Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 2
1998 3
1999 1
2000 4
2001 3
2002 5
2003 3
2004 5
2005 5
2006 9
2007 7
2008 8
2009 12
2010 3
2011 11
2012 6
2013 6
2014 5
2015 9
2016 3
2017 7
2018 8
2019 8
2020 11
2021 9
2022 10
2023 9
2024 8

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

162 results

Results by year

Filters applied: . Clear all
Page 1
ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases.
Qi B, Newcomer RG, Sang QX. Qi B, et al. Curr Pharm Des. 2009;15(20):2336-48. doi: 10.2174/138161209788682352. Curr Pharm Des. 2009. PMID: 19601835 Review.
ADAM19 plays essential roles in embryo implantation, cardiovascular morphogenesis, neurogenesis, and other developmental processes. ...It is also over-expressed by many human cancerous cell lines including cancers of the colon, ovary, lung, and brain. Abnormally high expre …
ADAM19 plays essential roles in embryo implantation, cardiovascular morphogenesis, neurogenesis, and other developmental processes. . …
Comparison of ADAM19 and CUEDC2 expression in EHCC and their clinicopathological significance.
Xu S, Huang S, Li D, Zou Q, Yuan Y, Yang Z. Xu S, et al. Biomark Med. 2020 Nov;14(16):1573-1584. doi: 10.2217/bmm-2020-0321. Epub 2020 Sep 22. Biomark Med. 2020. PMID: 32960074

Result: The expression of ADAM19 and CUEDC2 were significantly higher in EHCC (p < 0.05). ADAM19 expression was positive correlated with CUEDC2 expression in EHCC (p < 0.05). The overall survival time of those with positive expression of ADAM19 and CUED

…

Result: The expression of ADAM19 and CUEDC2 were significantly higher in EHCC (p < 0.05). ADAM19 expression was positive co

…
ADAM19 cleaves the PTH receptor and associates with brachydactyly type E.
Aydin A, Klenk C, Nemec K, Işbilir A, Martin LM, Zauber H, Rrustemi T, Toka HR, Schuster H, Gong M, Stricker S, Bock A, Bähring S, Selbach M, Lohse MJ, Luft FC. Aydin A, et al. Life Sci Alliance. 2024 Feb 8;7(4):e202302400. doi: 10.26508/lsa.202302400. Print 2024 Apr. Life Sci Alliance. 2024. PMID: 38331475 Free PMC article.
WT ADAM19 cleaved PTHR1, while mutated ADAM-19 did not. We mapped the cleavage site that we verified with mass spectrometry between amino acids 64-65. ADAM-19 cleavage increased G(q) and decreased G(s) activation. Moreover, perturbed PTHR1 cleavage by ADAM19 increas …
WT ADAM19 cleaved PTHR1, while mutated ADAM-19 did not. We mapped the cleavage site that we verified with mass spectrometry between a …
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in Mouse.
Li H, House J, Nichols C, Gruzdev A, Ward J, Li JL, Wyss A, Haque E, Edin M, Elmore S, Mahler B, Degraff L, Shi M, Zeldin D, London S. Li H, et al. Res Sq [Preprint]. 2024 Apr 8:rs.3.rs-4207678. doi: 10.21203/rs.3.rs-4207678/v1. Res Sq. 2024. Update in: Lung. 2024 Oct;202(5):659-672. doi: 10.1007/s00408-024-00738-7 PMID: 38659817 Free PMC article. Updated. Preprint.
Single nucleotide polymorphisms in a disintegrin and metalloprotease domain 19 (ADAM19) are consistently related to pulmonary function in GWAS. Thus, we used a mouse model to investigate the causal link between Adam19 and pulmonary function. METHODS: We created an …
Single nucleotide polymorphisms in a disintegrin and metalloprotease domain 19 (ADAM19) are consistently related to pulmonary functio …
ADAM19 and TUBB1 Correlate with Tumor Infiltrating Immune Cells and Predicts Prognosis in Osteosarcoma.
Wang J, Gong M, Xiong Z, Zhao Y, Xing D. Wang J, et al. Comb Chem High Throughput Screen. 2023;26(1):135-148. doi: 10.2174/1386207325666220406112305. Comb Chem High Throughput Screen. 2023. PMID: 35388751
ADAM19 expression positively correlated with naive B cells and negatively correlated with activated dendritic cells infiltrating abundance. ...A total of 56 drugs were found to target TUBB1. CONCLUSION: ADAM19 and TUBB1 could be prognostic biomarkers in osteosarcoma …
ADAM19 expression positively correlated with naive B cells and negatively correlated with activated dendritic cells infiltrating abun …
ADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice.
Weerasekera L, Rudnicka C, Sang QX, Curran JE, Johnson MP, Moses EK, Göring HH, Blangero J, Hricova J, Schlaich M, Matthews VB. Weerasekera L, et al. Mediators Inflamm. 2017;2017:7281986. doi: 10.1155/2017/7281986. Epub 2017 Feb 7. Mediators Inflamm. 2017. PMID: 28265178 Free PMC article.
Secondly, we examined the expression of ADAM19 in liver and gonadal white adipose tissue using an in vivo diet induced obesity mouse model. ...Our novel data suggest that ADAM19 is pro-obesogenic and enhances insulin resistance. Therefore, neutralisation of ADAM1 …
Secondly, we examined the expression of ADAM19 in liver and gonadal white adipose tissue using an in vivo diet induced obesity mouse …
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in a Mouse Knockout Model.
Li H, House JS, Nichols CE, Gruzdev A, Ward JM, Li JL, Wyss AB, Haque E, Edin ML, Elmore SA, Mahler BW, Degraff LM, Shi M, Zeldin DC, London SJ. Li H, et al. Lung. 2024 Oct;202(5):659-672. doi: 10.1007/s00408-024-00738-7. Epub 2024 Aug 17. Lung. 2024. PMID: 39153120 Free PMC article.
Single nucleotide polymorphisms in a disintegrin and metalloprotease domain 19 (ADAM19) are consistently related to pulmonary function in GWAS. Thus, we used a mouse model to investigate the causal link between Adam19 and pulmonary function. METHODS: We created an …
Single nucleotide polymorphisms in a disintegrin and metalloprotease domain 19 (ADAM19) are consistently related to pulmonary functio …
ADAM19 is tightly associated with constitutive Alzheimer's disease APP alpha-secretase in A172 cells.
Tanabe C, Hotoda N, Sasagawa N, Sehara-Fujisawa A, Maruyama K, Ishiura S. Tanabe C, et al. Biochem Biophys Res Commun. 2007 Jan 5;352(1):111-7. doi: 10.1016/j.bbrc.2006.10.181. Epub 2006 Nov 9. Biochem Biophys Res Commun. 2007. PMID: 17112471
To elucidate whether new proteases are involved in the processing of amyloid precursor protein (APP), we examined catalytically active ADAM12 and ADAM19 as candidates alpha-secretases. The overexpression of ADAM19 in HEK293 cells resulted in an increase in sAPPalpha …
To elucidate whether new proteases are involved in the processing of amyloid precursor protein (APP), we examined catalytically active ADAM1 …
ADAM19 autolysis is activated by LPS and promotes non-classical secretion of cysteine-rich protein 2.
Tanabe C, Hotoda N, Sasagawa N, Futai E, Komano H, Ishiura S. Tanabe C, et al. Biochem Biophys Res Commun. 2010 Jun 11;396(4):927-32. doi: 10.1016/j.bbrc.2010.05.025. Epub 2010 May 9. Biochem Biophys Res Commun. 2010. PMID: 20460109
CRIP2 secretion was increased by overexpression of ADAM19 and decreased by suppression of ADAM19 expression. Moreover, CRIP2 secretion increased in parallel with the autolytic processing of ADAM19 stimulated by lipopolysaccharide. These findings suggest that …
CRIP2 secretion was increased by overexpression of ADAM19 and decreased by suppression of ADAM19 expression. Moreover, CRIP2 s …
Catalytic properties of ADAM19.
Chesneau V, Becherer JD, Zheng Y, Erdjument-Bromage H, Tempst P, Blobel CP. Chesneau V, et al. J Biol Chem. 2003 Jun 20;278(25):22331-40. doi: 10.1074/jbc.M302781200. Epub 2003 Apr 7. J Biol Chem. 2003. PMID: 12682046 Free article.
This suggests a potential role for ADAM19 in shedding TRANCE in cells where both molecules are highly expressed, such as in osteoblasts. ...The identification of potential in vitro substrates offers the basis for further functional studies of ADAM19 in cells and in …
This suggests a potential role for ADAM19 in shedding TRANCE in cells where both molecules are highly expressed, such as in osteoblas …
162 results