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Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid diseases and molecular outcomes.
Sakamoto T, Leca J, Zhang X, Meydan C, Foox J, Ramachandran P, Hendrikse LD, Zhou W, Berger T, Fortin J, Chan SM, Chiang MF, Inoue S, Li WY, Chu MF, Duncan GS, Wakeham A, Lemonnier F, Tobin C, Mcwilliam R, Colonna I, Bontoux C, Jafari SM, Bowman RL, Nicolay B, Ronseaux S, Narayanaswamy R, Levine RL, Melnick AM, Mason CE, Minden MD, Mak TW. Sakamoto T, et al. Proc Natl Acad Sci U S A. 2025 May 20;122(20):e2415779122. doi: 10.1073/pnas.2415779122. Epub 2025 May 16. Proc Natl Acad Sci U S A. 2025. PMID: 40377995 Free PMC article.
The effect of voglibose on metabolic profiles in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of clinical trials.
Nowrouzi-Sohrabi P, Tabrizi R, Rezaei S, Jafari F, Hessami K, Abedi M, Jalali M, Keshavarzi P, Shahabi S, Kolahi AA, Carson-Chahhoud K, Sahebkar A, Safiri S. Nowrouzi-Sohrabi P, et al. Pharmacol Res. 2020 Sep;159:104988. doi: 10.1016/j.phrs.2020.104988. Epub 2020 Jun 3. Pharmacol Res. 2020. PMID: 32504833
However, no evidence of effect for voglibose intake on T2DM patients was observed for: fasting blood sugar (FBS) (WMD -7.43 mg/dl; 95 %CI -16.56 to 1.71; P = 0.110; I(2) = 69.3 %), serum insulin (WMD= -0.15 muU/mL; 95 %CI -0.89 to 0.60; P = 0.70; I(2) = 0.0 %), total-cholesterol …
However, no evidence of effect for voglibose intake on T2DM patients was observed for: fasting blood sugar (FBS) (WMD -7.43 mg/dl; 95 %CI -1 …
High-performance Countercurrent Chromatography to Access Rhodiola rosea Influenza Virus Inhibiting Constituents.
Langeder J, Grienke U, Döring K, Jafari M, Ehrhardt C, Schmidtke M, Rollinger JM. Langeder J, et al. Planta Med. 2021 Aug;87(10-11):818-826. doi: 10.1055/a-1228-8473. Epub 2020 Aug 11. Planta Med. 2021. PMID: 32781473 Free article.
The most promising anti-influenza activities were determined for rhodiosin, tricin, and tricin-5-O-beta-D-glucopyranoside with IC(50) values of 7.9, 13, and 15 M, respectively. The herein established high-performance countercurrent chromatographic protocol enables fast and …
The most promising anti-influenza activities were determined for rhodiosin, tricin, and tricin-5-O-beta-D-glucopyranoside with IC(50) values …
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