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The following term was not found in PubMed: Moghtased-Azar
Page 1
KH-RNA interactions: back in the groove.
Nicastro G, Taylor IA, Ramos A. Nicastro G, et al. Curr Opin Struct Biol. 2015 Feb;30:63-70. doi: 10.1016/j.sbi.2015.01.002. Epub 2015 Jan 24. Curr Opin Struct Biol. 2015. PMID: 25625331 Review.
The structure of the KH fold is well characterised and some initial rules for KH-RNA recognition have been drafted. ...These advances set the scene for a detailed molecular understanding of KH selection of the cellular targets....
The structure of the KH fold is well characterised and some initial rules for KH-RNA recognition have been drafted. ...These a …
KH-Domain Poly(C)-Binding Proteins as Versatile Regulators of Multiple Biological Processes.
Nazarov IB, Bakhmet EI, Tomilin AN. Nazarov IB, et al. Biochemistry (Mosc). 2019 Mar;84(3):205-219. doi: 10.1134/S0006297919030039. Biochemistry (Mosc). 2019. PMID: 31221059 Review.
Deregulation of KH-domain protein expression is frequently associated with severe developmental defects and neoplasia. This review summarizes progress in studies of the KH-domain proteins made over past two decades. The review also reports our recent finding implyin …
Deregulation of KH-domain protein expression is frequently associated with severe developmental defects and neoplasia. This review su …
Structure-function analysis of DEAD-box helicase DDX43.
Singh RS, Arna AB, Dong H, Yadav M, Aggarwal A, Wu Y. Singh RS, et al. Methods. 2022 Aug;204:286-299. doi: 10.1016/j.ymeth.2022.03.002. Epub 2022 Mar 4. Methods. 2022. PMID: 35257897 Free article.
DDX43 (DEAD-box helicase 43), also known as HAGE (helicase antigen gene), is a member of the DEAD-box protein family. It contains a K homology (KH) domain in its N terminus, a helicase core domain in its C terminus, and a flexible linker domain in between. ...Moreover, the …
DDX43 (DEAD-box helicase 43), also known as HAGE (helicase antigen gene), is a member of the DEAD-box protein family. It contains a K homolo …
Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells.
Takahashi D, Hoshina N, Kabumoto Y, Maeda Y, Suzuki A, Tanabe H, Isobe J, Yamada T, Muroi K, Yanagisawa Y, Nakamura A, Fujimura Y, Saeki A, Ueda M, Matsumoto R, Asaoka H, Clarke JM, Harada Y, Umemoto E, Komatsu N, Okada T, Takayanagi H, Takeda K, Tomura M, Hase K. Takahashi D, et al. EBioMedicine. 2020 Aug;58:102913. doi: 10.1016/j.ebiom.2020.102913. Epub 2020 Jul 22. EBioMedicine. 2020. PMID: 32711255 Free PMC article.
FUNDING: This work was supported by AMED-Crest (16gm1010004h0101, 17gm1010004h0102, 18gm1010004h0103, and 19gm1010004s0104 to KH), the Japan Society for the Promotion of Science (JP17KT0055, JP16H01369, and JP18H04680 to KH; JP17K15734 to DT), Keio University Specia …
FUNDING: This work was supported by AMED-Crest (16gm1010004h0101, 17gm1010004h0102, 18gm1010004h0103, and 19gm1010004s0104 to KH), th …
Structure and function of KH domains.
Valverde R, Edwards L, Regan L. Valverde R, et al. FEBS J. 2008 Jun;275(11):2712-26. doi: 10.1111/j.1742-4658.2008.06411.x. Epub 2008 Apr 15. FEBS J. 2008. PMID: 18422648 Free article. Review.
The hnRNP K homology (KH) domain was first identified in the protein human heterogeneous nuclear ribonucleoprotein K (hnRNP K) 14 years ago. ...Isolated KH domains have been seen to crystallize as monomers, dimers and tetramers, but no published data support the for …
The hnRNP K homology (KH) domain was first identified in the protein human heterogeneous nuclear ribonucleoprotein K (hnRNP K) 14 yea …
Pressure Induced Clathrate Hydrogen-Rich Superconductors KH(20) and KH(30).
Zhao W, Song H, Liu Z, Du M, Zhang Z, Liu Z, Jiang Q, Chen L, Duan D, Cui T. Zhao W, et al. Inorg Chem. 2022 Nov 14;61(45):18112-18118. doi: 10.1021/acs.inorgchem.2c02686. Epub 2022 Oct 31. Inorg Chem. 2022. PMID: 36315842
We systematically investigate the high-pressure phase diagram of the K-H system and identified two unreported clathrate extreme superhydrides KH(20) and KH(30), hosting high superconducting transition temperatures (T(c)) of 283 and 243 K at 500 GPa, respectively. .. …
We systematically investigate the high-pressure phase diagram of the K-H system and identified two unreported clathrate extreme superhydride …
Cancer Vaccines Based on Fluorine-Modified KH-1 Elicit Robust Immune Response.
Liu Y, Li B, Zheng X, Xiong D, Ye X. Liu Y, et al. Molecules. 2023 Feb 17;28(4):1934. doi: 10.3390/molecules28041934. Molecules. 2023. PMID: 36838925 Free PMC article.
The results showed that fluorine-modified N-acyl KH-1 conjugates can induce higher titers of antibodies, especially IgG, which can recognize KH-1-positive cancer cells and can eliminate cancer cells through complement-dependent cytotoxicity (CDC). The trifluoro-modi …
The results showed that fluorine-modified N-acyl KH-1 conjugates can induce higher titers of antibodies, especially IgG, which can re …
Idiopathic Pathological Ketotic Hypoglycemia: Finding the Needle in a Haystack.
Wolfsdorf JI, Derks TGJ, Drachmann D, Shah P, Thornton PS, Weinstein DA. Wolfsdorf JI, et al. Horm Res Paediatr. 2025;98(3):246-257. doi: 10.1159/000538483. Epub 2024 Mar 21. Horm Res Paediatr. 2025. PMID: 38513624 Free PMC article. Review.
Recent advances in molecular genetic testing have led to the discovery of these rare disorders. Idiopathic pathological KH is a diagnosis of exclusion that describes rare children who have abnormally limited fasting tolerance, experience recurrent episodes of KH, or …
Recent advances in molecular genetic testing have led to the discovery of these rare disorders. Idiopathic pathological KH is a diagn …
Nucleic acid-binding KH domain proteins influence a spectrum of biological pathways including as part of membrane-localized complexes.
Hasan MK, Jeannine Brady L. Hasan MK, et al. J Struct Biol X. 2024 Jun 27;10:100106. doi: 10.1016/j.yjsbx.2024.100106. eCollection 2024 Dec. J Struct Biol X. 2024. PMID: 39040530 Free PMC article.
Prokaryotic KH domain proteins are involved in integral cellular activities including cell division and protein translocation. Eukaryotic and prokaryotic KH domains share structural features, but are differentiated based on their structural organizations. ...
Prokaryotic KH domain proteins are involved in integral cellular activities including cell division and protein translocation. Eukary …
Identification of a Host-Targeted Compound to Control Typhoid Fever.
Hoang KV, Woolard K, Yang C, Melander C, Gunn JS. Hoang KV, et al. Microbiol Spectr. 2022 Jun 29;10(3):e0061922. doi: 10.1128/spectrum.00619-22. Epub 2022 May 17. Microbiol Spectr. 2022. PMID: 35579463 Free PMC article.
Subsequent screening of KH-1 commercial analogs identified 2-(4-fluorobenzyl)-1-(3-phenoxyphenyl)-1,2-dihydrochromeno[2,3-c] pyrrole-3,9-dione (KH-1-2), which is more effective in controlling Salmonella growth inside macrophages. ...In combination with suboptimal ci …
Subsequent screening of KH-1 commercial analogs identified 2-(4-fluorobenzyl)-1-(3-phenoxyphenyl)-1,2-dihydrochromeno[2,3-c] pyrrole- …
18,266 results
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