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(1)H detection and dynamic nuclear polarization-enhanced NMR of Abeta(1-42) fibrils.
Bahri S, Silvers R, Michael B, Jaudzems K, Lalli D, Casano G, Ouari O, Lesage A, Pintacuda G, Linse S, Griffin RG. Bahri S, et al. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2114413119. doi: 10.1073/pnas.2114413119. Proc Natl Acad Sci U S A. 2022. PMID: 34969859 Free PMC article.
Here, we show that these drawbacks are removed by utilizing two relatively recent additions to the repertoire of MAS NMR experiments-namely, (1)H detection and dynamic nuclear polarization (DNP). We show resolved and sensitive two-dimensional (2D) and three-dimensional (3D …
Here, we show that these drawbacks are removed by utilizing two relatively recent additions to the repertoire of MAS NMR experiments-namely, …
High-resolution structure of monomorphic Aβ1-40 fibrils.
Bahri S, Palani RS, Silvers R, Michael B, Lattanzi V, André I, Linse S, Griffin RG. Bahri S, et al. Proc Natl Acad Sci U S A. 2026 Jul 14;123(28):e2603575123. doi: 10.1073/pnas.2603575123. Epub 2026 Jul 8. Proc Natl Acad Sci U S A. 2026. PMID: 42418485
The resolved structure, with a backbone RMSD of 0.63 0.06 A, shows two monomers per filament plane, with two distinct beta-sheets (residues E11-E22 and K28-V39, respectively) running along the fibril axis with H-bonding between each plane, and the two strands linked by a …
The resolved structure, with a backbone RMSD of 0.63 0.06 A, shows two monomers per filament plane, with two distinct beta-sheets (residue …
Study of the T16189C variant and mitochondrial lineages in Tunisian and overall Mediterranean region.
Hsouna S, Ben Halim N, Lasram K, Meiloud G, Arfa I, Kerkeni E, Romdhane L, Jamoussi H, Bahri S, Ben Ammar S, Abid A, Barakat A, Houmeida A, Abdelhak S, Kefi R. Hsouna S, et al. Mitochondrial DNA A DNA Mapp Seq Anal. 2016;27(2):1558-63. doi: 10.3109/19401736.2014.953136. Epub 2015 Sep 4. Mitochondrial DNA A DNA Mapp Seq Anal. 2016. PMID: 25208176
Our findings showed positive correlation of the T16189C variant with Sub-Saharan and North African lineages, while a negative correlation was found with the Eurasian haplogroups, reaching its maximum with the Eurasian haplogroup H. The principal component analyses showed a …
Our findings showed positive correlation of the T16189C variant with Sub-Saharan and North African lineages, while a negative correlation wa …