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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2001 2
2002 5
2003 3
2004 3
2005 1
2006 1
2007 2
2008 2
2009 1
2010 1
2011 5
2012 3
2013 4
2014 3
2015 4
2016 12
2017 9
2018 11
2019 3
2020 9
2021 21
2022 5
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106 results
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Page 1
Serine-linked PARP1 auto-modification controls PARP inhibitor response.
Prokhorova E, Zobel F, Smith R, Zentout S, Gibbs-Seymour I, Schützenhofer K, Peters A, Groslambert J, Zorzini V, Agnew T, Brognard J, Nielsen ML, Ahel D, Huet S, Suskiewicz MJ, Ahel I. Prokhorova E, et al. Among authors: ahel i. Nat Commun. 2021 Jul 1;12(1):4055. doi: 10.1038/s41467-021-24361-9. Nat Commun. 2021. PMID: 34210965 Free PMC article.
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ. Hewitt G, et al. Among authors: ahel i. Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333017 Free PMC article.
CARM1 regulates replication fork speed and stress response by stimulating PARP1.
Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, Poirier GG, Zou L. Genois MM, et al. Among authors: ahel i. Mol Cell. 2021 Feb 18;81(4):784-800.e8. doi: 10.1016/j.molcel.2020.12.010. Epub 2021 Jan 6. Mol Cell. 2021. PMID: 33412112 Free PMC article.
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease.
Prokhorova E, Agnew T, Wondisford AR, Tellier M, Kaminski N, Beijer D, Holder J, Groslambert J, Suskiewicz MJ, Zhu K, Reber JM, Krassnig SC, Palazzo L, Murphy S, Nielsen ML, Mangerich A, Ahel D, Baets J, O'Sullivan RJ, Ahel I. Prokhorova E, et al. Among authors: ahel i. Mol Cell. 2021 Jun 17;81(12):2640-2655.e8. doi: 10.1016/j.molcel.2021.04.028. Epub 2021 May 20. Mol Cell. 2021. PMID: 34019811 Free PMC article.
ADP-ribosyltransferases, an update on function and nomenclature.
Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. Lüscher B, et al. Among authors: ahel i. FEBS J. 2021 Jul 29:10.1111/febs.16142. doi: 10.1111/febs.16142. Online ahead of print. FEBS J. 2021. PMID: 34323016 Free article.
HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.
Suskiewicz MJ, Zobel F, Ogden TEH, Fontana P, Ariza A, Yang JC, Zhu K, Bracken L, Hawthorne WJ, Ahel D, Neuhaus D, Ahel I. Suskiewicz MJ, et al. Among authors: ahel i. Nature. 2020 Mar;579(7800):598-602. doi: 10.1038/s41586-020-2013-6. Epub 2020 Feb 6. Nature. 2020. PMID: 32028527 Free PMC article.
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Carvalho Martins L, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, Peters JK, Moritz M, Herrera N, Kratochvil HT; QCRG Structural Biology Consortium, Aimon A, Bennett JM, Brandao Neto J, Cohen AE, Dias A, Douangamath A, Dunnett L, Fedorov O, Ferla MP, Fuchs MR, Gorrie-Stone TJ, Holton JM, Johnson MG, Krojer T, Meigs G, Powell AJ, Rack JGM, Rangel VL, Russi S, Skyner RE, Smith CA, Soares AS, Wierman JL, Zhu K, O'Brien P, Jura N, Ashworth A, Irwin JJ, Thompson MC, Gestwicki JE, von Delft F, Shoichet BK, Fraser JS, Ahel I. Schuller M, et al. Among authors: ahel i. Sci Adv. 2021 Apr 14;7(16):eabf8711. doi: 10.1126/sciadv.abf8711. Print 2021 Apr. Sci Adv. 2021. PMID: 33853786 Free PMC article.
ADP-ribosylation of DNA and RNA.
Groslambert J, Prokhorova E, Ahel I. Groslambert J, et al. Among authors: ahel i. DNA Repair (Amst). 2021 Sep;105:103144. doi: 10.1016/j.dnarep.2021.103144. Epub 2021 Jun 3. DNA Repair (Amst). 2021. PMID: 34116477 Free PMC article. Review.
Detecting ADP-Ribosylation in RNA.
Munnur D, Ahel I. Munnur D, et al. Among authors: ahel i. Methods Mol Biol. 2021;2298:231-243. doi: 10.1007/978-1-0716-1374-0_15. Methods Mol Biol. 2021. PMID: 34085249
106 results