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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.
Shay JW, Homma N, Zhou R, Naseer MI, Chaudhary AG, Al-Qahtani M, Hirokawa N, Goudarzi M, Fornace AJ Jr, Baeesa S, Hussain D, Bangash M, Alghamdi F, Schulten HJ, Carracedo A, Khan I, Qashqari H, Madkhali N, Saka M, Saini KS, Jamal A, Al-Maghrabi J, Abuzenadah A, Chaudhary A, Al Qahtani M, Damanhouri G, Alkhatabi H, Goodeve A, Crookes L, Niksic N, Beauchamp N, Abuzenadah AM, Vaught J, Budowle B, Assidi M, Buhmeida A, Al-Maghrabi J, Buhmeida A, Assidi M, Merdad L, Kumar S, Miura S, Gomez K, Carracedo A, Rasool M, Rebai A, Karim S, Eldin HFN, Abusamra H, Alhathli EM, Salem N, Al-Qahtani MH, Kumar S, Faheem H, Agarwa A, Nieschlag E, Wistuba J, Damm OS, Beg MA, Abdel-Meguid TA, Mosli HA, Bajouh OS, Abuzenadah AM, Al-Qahtani MH, Coskun S, Abu-Elmagd M, Buhmeida A, Dallol A, Al-Maghrabi J, Hakamy S, Al-Qahtani W, Al-Harbi A, Hussain S, Assidi M, Al-Qahtani M, Abuzenadah A, Ozkosem B, DuBois R, Messaoudi SS, Dandana MT, Mahjoub T, Almawi WY, Abdalla S, Al-Aama MN, Elzawahry A, Takahashi T, Mimaki S, Furukawa E, Nakatsuka R, Kurosaka I, Nishigaki T, Nakamura H, Serada S, Naka T, Hirota S, Shibata T, Tsuchihara K, Nishida T, Kato M, Mehmood S, Ashraf NM, Asif A, Bilal M, Mehmood MS, Hussain … See abstract for full author list ➔ Shay JW, et al. BMC Genomics. 2016 Jul 20;17 Suppl 6(Suppl 6):487. doi: 10.1186/s12864-016-2858-0. BMC Genomics. 2016. PMID: 27454254 Free PMC article.
Abutalib, Daniele Merico, Susan Walker, Christian R. Marshall, Mehdi Zarrei, Stephen W. Scherer, Mohammad H. Al-Qahtani P78 Copy number variations in Saudi patients with intellectual disability and epilepsy Muhammad I. ...Al-Qahtani P95 Breast cancer knowledge, awar …
Abutalib, Daniele Merico, Susan Walker, Christian R. Marshall, Mehdi Zarrei, Stephen W. Scherer, Mohammad H. Al-Qahtani P78 Co …
Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.
Coy S, Wang S, Stopka SA, Lin JR, Yapp C, Ritch CC, Salhi L, Baker GJ, Rashid R, Baquer G, Regan M, Khadka P, Cole KA, Hwang J, Wen PY, Bandopadhayay P, Santi M, De Raedt T, Ligon KL, Agar NYR, Sorger PK, Touat M, Santagata S. Coy S, et al. Nat Commun. 2022 Aug 16;13(1):4814. doi: 10.1038/s41467-022-32430-w. Nat Commun. 2022. PMID: 35973991 Free PMC article.
Spatially-resolved single-cell analyses demonstrate a strong spatial correlation between tumor-CD73 and microglial-CD39, with proximity associated with poor outcomes. Similar spatial organization is present in pediatric high-grade gliomas including H3K27M-mutant diffuse mi …
Spatially-resolved single-cell analyses demonstrate a strong spatial correlation between tumor-CD73 and microglial-CD39, with proximity asso …
Resveratrol: A Double-Edged Sword in Health Benefits.
Salehi B, Mishra AP, Nigam M, Sener B, Kilic M, Sharifi-Rad M, Fokou PVT, Martins N, Sharifi-Rad J. Salehi B, et al. Biomedicines. 2018 Sep 9;6(3):91. doi: 10.3390/biomedicines6030091. Biomedicines. 2018. PMID: 30205595 Free PMC article. Review.
Nonetheless, resveratrol application is still being a major challenge for pharmaceutical industry, due to its poor solubility and bioavailability, as well as adverse effects. In this sense, this review summarized current data on resveratrol pharmacological effects....
Nonetheless, resveratrol application is still being a major challenge for pharmaceutical industry, due to its poor solubility and bio …
Management of relapses after hematopoietic cell transplantation in T-cell non-Hodgkin lymphomas.
Hamadani M, Abu Kar SM, Usmani SZ, Savani BN, Ayala E, Kharfan-Dabaja MA. Hamadani M, et al. Semin Hematol. 2014 Jan;51(1):73-86. doi: 10.1053/j.seminhematol.2013.11.005. Epub 2013 Nov 15. Semin Hematol. 2014. PMID: 24468319 Review.
The prognosis of relapsed T-cell NHL is poor, especially for those relapsing after an autologous (auto-) or allogeneic (allo-) hematopoietic cell transplantation (HCT). ...
The prognosis of relapsed T-cell NHL is poor, especially for those relapsing after an autologous (auto-) or allogeneic (allo-) hemato …
ExoU Induces Lung Endothelial Cell Damage and Activates Pro-Inflammatory Caspase-1 during Pseudomonas aeruginosa Infection.
Hardy KS, Tuckey AN, Renema P, Patel M, Al-Mehdi AB, Spadafora D, Schlumpf CA, Barrington RA, Alexeyev MF, Stevens T, Pittet JF, Wagener BM, Simmons JD, Alvarez DF, Audia JP. Hardy KS, et al. Toxins (Basel). 2022 Feb 18;14(2):152. doi: 10.3390/toxins14020152. Toxins (Basel). 2022. PMID: 35202178 Free PMC article.
ExoU is a phospholipase A(2) (PLA(2)) that hydrolyses host cell membranes, and P. aeruginosa strains expressing ExoU are associated with poor outcomes in critically ill patients with pneumonia. While the effects of ExoU on lung epithelial and immune cells are well studied, …
ExoU is a phospholipase A(2) (PLA(2)) that hydrolyses host cell membranes, and P. aeruginosa strains expressing ExoU are associated with …
Enhancing islet transplantation using a biocompatible collagen-PDMS bioscaffold enriched with dexamethasone-microplates.
Primavera R, Razavi M, Kevadiya BD, Wang J, Vykunta A, Di Mascolo D, Decuzzi P, Thakor AS. Primavera R, et al. Biofabrication. 2021 Apr 7;13(3):10.1088/1758-5090/abdcac. doi: 10.1088/1758-5090/abdcac. Biofabrication. 2021. PMID: 33455953 Free PMC article.
In contrast, diabetic animals transplanted with either islets alone or islets in bioscaffolds without DEX microplates were not able to regain glycemic control during basal conditions with overall poor islet function. Taken together, our data show that coating PDMS bioscaff …
In contrast, diabetic animals transplanted with either islets alone or islets in bioscaffolds without DEX microplates were not able to regai …
A method for isolation and identification of urinary biomarkers in patients with diabetic nephropathy.
Fisher WG, Lucas JE, Mehdi UF, Qunibi DW, Garner HR, Rosenblatt KP, Toto RD. Fisher WG, et al. Proteomics Clin Appl. 2011 Dec;5(11-12):603-12. doi: 10.1002/prca.201000156. Proteomics Clin Appl. 2011. PMID: 21956890 Free PMC article.
PURPOSE: The poor performance of current tests for predicting the onset, progression and treatment response of diabetic nephropathy has engendered a search for more sensitive and specific urinary biomarkers. ...
PURPOSE: The poor performance of current tests for predicting the onset, progression and treatment response of diabetic nephropathy h …
Enhancing physio-biochemical characteristics in okra genotypes through seed priming with biogenic zinc oxide nanoparticles synthesized from halophytic plant extracts.
Ramzan M, Parveen M, Naz G, Sharif HMA, Nazim M, Aslam S, Hussain A, Rahimi M, Alamer KH. Ramzan M, et al. Sci Rep. 2024 Oct 10;14(1):23753. doi: 10.1038/s41598-024-74129-6. Sci Rep. 2024. PMID: 39390085 Free PMC article.
Hydrogen per oxide decreased up to 87.8% with 40 ppm at 24 h in hybrid variety, while, in desi variety H(2)O(2) was reduced 88.3% with 20 ppm at 24 h. Non enzymatic antioxidant activities such as ascorbic acid, was highly increased 130.6% in hybrid at 24 h …
Hydrogen per oxide decreased up to 87.8% with 40 ppm at 24 h in hybrid variety, while, in desi variety H(2)O(2) was reduced 88 …