Overexpression of HMGA2 in breast cancer promotes cell proliferation, migration, invasion and stemness.
Mansoori B, Duijf PHG, Mohammadi A, Najafi S, Roshani E, Shanehbandi D, Hajiasgharzadeh K, Shirjang S, Ditzel HJ, Kazemi T, Mokhtarzadeh A, Gjerstorff MF, Baradaran B.
Mansoori B, et al.
Expert Opin Ther Targets. 2020 Mar;24(3):255-265. doi: 10.1080/14728222.2020.1736559. Epub 2020 Mar 14.
Expert Opin Ther Targets. 2020.
PMID: 32172636
HMGA2 knockdown also causes cell cycle arrest in G2/M phase. In addition, we found that HMGA2 increases breast cancer cell migration and invasion (P value <0.001) and promotes the acquisition of cancer stem cell features, both in vitro, in colony formation (P value < …
HMGA2 knockdown also causes cell cycle arrest in G2/M phase. In addition, we found that HMGA2 increases breast cancer cell migration …