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Empagliflozin in Patients with Chronic Kidney Disease.
The EMPA-KIDNEY Collaborative Group; Herrington WG, Staplin N, Wanner C, Green JB, Hauske SJ, Emberson JR, Preiss D, Judge P, Mayne KJ, Ng SYA, Sammons E, Zhu D, Hill M, Stevens W, Wallendszus K, Brenner S, Cheung AK, Liu ZH, Li J, Hooi LS, Liu W, Kadowaki T, Nangaku M, Levin A, Cherney D, Maggioni AP, Pontremoli R, Deo R, Goto S, Rossello X, Tuttle KR, Steubl D, Petrini M, Massey D, Eilbracht J, Brueckmann M, Landray MJ, Baigent C, Haynes R. The EMPA-KIDNEY Collaborative Group, et al. N Engl J Med. 2023 Jan 12;388(2):117-127. doi: 10.1056/NEJMoa2204233. Epub 2022 Nov 4. N Engl J Med. 2023. PMID: 36331190 Free PMC article. Clinical Trial.
METHODS: We enrolled patients with chronic kidney disease who had an estimated glomerular filtration rate (eGFR) of at least 20 but less than 45 ml per minute per 1.73 m(2) of body-surface area, or who had an eGFR of at least 45 but less than 90 ml per minute per 1.73 m …
METHODS: We enrolled patients with chronic kidney disease who had an estimated glomerular filtration rate (eGFR) of at least 20 but less tha …
Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors.
Patel A, Göbel K, Ille S, Hinz F, Schoebe N, Bogumil H, Meyer J, Brehm M, Kardo H, Schrimpf D, Lomakin A, Ritter M, Göller P, Kerbs P, Pfeifer L, Hamelmann S, Blume C, Ippen FM, Berghaus N, Euskirchen P, Schweizer L, Hultschig C, Van Roy N, Van Dorpe J, Van der Meulen J, Loontiens S, Dedeurwaerdere F, Leske H, Halldórsson S, Fox G, Deacon S, Cahyani I, Holmes N, Wibowo S, Munro R, Martin D, Sharif A, Housley M, Goldspring R, Brandner S, Roy S, Hench J, Frank S, Unterberg A, Goidts V, Jäger N, Paine S, Smith S, Herold-Mende C, Wick W, Pfister SM, Vik-Mo EO, von Deimling A, Krieg S, Jones DT, Loose M, Schlesner M, Sill M, Sahm F. Patel A, et al. Nat Med. 2025 May;31(5):1567-1577. doi: 10.1038/s41591-025-03562-5. Epub 2025 Mar 25. Nat Med. 2025. PMID: 40133526 Free PMC article.
Sulfhydryl groups in receptor binding of thyrotropin-releasing hormone to rat amygdala.
Sharif NA, Burt DR. Sharif NA, et al. J Neurochem. 1984 Jan;42(1):209-14. doi: 10.1111/j.1471-4159.1984.tb09719.x. J Neurochem. 1984. PMID: 6315888
Heavy metals (Cd2+, Hg2+), which complex with reactive -SH residues, also potently inhibited binding. The pharmacological specificity of residual [3H]MeTRH binding in chemically modified amygdala membranes was the same as that in control preparations. ...Pretreatment of me …
Heavy metals (Cd2+, Hg2+), which complex with reactive -SH residues, also potently inhibited binding. The pharmacological specificity …