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2013 3
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Page 1
Evaluation of cytotoxic and chemotherapeutic properties of boldine in breast cancer using in vitro and in vivo models.
Paydar M, Kamalidehghan B, Wong YL, Wong WF, Looi CY, Mustafa MR. Paydar M, et al. Drug Des Devel Ther. 2014 Jun 6;8:719-33. doi: 10.2147/DDDT.S58178. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 24944509 Free PMC article.
In addition, we demonstrated that boldine induced cell cycle arrest at G2/M phase. The anticancer mechanism is associated with disruption of the mitochondrial membrane potential and release of cytochrome c in MDA-MB-231. ...
In addition, we demonstrated that boldine induced cell cycle arrest at G2/M phase. The anticancer mechanism is associated with disrup …
Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest.
Ng KB, Bustamam A, Sukari MA, Abdelwahab SI, Mohan S, Buckle MJ, Kamalidehghan B, Nadzri NM, Anasamy T, A Hadi AH, Rahman HS. Ng KB, et al. BMC Complement Altern Med. 2013 Feb 22;13:41. doi: 10.1186/1472-6882-13-41. BMC Complement Altern Med. 2013. PMID: 23432947 Free PMC article.
The cell cycle analysis indicated that boesenbergin A was able to induce G2/M phase arrest in CEMss cells. The activity of caspases -3/7, -8 and -9 was increased after treatment which indicates both intrinsic and extrinsic pathways are induced during apoptosis. ...CONCLUSI …
The cell cycle analysis indicated that boesenbergin A was able to induce G2/M phase arrest in CEMss cells. The activity of caspases - …
Inclusion Complex of Zerumbone with Hydroxypropyl- β -Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio.
Muhammad Nadzri N, Abdul AB, Sukari MA, Abdelwahab SI, Eid EE, Mohan S, Kamalidehghan B, Anasamy T, Ng KB, Syam S, Arbab IA, Rahman HS, Ali HM. Muhammad Nadzri N, et al. Evid Based Complement Alternat Med. 2013;2013:810632. doi: 10.1155/2013/810632. Epub 2013 May 8. Evid Based Complement Alternat Med. 2013. PMID: 23737847 Free PMC article.
Apoptosis was ascertained by morphological study, nuclear stain, and sub-G1 cell population accumulation with G2/M arrest. Further investigations showed the release of cytochrome c and loss of mitochondrial membrane potential, proving mitochondrial dysfunction upon the ZER …
Apoptosis was ascertained by morphological study, nuclear stain, and sub-G1 cell population accumulation with G2/M arrest. Further in …
Antiproliferative effects of imatinib mesylate on ZR‑75‑1 and MDA‑MB‑231 cell lines via PDGFR‑β, PDGF‑BB, c‑Kit and SCF expression.
Kadivar A, Ibrahim Noordin M, Aditya A, Kamalidehghan B, Davoudi ET, Sedghi R, Akbari Javar H. Kadivar A, et al. Int J Mol Med. 2018 Jul;42(1):414-424. doi: 10.3892/ijmm.2018.3590. Epub 2018 Mar 27. Int J Mol Med. 2018. PMID: 29620139
To assess the antiproliferative effects of imatinib mesylate, an MTS assay was conducted following treatment of cells with 2-10 M imatinib mesylate for 96, 120 and 144 h; accordingly the half maximal inhibitory concentration of imatinib mesylate was calculated for each ce …
To assess the antiproliferative effects of imatinib mesylate, an MTS assay was conducted following treatment of cells with 2-10 M im …
RETRACTED: Gastroprotection studies of Schiff base zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats.
Golbabapour S, Gwaram NS, Hassandarvish P, Hajrezaie M, Kamalidehghan B, Abdulla MA, Ali HM, Hadi AH, Majid NA. Golbabapour S, et al. PLoS One. 2013 Sep 13;8(9):e75036. doi: 10.1371/journal.pone.0075036. eCollection 2013. PLoS One. 2013. Retraction in: PLoS One. 2026 Jan 28;21(1):e0341791. doi: 10.1371/journal.pone.0341791. PMID: 24058648 Free PMC article. Retracted.
Ethanol (95% v/v) was orally administrated to induce superficial hemorrhagic mucosal lesions. Omeprazole (5.790 10(-5) M/kg) was used as a reference medicine. The pre-treatment with the zinc (II) complex (2.181 10(-5) and 4.362 10(-5) M/kg) protected the gastric muc …
Ethanol (95% v/v) was orally administrated to induce superficial hemorrhagic mucosal lesions. Omeprazole (5.790 10(-5) M/kg) was used …
Antiproliferation effect of imatinib mesylate on MCF7, T-47D tumorigenic and MCF 10A nontumorigenic breast cell lines via PDGFR-β, PDGF-BB, c-Kit and SCF genes.
Kadivar A, Kamalidehghan B, Akbari Javar H, Karimi B, Sedghi R, Noordin MI. Kadivar A, et al. Drug Des Devel Ther. 2017 Feb 21;11:469-481. doi: 10.2147/DDDT.S124102. eCollection 2017. Drug Des Devel Ther. 2017. PMID: 28260860 Free PMC article.
The MTS assay was conducted in therapeutic relevant concentration of 2-10 M for 96, 120 and 144 h treatment. In addition, apoptosis induction and cytostatic activity of imatinib mesylate were investigated with the terminal deoxynucleotidyl transferase dUTP nick end labeli …
The MTS assay was conducted in therapeutic relevant concentration of 2-10 M for 96, 120 and 144 h treatment. In addition, apoptosis …