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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1954 2
1955 2
1956 1
1957 2
1959 1
1960 1
1962 1
1963 1
1965 1
1968 1
1973 1
1974 2
1975 1
1976 2
1977 1
1978 1
1979 1
1981 1
1982 1
1988 1
1989 2
1990 7
1991 6
1992 4
1993 5
1994 6
1995 12
1996 9
1997 11
1998 12
1999 14
2000 11
2001 15
2002 8
2003 20
2004 13
2005 19
2006 9
2007 23
2008 15
2009 21
2010 28
2011 31
2012 39
2013 35
2014 72
2015 103
2016 101
2017 104
2018 94
2019 93
2020 91
2021 101
2022 114
2023 113
2024 100
2025 152
2026 33

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1,504 results

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Page 1
Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies.
Bahar ME, Kim HJ, Kim DR. Bahar ME, et al. Signal Transduct Target Ther. 2023 Dec 18;8(1):455. doi: 10.1038/s41392-023-01705-z. Signal Transduct Target Ther. 2023. PMID: 38105263 Free PMC article. Review.
Autophagy, an intracellular lysosome-dependent catabolic recycling process, plays a critical role in the development of RAFi resistance in cancer. Thus, targeting RAF and autophagy could be novel treatment strategies for RAF-mutant cancers. In this review, we delve deeper …
Autophagy, an intracellular lysosome-dependent catabolic recycling process, plays a critical role in the development of RAFi resistan …
Achievements and beyond: Scientific trajectory of Professor Mohammad A. Rafi.
Omidi Y, Alavi A. Omidi Y, et al. Bioimpacts. 2021;11(1):1-4. doi: 10.34172/bi.2021.01. Epub 2020 Dec 7. Bioimpacts. 2021. PMID: 33469502 Free PMC article.
This biography highlights the scientific trajectory of Professor Mohammad A. Rafi, Ph.D., who, in particular, has greatly advanced the field of neurodegenerative disorders during his long and successful tenure at Jefferson Medical College, Thomas Jefferson University. This …
This biography highlights the scientific trajectory of Professor Mohammad A. Rafi, Ph.D., who, in particular, has greatly advanced th …
RAF inhibitors activate the integrated stress response by direct activation of GCN2.
Gilley R, Kidger AM, Neill G, Morrison E, Severson P, Byrne DP, Kenneth NS, Bollag G, Zhang C, Maia de Oliveira T, Eyers PA, Bayliss R, Masson GR, Cook SJ. Gilley R, et al. Nat Commun. 2025 Nov 17;16(1):10033. doi: 10.1038/s41467-025-65376-w. Nat Commun. 2025. PMID: 41249187 Free PMC article.
The GCN2 kinase inhibitor A-92, GCN2 RNAi, GCN2 knock-out or ISRIB (an eIF2alpha antagonist) all reversed RAFi-induced expression of ATF4 and CHOP indicating that RAFi require GCN2 to activate the ISR. ...Activation of the ISR by RAFi was abolished by a GCN2 …
The GCN2 kinase inhibitor A-92, GCN2 RNAi, GCN2 knock-out or ISRIB (an eIF2alpha antagonist) all reversed RAFi-induced expression of …
Progress in primary and integrated care.
Hawthorne K, Rafi I. Hawthorne K, et al. Future Healthc J. 2023 Nov;10(3):177. doi: 10.7861/fhj.ed.10.3.2. Future Healthc J. 2023. PMID: 38162218 Free PMC article. No abstract available.
Reply to Crawford and Biere-Rafi et al.
Kuut TA, Müller F, Nieuwkerk P, Rovers CP, Knoop H. Kuut TA, et al. Clin Infect Dis. 2023 Oct 5;77(7):1075-1077. doi: 10.1093/cid/ciad398. Clin Infect Dis. 2023. PMID: 37387679 No abstract available.
BioImpacts: An emerging global journal.
Ilghami R, Mohammadhasanzadeh H, Barar J, Rafi MA. Ilghami R, et al. Bioimpacts. 2020;10(4):207-208. doi: 10.34172/bi.2020.26. Epub 2020 Aug 24. Bioimpacts. 2020. PMID: 32983935 Free PMC article.
Sustained Tumor Control With MAPK Inhibition in BRAF V600-Mutant Adult Glial and Glioneuronal Tumors.
Berzero G, Bellu L, Baldini C, Ducray F, Guyon D, Eoli M, Silvani A, Dehais C, Idbaih A, Younan N, Nguyen-Them L, Gaillard S, Pasqualetti F, Lepage-Seydoux C, Sekkate S, Tresca P, Kas A, Gratieux J, Ammari S, Saragoussi E, Savatovsky J, Delattre JY, Hoang-Xuan K, Meyronet D, Villa C, Bielle F, Sanson M, Touat M, Di Stefano AL. Berzero G, et al. Neurology. 2021 Aug 17;97(7):e673-e683. doi: 10.1212/WNL.0000000000012330. Epub 2021 Jun 4. Neurology. 2021. PMID: 34088874
At the time that treatment with RAFi/MEKi was started, all tumors displayed radiologic features of high-grade neoplasms. Thirteen patients received RAFi as single agents (vemurafenib [n = 11], dabrafenib [n = 2]), and 15 received combinations of RAFi/MEKi (ve …
At the time that treatment with RAFi/MEKi was started, all tumors displayed radiologic features of high-grade neoplasms. Thirteen pat …
'Coinfection-helminthes and tuberculosis'.
Rafi W, Ribeiro-Rodrigues R, Ellner JJ, Salgame P. Rafi W, et al. Curr Opin HIV AIDS. 2012 May;7(3):239-44. doi: 10.1097/COH.0b013e3283524dc5. Curr Opin HIV AIDS. 2012. PMID: 22411453 Review.
Forearm Fractures.
Rafi BM, Tiwari V. Rafi BM, et al. 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 34662094 Free Books & Documents.
1,504 results