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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1999 1
2001 6
2002 3
2003 6
2004 7
2005 11
2006 11
2007 17
2008 15
2009 10
2010 6
2011 11
2012 26
2013 24
2014 29
2015 32
2016 28
2017 50
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2020 45
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2022 49
2023 39
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501 results

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Page 1
Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes.
Panda SK, Peng V, Sudan R, Ulezko Antonova A, Di Luccia B, Ohara TE, Fachi JL, Grajales-Reyes GE, Jaeger N, Trsan T, Gilfillan S, Cella M, Colonna M. Panda SK, et al. Immunity. 2023 Apr 11;56(4):797-812.e4. doi: 10.1016/j.immuni.2023.01.023. Epub 2023 Feb 16. Immunity. 2023. PMID: 36801011 Free PMC article.
AHRR deficiency reduced IEL representation in a cell-intrinsic fashion. Single-cell RNA sequencing revealed an oxidative stress profile in Ahrr(-/-) IELs. AHRR deficiency unleashed AHR-induced expression of CYP1A1, a monooxygenase that generates reactive oxyg
AHRR deficiency reduced IEL representation in a cell-intrinsic fashion. Single-cell RNA sequencing revealed an oxidative stress profi
AhRR methylation contributes to disease progression in urothelial bladder cancer.
El-Haddad NW, El Kawak M, El Asmar K, Jabbour ME, Moussa MA, Habib RR, Dhaini HR. El-Haddad NW, et al. Cancer Biomark. 2022;35(2):167-177. doi: 10.3233/CBM-220002. Cancer Biomark. 2022. PMID: 36093686 Free PMC article.
Additionally, studies have shown that smoking demethylates the (AhRR) gene in blood, suggesting AhRR demethylation as a specific serum smoking biomarker. ...RESULTS: Results showed significantly higher AhRR percent methylation in muscle-invasive compared to n …
Additionally, studies have shown that smoking demethylates the (AhRR) gene in blood, suggesting AhRR demethylation as a specif …
AhR signaling pathways and regulatory functions.
Larigot L, Juricek L, Dairou J, Coumoul X. Larigot L, et al. Biochim Open. 2018 Jun 11;7:1-9. doi: 10.1016/j.biopen.2018.05.001. eCollection 2018 Dec. Biochim Open. 2018. PMID: 30003042 Free PMC article. Review.
The arylhydrocarbon receptor repressor (AhRR): structure, expression, and function.
Haarmann-Stemmann T, Abel J. Haarmann-Stemmann T, et al. Biol Chem. 2006 Sep;387(9):1195-9. doi: 10.1515/BC.2006.147. Biol Chem. 2006. PMID: 16972786 Review.
An inhibitory activity of the AhRR on AhR signaling was proposed from overexpression studies. However, there are not sufficient data showing such functional activity of the AhRR in vivo. This short overview summarizes the present knowledge about the AhRR and …
An inhibitory activity of the AhRR on AhR signaling was proposed from overexpression studies. However, there are not sufficient data …
AHRR contributes to inflammatory lymphangiogenesis by activating the EPAS1/VEGFD signaling axis in head and neck cancer.
Hu A, Zhang JW, Yang LY, Qiao PP, Lu D. Hu A, et al. Am J Cancer Res. 2022 Feb 15;12(2):537-548. eCollection 2022. Am J Cancer Res. 2022. PMID: 35261785 Free PMC article.
In this study, we explored that EPAS1 dimerizes with HIF-1beta during lymphangiogenes and tumor growth, inducing expression of many genes, including vascular endothelial growth factor-d (VEGFD). AHRR wild-type (Ahrr (+/+)) transgenic carcinoma of the mice develop tu …
In this study, we explored that EPAS1 dimerizes with HIF-1beta during lymphangiogenes and tumor growth, inducing expression of many genes, i …
AhRR and PPP1R3C: Potential Prognostic Biomarkers for Serous Ovarian Cancer.
Ardizzoia A, Jemma A, Redaelli S, Silva M, Bentivegna A, Lavitrano M, Conconi D. Ardizzoia A, et al. Int J Mol Sci. 2023 Jul 14;24(14):11455. doi: 10.3390/ijms241411455. Int J Mol Sci. 2023. PMID: 37511212 Free PMC article.
Furthermore, AhRR and PPP1R3C's increased expression was maintained in some CSC subpopulations, reinforcing their potential role in ovarian cancer. In conclusion, we reported for the first time, to the best of our knowledge, a prognostic role of AhRR and PPP1R3C exp …
Furthermore, AhRR and PPP1R3C's increased expression was maintained in some CSC subpopulations, reinforcing their potential role in o …
AHRR Hypomethylation mediates the association between maternal smoking and metabolic profiles in children.
Vidal AC, Chandramouli SA, Marchesoni J, Brown N, Liu Y, Murphy SK, Maguire R, Wang Y, Abdelmalek MF, Mavis AM, Bashir MR, Jima D, Skaar DA, Hoyo C, Moylan CA. Vidal AC, et al. Hepatol Commun. 2023 Sep 27;7(10):e0243. doi: 10.1097/HC9.0000000000000243. eCollection 2023 Oct 1. Hepatol Commun. 2023. PMID: 37755881 Free PMC article.
Hypomethylation of cg05575921 in the aryl hydrocarbon receptor repressor (AHRR) gene is associated with in utero tobacco smoke exposure. In this study, we evaluated whether AHRR hypomethylation mediates the association between maternal smoking and metabolic dysfunct …
Hypomethylation of cg05575921 in the aryl hydrocarbon receptor repressor (AHRR) gene is associated with in utero tobacco smoke exposu …
AHRR (cg05575921) methylation extent of leukocyte DNA and lung cancer survival.
Kemp Jacobsen K, Johansen JS, Mellemgaard A, Bojesen SE. Kemp Jacobsen K, et al. PLoS One. 2019 Feb 7;14(2):e0211745. doi: 10.1371/journal.pone.0211745. eCollection 2019. PLoS One. 2019. PMID: 30730943 Free PMC article.
It is unknown if AHRR (cg05575921) hypomethylation is associated with reduced survival among lung cancer patients. ...CONCLUSION: AHRR (cg05575921) methylation is linked to smoking but does not provide independent prognostic information in lung cancer patients....
It is unknown if AHRR (cg05575921) hypomethylation is associated with reduced survival among lung cancer patients. ...CONCLUSION: …
AHRR (cg05575921) Methylation Safely Improves Specificity of Lung Cancer Screening Eligibility Criteria: A Cohort Study.
Jacobsen KK, Schnohr P, Jensen GB, Bojesen SE. Jacobsen KK, et al. Cancer Epidemiol Biomarkers Prev. 2022 Apr 1;31(4):758-765. doi: 10.1158/1055-9965.EPI-21-1059. Cancer Epidemiol Biomarkers Prev. 2022. PMID: 35064064
BACKGROUND: Screening reduces lung cancer mortality, but specificities of eligibility criteria are low. We tested if leukocyte AHRR(cg05575921) methylation improves specificity of lung cancer screening eligibility criteria. ...Screening eligibility criteria (DANTE, DLCST, …
BACKGROUND: Screening reduces lung cancer mortality, but specificities of eligibility criteria are low. We tested if leukocyte AHRR(c …
Altered DNA methylation within DNMT3A, AHRR, LTA/TNF loci mediates the effect of smoking on inflammatory bowel disease.
Zhang H, Kalla R, Chen J, Zhao J, Zhou X, Adams A, Noble A, Ventham NT, Wellens J, Ho GT, Dunlop MG, Nowak JK, Ding Y, Liu Z, Satsangi J, Theodoratou E, Li X. Zhang H, et al. Nat Commun. 2024 Jan 18;15(1):595. doi: 10.1038/s41467-024-44841-y. Nat Commun. 2024. PMID: 38238335 Free PMC article.
DNA methylation alteration at cg17742416 [DNMT3A] is linked to both CD (P = 7.30 10(-8)) and UC (P = 1.04 10(-4)) risk, while cg03599224 [LTA/TNF] is associated with CD risk (P = 1.91 10(-6)), and cg14647125 [AHRR] and cg23916896 [AHRR] are linked to UC risk (P = 0. …
DNA methylation alteration at cg17742416 [DNMT3A] is linked to both CD (P = 7.30 10(-8)) and UC (P = 1.04 10(-4)) risk, while cg03599224 [LT …
501 results