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Page 1
Sleep pressure accumulates in a voltage-gated lipid peroxidation memory.
Rorsman HO, Müller MA, Liu PZ, Sanchez LG, Kempf A, Gerbig S, Spengler B, Miesenböck G. Rorsman HO, et al. Nature. 2025 May;641(8061):232-239. doi: 10.1038/s41586-025-08734-4. Epub 2025 Mar 19. Nature. 2025. PMID: 40108451 Free PMC article.
Here we show that Hyperkinetic, the beta-subunit of the K(V)1 channel Shaker in Drosophila(7), forms a dynamic lipid peroxidation memory. Information is stored in the oxidation state of Hyperkinetic's nicotinamide adenine dinucleotide phosphate (NADPH) cofactor, which chan …
Here we show that Hyperkinetic, the beta-subunit of the K(V)1 channel Shaker in Drosophila(7), forms a dynamic lipid peroxidation mem …
Protease-stable DARPins as promising oral therapeutics.
Simeon RA, Zeng Y, Chonira V, Aguirre AM, Lasagna M, Baloh M, Sorg JA, Tommos C, Chen Z. Simeon RA, et al. Protein Eng Des Sel. 2021 Feb 15;34:gzab028. doi: 10.1093/protein/gzab028. Protein Eng Des Sel. 2021. PMID: 34882774 Free PMC article.
Both T10-2 and T10b enjoy a high thermo- and chemo-stability and can be expressed very efficiently in Escherichia coli (>100 mg/l in shaker flasks). We believe that, in additional to their potential as oral therapeutics against C. difficile infection, T10-2 and T10b can …
Both T10-2 and T10b enjoy a high thermo- and chemo-stability and can be expressed very efficiently in Escherichia coli (>100 mg/l in s …
Contributions of Thyroid Hormone to Cancer Metastasis.
Mousa SA, Glinsky GV, Lin HY, Ashur-Fabian O, Hercbergs A, Keating KA, Davis PJ. Mousa SA, et al. Biomedicines. 2018 Aug 22;6(3):89. doi: 10.3390/biomedicines6030089. Biomedicines. 2018. PMID: 30135398 Free PMC article. Review.
Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC.
Abud AA, Abi B, Acciarri R, Acero MA, Adames MR, Adamov G, Adamowski M, Adams D, Adinolfi M, Aduszkiewicz A, Aguilar J, Ahmad Z, Ahmed J, Aimard B, Ali-Mohammadzadeh B, Alion T, Allison K, Monsalve SA, AlRashed M, Alt C, Alton A, Alvarez R, Amedo P, Anderson J, Andreopoulos C, Andreotti M, Andrews M, Andrianala F, Andringa S, Anfimov N, Ankowski A, Antoniassi M, Antonova M, Antoshkin A, Antusch S, Aranda-Fernandez A, Arellano L, Arnold LO, Arroyave MA, Asaadi J, Asquith L, Aurisano A, Aushev V, Autiero D, Lara VA, Ayala-Torres M, Azfar F, Back A, Back H, Back JJ, Backhouse C, Bagaturia I, Bagby L, Balashov N, Balasubramanian S, Baldi P, Baller B, Bambah B, Barao F, Barenboim G, Alzas PB, Barker G, Barkhouse W, Barnes C, Barr G, Monarca JB, Barros A, Barros N, Barrow JL, Basharina-Freshville A, Bashyal A, Basque V, Batchelor C, Chagas EBD, Battat JBR, Battisti F, Bay F, Bazetto MCQ, Alba JLLB, Beacom JF, Bechetoille E, Behera B, Beigbeder C, Bellantoni L, Bellettini G, Bellini V, Beltramello O, Benekos N, Montiel CB, Neves FB, Berger J, Berkman S, Bernardini P, Berner RM, Bersani A, Bertolucci S, Betancourt M, Rodríguez AB, Bevan A, Bezawada Y, Bezerra TJC, Bhardwaj A, Bhatnagar V,… See abstract for full author list ➔ Abud AA, et al. Eur Phys J C Part Fields. 2022;82(7):618. doi: 10.1140/epjc/s10052-022-10549-w. Epub 2022 Jul 16. Eur Phys J C Part Fields. 2022. PMID: 35859696 Free PMC article.
Incubator-Free Organoid Culture in a Sealed Recirculatory System.
Rosen Y, Doganyigit K, Arul S, Wachtel E, Ehrlich D, Venuturimilli V, Mouzaya M, Oriaku S, Ndiforchu B, Kaurala G, Hernandez S, Moarefian M, Schweiger H, Cisneros A, Zeraatkar M, Geng J, Mostajo-Radji MA, Winkler E, Haussler D, Teodorescu M. Rosen Y, et al. bioRxiv [Preprint]. 2025 Sep 5:2025.09.03.673593. doi: 10.1101/2025.09.03.673593. bioRxiv. 2025. PMID: 40950033 Free PMC article. Preprint.
We demonstrate compatibility with continuous multi-week live imaging of vascular organoids and show that brain organoids in this system maintain metabolic viability, structural fidelity, and electrophysiological activity comparable to traditional shaker-based cultures in a …
We demonstrate compatibility with continuous multi-week live imaging of vascular organoids and show that brain organoids in this system main …
Strong CD4+ T-Cell Responses to Ancestral and Variant Spike Proteins Are Established by NVX-CoV2373 Severe Acute Respiratory Syndrome Coronavirus 2 Primary Vaccination.
Fries L, Formica N, Mallory RM, Zhou H, Plested JS, Kalkeri R, Moldovan I, Patel N, Albert G, Robinson M, Cho I, Chau G, Dubovsky F, Glenn GM; 2019nCoV-101 Study Group. Fries L, et al. J Infect Dis. 2023 Sep 15;228(6):734-741. doi: 10.1093/infdis/jiad163. J Infect Dis. 2023. PMID: 37210741 Free PMC article. Clinical Trial.
HgeTx1, the first K+-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad.
Schwartz EF, Schwartz CA, Gómez-Lagunas F, Zamudio FZ, Possani LD. Schwartz EF, et al. Toxicon. 2006 Dec 15;48(8):1046-53. doi: 10.1016/j.toxicon.2006.08.009. Epub 2006 Sep 5. Toxicon. 2006. PMID: 17030052
It has a molecular mass of 3950 atomic mass units (a.m.u.) and contains 36 amino acids with four disulfide bridges established between Cys1-Cys5, Cys2-Cys6, Cys3-Cys7 and Cys4-Cys8. It blocks reversibly the Shaker B K(+)-channels with a Kd of 52nM. HgeTx1 sha …
It has a molecular mass of 3950 atomic mass units (a.m.u.) and contains 36 amino acids with four disulfide bridges established …
Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.
Morrison HM, Craft J, Rivera-Lugo R, Johnson JR, Golovkine GR, Bell SL, Dodd CE, Van Dis E, Beatty WL, Margolis SR, Repasy T, Shaker I, Lee AY, Vance RE, Stanley SA, Watson RO, Krogan NJ, Portnoy DA, Penn BH, Cox JS. Morrison HM, et al. PLoS Pathog. 2023 Jun 23;19(6):e1011088. doi: 10.1371/journal.ppat.1011088. eCollection 2023 Jun. PLoS Pathog. 2023. PMID: 37352334 Free PMC article.
28 results