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Page 1
Repurposing of MitoTam: Novel Anti-Cancer Drug Candidate Exhibits Potent Activity against Major Protozoan and Fungal Pathogens.
Arbon D, Ženíšková K, Šubrtová K, Mach J, Štursa J, Machado M, Zahedifard F, Leštinová T, Hierro-Yap C, Neuzil J, Volf P, Ganter M, Zoltner M, Zíková A, Werner L, Sutak R. Arbon D, et al. Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0072722. doi: 10.1128/aac.00727-22. Epub 2022 Jul 20. Antimicrob Agents Chemother. 2022. PMID: 35856666 Free PMC article.
Antibody detection against HPV16 E7 & GP96 fragments as biomarkers in cervical cancer patients.
Bolhassani A, Zahedifard F, Taslimi Y, Taghikhani M, Nahavandian B, Rafati S. Bolhassani A, et al. Indian J Med Res. 2009 Nov;130(5):533-41. Indian J Med Res. 2009. PMID: 20090101 Free article.
Serum antibody response to HPV infections in patients was detected by Western blot and ELISA techniques based on recombinant HPV16E7 and the N-terminal and C-terminal fragments of gp96 (NT-gp96 and CT-gp96) proteins. These recombinant proteins were expressed in Escherichia …
Serum antibody response to HPV infections in patients was detected by Western blot and ELISA techniques based on recombinant HPV16E7 and the …
Enhanced protective efficacy of nonpathogenic recombinant leishmania tarentolae expressing cysteine proteinases combined with a sand fly salivary antigen.
Zahedifard F, Gholami E, Taheri T, Taslimi Y, Doustdari F, Seyed N, Torkashvand F, Meneses C, Papadopoulou B, Kamhawi S, Valenzuela JG, Rafati S. Zahedifard F, et al. PLoS Negl Trop Dis. 2014 Mar 27;8(3):e2751. doi: 10.1371/journal.pntd.0002751. eCollection 2014 Mar. PLoS Negl Trop Dis. 2014. PMID: 24675711 Free PMC article.
The contribution of NT-gp96 as an adjuvant for increasing HPV16 E7-specific immunity in C57BL /6 mouse model.
Mohit E, Bolhassani A, Zahedifard F, Taslimi Y, Rafati S. Mohit E, et al. Scand J Immunol. 2012 Jan;75(1):27-37. doi: 10.1111/j.1365-3083.2011.02620.x. Scand J Immunol. 2012. PMID: 21916914 Free article.
Regarding to previous studies, vaccination with purified HSP/antigen complexes efficiently elicit antigen-specific immune responses in mice model. The N-terminal of glycoprotein 96 (NT-gp96) has adjuvant effect and can induce effective cumulative immune response against cl …
Regarding to previous studies, vaccination with purified HSP/antigen complexes efficiently elicit antigen-specific immune responses in mice …
Comparison of Protective Potency of DNA and Live Vaccines Expressing A2-CPA-CPB-CTE Antigens against Visceral Leishmaniasis in Syrian Hamster as Preliminary Study.
Taslimi Y, Zahedifard F, Taheri T, Doroud D, Latif Dizaji S, Saljoughian N, Rafati S. Taslimi Y, et al. Iran J Parasitol. 2020 Jul-Sep;15(3):383-392. doi: 10.18502/ijpa.v15i3.4203. Iran J Parasitol. 2020. PMID: 33082803 Free PMC article.
METHODS: We evaluated the effectiveness of these DNA and live vaccination harboring A2-CPA-CPB(-CTE) in protecting hamsters against L. infantum infection using prime-boost regimens, namely DNA/DNA and Live/Live (n=9 hamsters per group). Cationic solid lipid nanoparticles ( …
METHODS: We evaluated the effectiveness of these DNA and live vaccination harboring A2-CPA-CPB(-CTE) in protecting hamsters against L. infan …
Enhanced immunogenicity of HPV16E7 accompanied by Gp96 as an adjuvant in two vaccination strategies.
Bolhassani A, Zahedifard F, Taghikhani M, Rafati S. Bolhassani A, et al. Vaccine. 2008 Jun 19;26(26):3362-70. doi: 10.1016/j.vaccine.2008.03.082. Epub 2008 Apr 18. Vaccine. 2008. PMID: 18471945
In prime-boost immunization strategies, we first immunized C57BL/6 mice with the complete open-reading frame of E7 and Gp96 (pcDNA-E7 and pcDNA-Gp96) and then boosted with rE7, rNT-gp96 (N-terminal extension of Gp96) and rCT-gp96 (C-terminal extension of Gp96) mixed with M …
In prime-boost immunization strategies, we first immunized C57BL/6 mice with the complete open-reading frame of E7 and Gp96 (pcDNA-E7 and pc …
Immunomodulatory effects of IP-10 chemokine along with PEI600-Tat delivery system in DNA vaccination against HPV infections.
Mohit E, Bolhassani A, Zahedifard F, Seyed N, Eslamifar A, Taghikhani M, Samimi-Rad K, Rafati S. Mohit E, et al. Mol Immunol. 2013 Jan;53(1-2):149-60. doi: 10.1016/j.molimm.2012.07.011. Epub 2012 Aug 25. Mol Immunol. 2013. PMID: 22926003
In the present study, three strategies including linkage to immunostimulatory molecules (N-terminal of gp96), co-administration of chemokines (IP-10 or RANTES) and PEI600-Tat as non-viral gene delivery system have been applied to enhance DNA vaccine efficacy against HPV in …
In the present study, three strategies including linkage to immunostimulatory molecules (N-terminal of gp96), co-administration of ch …
A non-pathogenic live vector as an efficient delivery system in vaccine design for the prevention of HPV16 E7-overexpressing cancers.
Hosseinzadeh S, Bolhassani A, Rafati S, Taheri T, Zahedifard F, Daemi A, Taslimi Y, Hashemi M, Memarnejadian A. Hosseinzadeh S, et al. Drug Deliv. 2013 Apr-May;20(3-4):190-8. doi: 10.3109/10717544.2013.801534. Drug Deliv. 2013. PMID: 23745741 Free article.
In current study, we used Leishmania expression system (LEXSY) for stable expression of HPV16 E7 linked to different mini-chaperones [N-/C-terminal of gp96] and compared their immunogenicity and protective effects in C57BL/6 mice against TC-1 challenge. ...
In current study, we used Leishmania expression system (LEXSY) for stable expression of HPV16 E7 linked to different mini-chaperones [N …
Different domains of glycoprotein 96 influence HPV16 E7 DNA vaccine potency via electroporation mediated delivery in tumor mice model.
Daemi A, Bolhassani A, Rafati S, Zahedifard F, Hosseinzadeh S, Doustdari F. Daemi A, et al. Immunol Lett. 2012 Dec 17;148(2):117-25. doi: 10.1016/j.imlet.2012.10.003. Epub 2012 Oct 17. Immunol Lett. 2012. PMID: 23085605
In the current study, we evaluated the effects of linkage of human papillomavirus (HPV) type 16 E7 as a model antigen to N-terminal and C-terminal of glycoprotein 96 (NT-/CT-gp96) on the potency of E7-specific immunity generated by DNA vaccines. ...Altogether, our results …
In the current study, we evaluated the effects of linkage of human papillomavirus (HPV) type 16 E7 as a model antigen to N-terminal a …