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A method and server for predicting damaging missense mutations.
Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. Adzhubei IA, et al. Nat Methods. 2010 Apr;7(4):248-9. doi: 10.1038/nmeth0410-248. Nat Methods. 2010. PMID: 20354512 Free PMC article. No abstract available.
Erratum.
Schmidt S, Gerasimova A, Kondrashov FA, Adzhubei IA, Kondrashov AS, Sunyaev S. Schmidt S, et al. Among authors: adzhubei ia. PLoS Genet. 2008 Dec;4(12):10.1371/annotation/a81b1fab-890c-447b-a308-5bc8ca3eb21d. doi: 10.1371/annotation/a81b1fab-890c-447b-a308-5bc8ca3eb21d. Epub 2008 Dec 10. PLoS Genet. 2008. PMID: 19096535 Free PMC article.
Hypermutable non-synonymous sites are under stronger negative selection.
Schmidt S, Gerasimova A, Kondrashov FA, Adzhubei IA, Adzuhbei IA, Kondrashov AS, Sunyaev S. Schmidt S, et al. Among authors: adzhubei ia. PLoS Genet. 2008 Nov;4(11):e1000281. doi: 10.1371/journal.pgen.1000281. Epub 2008 Nov 28. PLoS Genet. 2008. PMID: 19043566 Free PMC article.
A universal trend of amino acid gain and loss in protein evolution.
Jordan IK, Kondrashov FA, Adzhubei IA, Wolf YI, Koonin EV, Kondrashov AS, Sunyaev S. Jordan IK, et al. Among authors: adzhubei ia. Nature. 2005 Feb 10;433(7026):633-8. doi: 10.1038/nature03306. Epub 2005 Jan 19. Nature. 2005. PMID: 15660107
19 results