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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
2001 1
2006 1
2007 2
2009 1
2011 1
2014 1
2015 1
2020 1
2021 2
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11 results
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Page 1
A CRISPR Screen Reveals Resistance Mechanisms to CD3-Bispecific Antibody Therapy.
Liu SQ, Grantham A, Landry C, Granda B, Chopra R, Chakravarthy S, Deutsch S, Vogel M, Russo K, Seiss K, Tschantz WR, Rejtar T, Ruddy DA, Hu T, Aardalen K, Wagner JP, Dranoff G, D'Alessio JA. Liu SQ, et al. Among authors: aardalen k. Cancer Immunol Res. 2021 Jan;9(1):34-49. doi: 10.1158/2326-6066.CIR-20-0080. Epub 2020 Nov 11. Cancer Immunol Res. 2021. PMID: 33177106 Free article.
SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.
Wang Y, Mohseni M, Grauel A, Diez JE, Guan W, Liang S, Choi JE, Pu M, Chen D, Laszewski T, Schwartz S, Gu J, Mansur L, Burks T, Brodeur L, Velazquez R, Kovats S, Pant B, Buruzula G, Deng E, Chen JT, Sari-Sarraf F, Dornelas C, Varadarajan M, Yu H, Liu C, Lim J, Hao HX, Jiang X, Malamas A, LaMarche MJ, Geyer FC, McLaughlin M, Costa C, Wagner J, Ruddy D, Jayaraman P, Kirkpatrick ND, Zhang P, Iartchouk O, Aardalen K, Cremasco V, Dranoff G, Engelman JA, Silver S, Wang H, Hastings WD, Goldoni S. Wang Y, et al. Among authors: aardalen k. Sci Rep. 2021 Jan 14;11(1):1399. doi: 10.1038/s41598-021-80999-x. Sci Rep. 2021. PMID: 33446805 Free PMC article.
Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma.
Williams TE, Subramanian S, Verhagen J, McBride CM, Costales A, Sung L, Antonios-McCrea W, McKenna M, Louie AK, Ramurthy S, Levine B, Shafer CM, Machajewski T, Renhowe PA, Appleton BA, Amiri P, Chou J, Stuart D, Aardalen K, Poon D. Williams TE, et al. Among authors: aardalen k. ACS Med Chem Lett. 2015 Aug 3;6(9):961-5. doi: 10.1021/ml500526p. eCollection 2015 Sep 10. ACS Med Chem Lett. 2015. PMID: 26396681 Free PMC article.
Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target.
Chen G, Chakravarti N, Aardalen K, Lazar AJ, Tetzlaff MT, Wubbenhorst B, Kim SB, Kopetz S, Ledoux AA, Gopal YN, Pereira CG, Deng W, Lee JS, Nathanson KL, Aldape KD, Prieto VG, Stuart D, Davies MA. Chen G, et al. Among authors: aardalen k. Clin Cancer Res. 2014 Nov 1;20(21):5537-46. doi: 10.1158/1078-0432.CCR-13-3003. Epub 2014 May 6. Clin Cancer Res. 2014. PMID: 24803579 Free PMC article.
Design, structure-activity relationships and in vivo characterization of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones: a novel class of receptor tyrosine kinase inhibitors.
Renhowe PA, Pecchi S, Shafer CM, Machajewski TD, Jazan EM, Taylor C, Antonios-McCrea W, McBride CM, Frazier K, Wiesmann M, Lapointe GR, Feucht PH, Warne RL, Heise CC, Menezes D, Aardalen K, Ye H, He M, Le V, Vora J, Jansen JM, Wernette-Hammond ME, Harris AL. Renhowe PA, et al. Among authors: aardalen k. J Med Chem. 2009 Jan 22;52(2):278-92. doi: 10.1021/jm800790t. J Med Chem. 2009. PMID: 19113866
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