Aidasani D[au] - Search Results

Year	Number of Results
2008	1
2009	1
2011	1
2012	2
2014	1
2024	0

1

Substrate redox potential controls superoxide production kinetics in the cytochrome bc complex.

Cape JL, Aidasani D, Kramer DM, Bowman MK. Cape JL, et al. Among authors: aidasani d. Biochemistry. 2009 Nov 17;48(45):10716-23. doi: 10.1021/bi901205w. Biochemistry. 2009. PMID: 19810688 Free PMC article.

2

P450-mediated O-demethylated metabolite is responsible for rat hepatobiliary toxicity of pyridyltriazine-containing PI3K inhibitors.

Subramanian R, Aidasani D, Bailey K, Branstetter D, Everds N, Jiang J, Norman MH, Primack R, Skiles GL, Soto I, Stec MM, Wagner M, Wu T, Zhu X, Lebrec H. Subramanian R, et al. Among authors: aidasani d. Toxicol Sci. 2014 Nov;142(1):298-310. doi: 10.1093/toxsci/kfu178. Epub 2014 Aug 26. Toxicol Sci. 2014. PMID: 25159132

3

Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511.

Norman MH, Andrews KL, Bo YY, Booker SK, Caenepeel S, Cee VJ, D'Angelo ND, Freeman DJ, Herberich BJ, Hong FT, Jackson CL, Jiang J, Lanman BA, Liu L, McCarter JD, Mullady EL, Nishimura N, Pettus LH, Reed AB, Miguel TS, Smith AL, Stec MM, Tadesse S, Tasker A, Aidasani D, Zhu X, Subramanian R, Tamayo NA, Wang L, Whittington DA, Wu B, Wu T, Wurz RP, Yang K, Zalameda L, Zhang N, Hughes PE. Norman MH, et al. Among authors: aidasani d. J Med Chem. 2012 Sep 13;55(17):7796-816. doi: 10.1021/jm300846z. Epub 2012 Aug 30. J Med Chem. 2012. PMID: 22897589

4

Novel cytochrome p450 bioactivation of a terminal phenyl acetylene group: formation of a one-carbon loss benzaldehyde and other oxidative products in the presence of N-acetyl cysteine or glutathione.

Subramanian R, Tam J, Aidasani D, Reid DL, Skiles GL. Subramanian R, et al. Among authors: aidasani d. Chem Res Toxicol. 2011 May 16;24(5):677-86. doi: 10.1021/tx1004375. Epub 2011 Mar 11. Chem Res Toxicol. 2011. PMID: 21395287

5

Sequential metabolism of AMG 487, a novel CXCR3 antagonist, results in formation of quinone reactive metabolites that covalently modify CYP3A4 Cys239 and cause time-dependent inhibition of the enzyme.

Henne KR, Tran TB, VandenBrink BM, Rock DA, Aidasani DK, Subramanian R, Mason AK, Stresser DM, Teffera Y, Wong SG, Johnson MG, Chen X, Tonn GR, Wong BK. Henne KR, et al. Among authors: aidasani dk. Drug Metab Dispos. 2012 Jul;40(7):1429-40. doi: 10.1124/dmd.112.045708. Epub 2012 Apr 19. Drug Metab Dispos. 2012. PMID: 22517972

6

In vitro drug-drug interaction screens for canine veterinary medicines: evaluation of cytochrome P450 reversible inhibition.

Aidasani D, Zaya MJ, Malpas PB, Locuson CW. Aidasani D, et al. Drug Metab Dispos. 2008 Aug;36(8):1512-8. doi: 10.1124/dmd.108.021196. Epub 2008 Apr 30. Drug Metab Dispos. 2008. PMID: 18448570

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