response by inducing degradation of interferon regulatory factor-3. N(pro)s intracellular autocatalytic activity and lack of trans-activity have hampered in vitro cleavage studies to establish its substrate specificity and …
Once released, N(pro) blocks the hosts interferon response by inducing degradation of interferon regulatory factor-3. N(pro)s intrace …
Newly isolated mAbs broaden the neutralizing epitope in murine norovirus.
Kolawole AO, Xia C, Li M, Gamez M, Yu C, Rippinger CM, Yucha RE, Smith TJ, Wobus CE. Kolawole AO, et al. J Gen Virol. 2014 Sep;95(Pt 9):1958-1968. doi: 10.1099/vir.0.066753-0. Epub 2014 Jun 4. J Gen Virol. 2014. PMID: 24899153 Free PMC article.
The non-neutralizing anti-MNV-1 IgG2b antibody 5C4.10 was mapped to the S domain of the MNV-1 capsid, whilst the epitopes of the neutralizing anti-MNV-1 IgA antibodies 2D3.7 and 4F9.4 were mapped to the P domain. ...
The non-neutralizing anti-MNV-1 IgG2b antibody 5C4.10 was mapped to the S domain of the MNV-1 capsid, whilst the epitopes of the neut …
Use of small-angle X-ray scattering to investigate the structure and function of dengue virus NS3 and NS5.
Choi KH, Morais M. Choi KH, et al. Methods Mol Biol. 2014;1138:241-52. doi: 10.1007/978-1-4939-0348-1_15. Methods Mol Biol. 2014. PMID: 24696341 Free PMC article.
Similarly, the molecular weight of macromolecular complexes can be directly determined from the complex's scattering profile, providing insight into the oligomeric state and stoichiometry of the assembly. ...
Similarly, the molecular weight of macromolecular complexes can be directly determined from the complex's scattering profile, providi …
Small-molecule Bax agonists for cancer therapy.
Xin M, Li R, Xie M, Park D, Owonikoko TK, Sica GL, Corsino PE, Zhou J, Ding C, White MA, Magis AT, Ramalingam SS, Curran WJ, Khuri FR, Deng X. Xin M, et al. Nat Commun. 2014 Sep 17;5:4935. doi: 10.1038/ncomms5935. Nat Commun. 2014. PMID: 25230299 Free PMC article.
A high-throughput drop microfluidic system for virus culture and analysis.
Fischer AE, Wu SK, Proescher JB, Rotem A, Chang CB, Zhang H, Tao Y, Mehoke TS, Thielen PM, Kolawole AO, Smith TJ, Wobus CE, Weitz DA, Lin JS, Feldman AB, Wolfe JT. Fischer AE, et al. J Virol Methods. 2015 Mar;213:111-7. doi: 10.1016/j.jviromet.2014.12.003. Epub 2014 Dec 16. J Virol Methods. 2015. PMID: 25522923
The ACTTION-American Pain Society Pain Taxonomy (AAPT): an evidence-based and multidimensional approach to classifying chronic pain conditions.
Fillingim RB, Bruehl S, Dworkin RH, Dworkin SF, Loeser JD, Turk DC, Widerstrom-Noga E, Arnold L, Bennett R, Edwards RR, Freeman R, Gewandter J, Hertz S, Hochberg M, Krane E, Mantyh PW, Markman J, Neogi T, Ohrbach R, Paice JA, Porreca F, Rappaport BA, Smith SM, Smith TJ, Sullivan MD, Verne GN, Wasan AD, Wesselmann U. Fillingim RB, et al. J Pain. 2014 Mar;15(3):241-9. doi: 10.1016/j.jpain.2014.01.004. J Pain. 2014. PMID: 24581634 Free PMC article.
To address these gaps, the Analgesic, Anesthetic, and Addiction Clinical Trial Translations Innovations Opportunities and Networks (ACTTION) public-private partnership with the U.S. Food and Drug Administration and the American Pain Society (APS) have joined together to de …
To address these gaps, the Analgesic, Anesthetic, and Addiction Clinical Trial Translations Innovations Opportunities and Networks (ACTTION) …
Identification of a novel inhibitor of dengue virus protease through use of a virtual screening drug discovery Web portal.
Viswanathan U, Tomlinson SM, Fonner JM, Mock SA, Watowich SJ. Viswanathan U, et al. J Chem Inf Model. 2014 Oct 27;54(10):2816-25. doi: 10.1021/ci500531r. Epub 2014 Oct 10. J Chem Inf Model. 2014. PMID: 25263519
Our drug discovery portal, an extension of virtual screening studies performed using IBM's World Community Grid, facilitated access to supercomputer resources managed by the Texas Advanced Computing Center (TACC) and enabled druglike commercially available small-molecule l …
Our drug discovery portal, an extension of virtual screening studies performed using IBM's World Community Grid, facilitated access t …
12 results