Multiomics analysis of IgM monoclonal gammopathies reveals epigenetic influence on oncogenesis via DNA methylation.
Chohan K, Paludo J, Dasari S, Mondello P, Novak JP, Abeykoon JP, Wenzl K, Yang ZZ, Jalali S, Bhardwaj V, Krull JE, Braggio E, Manske MK, Paulus A, Reeder CB, Ailawadhi S, Chanan-Khan A, Kapoor P, Kyle RA, Gertz MA, Novak AJ, Ansell SM.
Chohan K, et al.
Blood. 2024 Sep 19;144(12):1284-1289. doi: 10.1182/blood.2023023639.
Blood. 2024.
PMID: 38968152
Free article.
Currently, the role of DNA methylation in the immunoglobulin M (IgM) monoclonal gammopathy disease spectrum remains poorly understood. In the present study, a multiomics prospective analysis was conducted integrating DNA methylation, RNA sequencing (RNA-seq), and whole-exo …
Currently, the role of DNA methylation in the immunoglobulin M (IgM) monoclonal gammopathy disease spectrum remains poorly understood …